Results 21 to 30 of about 6,753,495 (314)

Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia

Frontiers in Psychiatry, 2020
Treatment-resistant schizophrenia (TRS) or suboptimal response to antipsychotics affects almost 30% of schizophrenia (SCZ) patients, and it is a relevant clinical issue with significant impact on the functional outcome and on the global burden of disease.
Andrea de Bartolomeis, Mirko Manchia, Mirko Manchia, Federica Marmo, Licia Vellucci, Felice Iasevoli, Annarita Barone   +6 more
doaj   +1 more source

Cognition in Treatment Resistant versus Non- Treatment Resistant Schizophrenia [PDF]

Eur Psychiatry
IntroductionDespite antipsychotic treatment, around one-third of individuals of schizophrenia remain unresponsive.ObjectivesComparing cognitive impairments in TRS versus non-TRS patients.Methods50 adult patients with schizophrenia(DSM-5) were recruited in this cross-sectional cohort study, categorised into TRS (14) (treatment-resistant schizophrenia ...
Shah S, Patel K, Bhandari A, Porwal A, Lalwani N.   +4 more
europepmc   +3 more sources

Prevention And Treatment of Hypertension With Algorithm-based therapy (PATHWAY) number 2:protocol for a randomised crossover trial to determine optimal treatment for drug-resistant hypertension [PDF]

, 2015
INTRODUCTION: Resistant hypertension is inadequately controlled blood pressure (BP) despite treatment with at least three BP-lowering drugs. A popular hypothesis is that resistant hypertension is due to excessive Na(+)-retention, and that 'further ...
Williams, B, Caulfield, M, MacDonald, TM, Cruickshank, JK, MacDonald, Thomas M, Ford, I, Morant, S, Sever, Peter, Webb, David J, Caulfield, Mark, Brown, MJ, McInnes, G, Salsbury, J, Cruickshank, J Kennedy, Williams, Bryan, MacDonald, Thomas M., McInnes, Gordon, Salsbury, Jackie, Morant, Steve, Ford, Ian, Webb, DJ, Brown, Morris J., Cruickshank, J. Kennedy, Webb, David J., Brown, Morris, Sever, P   +25 more
core   +1 more source

Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension. [PDF]

, 2014
Resistant hypertension continues to pose a major challenge to clinicians worldwide and has serious implications for patients who are at increased risk of cardiovascular morbidity and mortality with this diagnosis.
Matson, M, Williams, B, Paton, JF, Kapil, Vikas, Moss, J, Simpson, Iain, Knight, Charles, Poulter, Neil, Poulter, N, Collier, David, de Belder, Mark A, Caulfield, Mark J, Matson, Matthew, Simpson, I, Cleveland, Trevor, Deanfield, John, Lobo, MD, de Belder, MA, Williams, Bryan, Lobo, Melvin D, Moss, Jonathan, Caulfield, MJ, Kapil, V, Knight, C, Paton, Julian F R, Dasgupta, I, Paton, JFR, Deanfield, J, ?, ?, Cleveland, T, Collier, D, Dasgupta, Indranil   +31 more
core   +1 more source

A Decrease in Hemodynamic Response in the Right Postcentral Cortex Is Associated With Treatment-Resistant Auditory Verbal Hallucinations in Schizophrenia: An NIRS Study

Frontiers in Neuroscience, 2022
BackgroundTreatment-resistant auditory verbal hallucinations (TRAVHs) might cause an increased risk of violence, suicide, and hospitalization in patients with schizophrenia (SCZ).
Nana Liang, Sha Liu, Sha Liu, Xinrong Li, Xinrong Li, Dan Wen, Qiqi Li, Yujie Tong, Yong Xu, Yong Xu, Yong Xu   +10 more
doaj   +1 more source

Treatment-Resistant Schizophrenia

Focus, 2020
Although, gratifyingly, research on the treatment of schizophrenia has increasingly focused on first-episode and prodromal patient populations, it is still recognized that many patients with more chronic illnesses exhibit a suboptimal response to treatments.
openaire   +3 more sources

Treatment-Resistant Dermatomycoses.

Nippon Ishinkin Gakkai Zasshi, 1998
Dermatomycoses are a common category of fungal infections affecting the skin and subcutaneous tissues. Recent advances in topical and systemic antifungal chemotherapy have provided us with satisfactory results in most of the superficial fungal infections both clinically and mycologically.
Matsuda, Tetsuo, Matsumoto, Tadahiko
openaire   +3 more sources

Determination of critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against para-aminosalicylic acid with clinical isolates with thyA, folC and dfrA mutations

Annals of Clinical Microbiology and Antimicrobials, 2022
Background & Objectives Accurate determination of antimicrobial resistance profiles is of great importance to formulate optimal regimens against multidrug-resistant tuberculosis (MDR-TB).
Wei Wang, Shanshan Li, Qiping Ge, Haiping Guo, Yuanyuan Shang, Weicong Ren, Yufeng Wang, Zhongtan Xue, Jie Lu, Yu Pang   +9 more
doaj   +1 more source

Treatment-Resistant to Antipsychotics: A Resistance to Everything? Psychotherapy in Treatment-Resistant Schizophrenia and Nonaffective Psychosis: A 25-Year Systematic Review and Exploratory Meta-Analysis

Frontiers in Psychiatry, 2019
Background: Roughly 30% of schizophrenia patients fail to respond to at least two antipsychotic trials. Psychosis has been traditionally considered to be poorly sensitive to psychotherapy.
Daniela Polese, Daniela Polese, Michele Fornaro, Mario Palermo, Vincenzo De Luca, Vincenzo De Luca, Andrea de Bartolomeis   +6 more
doaj   +1 more source

Use of intranasal esketamine in a girl with treatment-resistant depression and autism spectrum disorders

EXCLI Journal : Experimental and Clinical Sciences, 2022
Major depression is a common comorbidity in autism spectrum disorder (ASD), often difficult to identify and to treat. Autistic subjects are more at risk for suicidal thoughts and behaviors compared to typically developing peers.
Miriam Olivola, Vincenzo Arienti, Nicola Bassetti, Serena Civardi, Natascia Brondino   +4 more
doaj   +1 more source