Results 131 to 140 of about 10,955 (224)
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Abstract Objective This review aimed to quantify the association between Type 2 Diabetes (T2D) and the risk of fracture at various anatomical sites by synthesising data from cohort studies. Methods A systematic search was conducted across Medline, Embase, CINAHL and Web of Science databases, from inception to 10 June 2025.
Sara Naderpour +9 more
wiley +1 more source
Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton +8 more
wiley +1 more source
Abstract Pressure ulcers can be common in the elderly, and loss of sensation can play a fundamental role in the development of these injuries. The aim of this study was to assess the effects of age and sex on non‐noxious thermal and wetness perception (via magnitude estimation), alongside pressure‐ and thermal‐pain thresholds, at the heel, sternum and ...
Miriam Martini +8 more
wiley +1 more source
Concomitant optic nerve transection and chorioretinitis sclopetaria [PDF]
Mehrdad Mohammadpour +6 more
core +1 more source
Symptoms of imbalance associated with cervical spine pathology [PDF]
The goals of the present study are: to determine the prevalence of dizziness or imbalance in a population of patients with cervical-spine pathology as compared to that in the general population; to determine correlations between cervical spinal pathology
Rieke, Catherine Clara
core +1 more source
Real-time visualization of ultrasound-guided retrobulbar blockade: an imaging study [PDF]
Background Retrobulbar anaesthesia allows eye surgery in awake patients. Severe complications of the blind techniques are reported. Ultrasound-guided needle introduction and direct visualization of the spread of local anaesthetic may improve quality and ...
Eichenberger, U. +4 more
core
Correction of retinal ischemia/reperfusion by 3-(1H-benzimidazol-2-il)-1,2,2-trimethyl cyclopentancarbonic acid in experiment [PDF]
Results of ocular fundus studies revealed the most pronounced protective effects of 3-(1Hbenzimidazol-2-il)-1,2,2-trimethyl cyclopentancarbonic acid in a dose 50 mg/kg on the model of retinal ischemiareperfusion in Wistar rats, which is reflected in the ...
Bunyatyan, N. D. +4 more
core
Photostimulation of mitochondria as a treatment for retinal neurodegeneration [PDF]
Beirne, Kathy +2 more
core +2 more sources

