Results 131 to 140 of about 10,955 (224)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos   +16 more
wiley   +1 more source

Association between type 2 diabetes and site‐specific fracture risk: A systematic review and meta‐analysis of cohort studies including over 13 million participants

open access: yesDiabetic Medicine, Volume 43, Issue 5, May 2026.
Abstract Objective This review aimed to quantify the association between Type 2 Diabetes (T2D) and the risk of fracture at various anatomical sites by synthesising data from cohort studies. Methods A systematic search was conducted across Medline, Embase, CINAHL and Web of Science databases, from inception to 10 June 2025.
Sara Naderpour   +9 more
wiley   +1 more source

Pregabalin contributes to increased recovery time from isoflurane anaesthesia for magnetic resonance imaging in horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 736-746, May 2026.
Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton   +8 more
wiley   +1 more source

Sex and age differences in mechanical, thermal and wetness perception across skin sites at risk of pressure ulcers: A quantitative sensory testing study

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2553-2563, 1 May 2026.
Abstract Pressure ulcers can be common in the elderly, and loss of sensation can play a fundamental role in the development of these injuries. The aim of this study was to assess the effects of age and sex on non‐noxious thermal and wetness perception (via magnitude estimation), alongside pressure‐ and thermal‐pain thresholds, at the heel, sternum and ...
Miriam Martini   +8 more
wiley   +1 more source

Concomitant optic nerve transection and chorioretinitis sclopetaria [PDF]

open access: yes, 2005
Mehrdad Mohammadpour   +6 more
core   +1 more source

Symptoms of imbalance associated with cervical spine pathology [PDF]

open access: yes, 2008
The goals of the present study are: to determine the prevalence of dizziness or imbalance in a population of patients with cervical-spine pathology as compared to that in the general population; to determine correlations between cervical spinal pathology
Rieke, Catherine Clara
core   +1 more source

Real-time visualization of ultrasound-guided retrobulbar blockade: an imaging study [PDF]

open access: yes, 2017
Background Retrobulbar anaesthesia allows eye surgery in awake patients. Severe complications of the blind techniques are reported. Ultrasound-guided needle introduction and direct visualization of the spread of local anaesthetic may improve quality and ...
Eichenberger, U.   +4 more
core  

Correction of retinal ischemia/reperfusion by 3-(1H-benzimidazol-2-il)-1,2,2-trimethyl cyclopentancarbonic acid in experiment [PDF]

open access: yes, 2018
Results of ocular fundus studies revealed the most pronounced protective effects of 3-(1Hbenzimidazol-2-il)-1,2,2-trimethyl cyclopentancarbonic acid in a dose 50 mg/kg on the model of retinal ischemiareperfusion in Wistar rats, which is reflected in the ...
Bunyatyan, N. D.   +4 more
core  

Pattern of eye casualty clinic cases [PDF]

open access: yes, 2008
Ehab EhabI Wasfi   +4 more
core   +1 more source

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