Results 31 to 40 of about 6,753,495 (314)

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]

open access: yes, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney   +41 more
core   +1 more source

The Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor [PDF]

open access: yesIranian Journal of Neonatology, 2019
Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism.
Forod Salehi   +2 more
doaj   +1 more source

Treatment-Resistant Depression in Adolescents: Clinical Features and Measurement of Treatment Resistance

open access: yesJournal of Child and Adolescent Psychopharmacology, 2020
Objective: To describe the clinical characteristics of adolescents with antidepressant treatment-resistant major depressive disorder (MDD) and to examine the utility of the Antidepressant Treatment Record (ATR) in categorizing treatment resistance in this population.
Strawn, Jeffrey R.   +8 more
openaire   +3 more sources

Comparison of Efficacy and Safety Between Low-Dose Ziprasidone in Combination With Sertraline and Ziprasidone Monotherapy for Treatment-Resistant Patients With Acute Exacerbation Schizophrenia: A Randomized Controlled Trial

open access: yesFrontiers in Pharmacology, 2022
Treatment-resistant schizophrenia (TRS) is a prevalent clinical problem with heterogeneous presentations. However, the clinical trial designs for new treatments are still lacking.
Hui Shi   +6 more
doaj   +1 more source

Severe asthma in South Africa: A literature review and management approach for primary care

open access: yesSouth African Family Practice, 2021
Severe asthma in South Africa (SA) is underappreciated, especially in the primary care setting. This study highlights the epidemiological context of severe asthma as a phenotypic variant.
Huibrecht C. Lion-Cachet   +2 more
doaj   +1 more source

Multidrug-resistant tuberculosis. [PDF]

open access: yes, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
Zager, Ellen M, McNerney, Ruth
core   +1 more source

Treatment-Resistant Depression in the Elderly

open access: yesInternational Psychogeriatrics, 1995
Apparent treatment-resistant depression (TRD) is frequently encountered by and poses particular challenges for the old-age psychiatrist. The prevalence of true nonresponse to treatment is not known with accuracy but reports put it at 18% to 40% for the elderly.
D, Bonner, R, Howard
openaire   +2 more sources

Modeling treatment-resistant depression [PDF]

open access: yesNeuropharmacology, 2011
Depression is a polygenic and highly complex psychiatric disorder that is currently a major burden on society. Depression is highly heterogeneous in presentation and frequently exhibits high comorbidity with other psychiatric and somatic disorders. Commonly used treatments, such as selective serotonin reuptake inhibitors (SSRIs), are not ideal since ...
Benjamin Adam, Samuels   +8 more
openaire   +2 more sources

Treatment of drug-resistant tuberculosis

open access: yes, 2011
Lancelot Pinto1,2, Dick Menzies1,21Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, QC, Canada; 2Department of Epidemiology and Biostatistics, McGill University, Montreal, QC, CanadaClinical question: What is the ...
Dick Menzies, Pinto LM, Menzies D
core   +1 more source

The efficacy of antimalarial monotherapies, sulphadoxine-pyrimethamine and amodiaquine in East Africa: implications for sub-regional policy. [PDF]

open access: yes, 2003
Between 1998 and 2001, Kenya, Uganda, Tanzania, Zanzibar, Rwanda and Burundi changed antimalarial drug policy, in the face of widespread chloroquine resistance.
East African Network for Monitoring Antimalarial Treatment (EANMAT)   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy