Results 11 to 20 of about 1,163,658 (291)

Treatment resistance in schizophrenia: a meta-analysis of prevalence and correlates [PDF]

Brazilian Journal of Psychiatry, 2023
Objectives: To determine the prevalence and correlates of treatment-resistant schizophrenia (TRS) through a systematic review and meta-analysis. Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria, an
Elton Diniz, Lais Fonseca, Deyvis Rocha, Alisson Trevizol, Raphael Cerqueira, Bruno Ortiz, André R. Brunoni, Rodrigo Bressan, Christoph U. Correll, Ary Gadelha   +9 more
doaj   +1 more source

Predictors of Treatment Resistance Across Different Clinical Subtypes of Depression: Comparison of Unipolar vs. Bipolar Cases

Frontiers in Psychiatry, 2020
ObjectiveTreatment-resistant depression (TRD) and treatment-resistant bipolar depression (TRBD) poses a significant clinical and societal burden, relying on different operational definitions and treatment approaches.
Michele Fornaro, Michele Fornaro, Andrea Fusco, Stefano Novello, Pierluigi Mosca, Annalisa Anastasia, Antonella De Blasio, Felice Iasevoli, Andrea de Bartolomeis   +8 more
doaj   +1 more source

Schizophrenia Synaptic Pathology and Antipsychotic Treatment in the Framework of Oxidative and Mitochondrial Dysfunction: Translational Highlights for the Clinics and Treatment

Antioxidants, 2023
Schizophrenia is a worldwide mental illness characterized by alterations at dopaminergic and glutamatergic synapses resulting in global dysconnectivity within and between brain networks.
Giuseppe De Simone, Benedetta Mazza, Licia Vellucci, Annarita Barone, Mariateresa Ciccarelli, Andrea de Bartolomeis   +5 more
doaj   +1 more source

Rational and Translational Implications of D-Amino Acids for Treatment-Resistant Schizophrenia: From Neurobiology to the Clinics

Biomolecules, 2022
Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of schizophrenia treatment and nearly all share the common feature of dopamine
Andrea de Bartolomeis, Licia Vellucci, Mark C. Austin, Giuseppe De Simone, Annarita Barone   +4 more
doaj   +1 more source

Potential efficacy of dopaminergic antidepressants in treatment resistant anergic-anhedonic depression results of the chronic anergic-anhedonic depression open trial – CADOT

Frontiers in Psychiatry, 2023
IntroductionAmong treatment-resistant depression (TRD), we identified anergic-anhedonic clinical presentations (TRAD) as putatively responsive to pro-dopaminergic strategies.
Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Clément de Billy, Clément de Billy, Clément de Billy, Olivier Mainberger, Olivier Mainberger, Olivier Mainberger, Sébastien Weibel, Sébastien Weibel, Sébastien Weibel, Benoit Schorr, Benoit Schorr, Benoit Schorr, Alexandre Obrecht, Alexandre Obrecht, Lionel Landré, Fabrice Berna, Fabrice Berna, Jean-Baptiste Causin, Jean-Baptiste Causin, Jean-Baptiste Causin, Frederic Blanc, Frederic Blanc, Vlad Danila, Vlad Danila, Mihaela Tomsa, Mihaela Tomsa, Geraldine Pfleger, Geraldine Pfleger, Camille Meyer, Camille Meyer, Camille Meyer, Ilia Humbert, Ilia Humbert, Ilia Humbert, Hervé Javelot, Hervé Javelot, Guillaume Meyer, Guillaume Meyer, Gilles Bertschy, Gilles Bertschy, Gilles Bertschy, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher   +47 more
doaj   +1 more source

Patients’ Comprehension of Mindfulness-Based Cognitive Behavioral Therapy in an Outpatient Clinic for Resistant Depression: A Cross-Sectional Study

Frontiers in Psychology, 2019
The current study investigated the comprehension of mindfulness-based cognitive behavioral therapy (MBCT) by patients with resistant depression at the Psychiatry Institute of the Federal University of Rio de Janeiro, Brazil.
Michele F. Rodrigues, Carlos Campos, Luisa Pelucio, Izabel Barreto, Sergio Machado, Jose C. Appolinario, Antonio E. Nardi, Michelle Levitan   +7 more
doaj   +1 more source

Medical cannabis for treatment-resistant combat PTSD

Frontiers in Psychiatry, 2023
Targeting the endocannabinoid system may have a role in the treatment of post-traumatic stress disorder (PTSD). However, few studies have examined the effectiveness of cannabis on symptoms of PTSD, and more research is needed to ascertain cannabis ...
Nitsa Nacasch, Chen Avni, Paz Toren, Paz Toren   +3 more
doaj   +1 more source

Treatment-Resistant Dermatomycoses.

Nippon Ishinkin Gakkai Zasshi, 1998
Dermatomycoses are a common category of fungal infections affecting the skin and subcutaneous tissues. Recent advances in topical and systemic antifungal chemotherapy have provided us with satisfactory results in most of the superficial fungal infections both clinically and mycologically.
T, Matsuda, T, Matsumoto
openaire   +3 more sources

Treatment-resistant hypertension [PDF]

Arhiv za farmaciju, 2022
Treatment-resistant hypertension is one of the most significant causes of poor blood pressure regulation. Patients with resistant hypertension are at a higher risk of developing comorbidities compared to the general hypertensive population. As a result, these patients have an increased incidence of disability and premature death, as well as increased ...
Milošević Maja, Otašević Petar
openaire   +2 more sources

Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia

Frontiers in Psychiatry, 2020
Treatment-resistant schizophrenia (TRS) or suboptimal response to antipsychotics affects almost 30% of schizophrenia (SCZ) patients, and it is a relevant clinical issue with significant impact on the functional outcome and on the global burden of disease.
Andrea de Bartolomeis, Mirko Manchia, Mirko Manchia, Federica Marmo, Licia Vellucci, Felice Iasevoli, Annarita Barone   +6 more
doaj   +1 more source