Results 11 to 20 of about 8,613,368 (310)

Pharmacotherapy for treatment-resistant schizophrenia [PDF]

Neuropsychiatric Disease and Treatment, 2011
Schizophrenia is a disabling mental illness with a lifetime prevalence of 0.7% worldwide and significant, often devastating, consequences on social and occupational functioning. A range of antipsychotic medications are available; however, suboptimal therapeutic response in terms of psychotic symptoms is common and affects up to one-third of people with
Mcilwain, Meghan E, Harrison, Jeff, Wheeler, Amanda J, Russell, Bruce R   +3 more
openaire   +7 more sources

Treatment-resistant prurigo nodularis.

Clinical, cosmetic and investigational dermatology, 2019
Sree S Kolli,1 Wasim Haidari,1 Steven R Feldman1–31Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC, USA; 3Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA ...
Kolli,Sree, Haidari,Wasim, Feldman,Steven   +2 more
openaire   +5 more sources

Schizophrenia Synaptic Pathology and Antipsychotic Treatment in the Framework of Oxidative and Mitochondrial Dysfunction: Translational Highlights for the Clinics and Treatment

Antioxidants, 2023
Schizophrenia is a worldwide mental illness characterized by alterations at dopaminergic and glutamatergic synapses resulting in global dysconnectivity within and between brain networks.
Giuseppe De Simone, Benedetta Mazza, Licia Vellucci, Annarita Barone, Mariateresa Ciccarelli, Andrea de Bartolomeis   +5 more
doaj   +1 more source

Treatment resistance in schizophrenia: a meta-analysis of prevalence and correlates [PDF]

Brazilian Journal of Psychiatry, 2023
Objectives: To determine the prevalence and correlates of treatment-resistant schizophrenia (TRS) through a systematic review and meta-analysis. Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria, an
Elton Diniz, Lais Fonseca, Deyvis Rocha, Alisson Trevizol, Raphael Cerqueira, Bruno Ortiz, André R. Brunoni, Rodrigo Bressan, Christoph U. Correll, Ary Gadelha   +9 more
doaj   +1 more source

Rational and Translational Implications of D-Amino Acids for Treatment-Resistant Schizophrenia: From Neurobiology to the Clinics

Biomolecules, 2022
Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of schizophrenia treatment and nearly all share the common feature of dopamine
Andrea de Bartolomeis, Licia Vellucci, Mark C. Austin, Giuseppe De Simone, Annarita Barone   +4 more
doaj   +1 more source

Potential efficacy of dopaminergic antidepressants in treatment resistant anergic-anhedonic depression results of the chronic anergic-anhedonic depression open trial – CADOT

Frontiers in Psychiatry, 2023
IntroductionAmong treatment-resistant depression (TRD), we identified anergic-anhedonic clinical presentations (TRAD) as putatively responsive to pro-dopaminergic strategies.
Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Clément de Billy, Clément de Billy, Clément de Billy, Olivier Mainberger, Olivier Mainberger, Olivier Mainberger, Sébastien Weibel, Sébastien Weibel, Sébastien Weibel, Benoit Schorr, Benoit Schorr, Benoit Schorr, Alexandre Obrecht, Alexandre Obrecht, Lionel Landré, Fabrice Berna, Fabrice Berna, Jean-Baptiste Causin, Jean-Baptiste Causin, Jean-Baptiste Causin, Frederic Blanc, Frederic Blanc, Vlad Danila, Vlad Danila, Mihaela Tomsa, Mihaela Tomsa, Geraldine Pfleger, Geraldine Pfleger, Camille Meyer, Camille Meyer, Camille Meyer, Ilia Humbert, Ilia Humbert, Ilia Humbert, Hervé Javelot, Hervé Javelot, Guillaume Meyer, Guillaume Meyer, Gilles Bertschy, Gilles Bertschy, Gilles Bertschy, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher   +47 more
doaj   +1 more source

Patients’ Comprehension of Mindfulness-Based Cognitive Behavioral Therapy in an Outpatient Clinic for Resistant Depression: A Cross-Sectional Study

Frontiers in Psychology, 2019
The current study investigated the comprehension of mindfulness-based cognitive behavioral therapy (MBCT) by patients with resistant depression at the Psychiatry Institute of the Federal University of Rio de Janeiro, Brazil.
Michele F. Rodrigues, Carlos Campos, Luisa Pelucio, Izabel Barreto, Sergio Machado, Jose C. Appolinario, Antonio E. Nardi, Michelle Levitan   +7 more
doaj   +1 more source

Diagnosis and Interim Treatment Outcomes from the First Cohort of Multidrug-Resistant Tuberculosis Patients in Tanzania. [PDF]

, 2013
Kibong'oto National Tuberculosis Hospital (KNTH), Kilimanjaro, Tanzania. Characterize the diagnostic process and interim treatment outcomes from patients treated for multidrug-resistant tuberculosis (MDR-TB) in Tanzania.
Kumburu Happiness H., Ndusilo, N.D., Boeree, M.J., Kibiki, Gibson S, Mpagama Stellah G., Kumburu, Happiness H, Houpt, Eric R, Heysell, Scott K, Eric R Houpt, Boeree Martin J., Kisonga, Riziki M, Kibiki, G.S., Nora D Ndusilo, Jean Gratz, Ndusilo Nora D., Riziki M Kisonga, Boeree, Martin J, Lekule Isack A., Stellah G Mpagama, Martin J Boeree, Heysell, S.K., Kisonga Riziki M., Mpagama, Stellah G, Ndusilo, Nora D, Kumburu, H.H., Scott K Heysell, Lekule, Isack A, Gratz, J., Kisonga, R.M., Gratz, Jean, Kibiki Gibson S., Houpt, E.R., Gibson S Kibiki, Heysell Scott K., Mpagama, S.G., Lekule, I.A., Houpt Eric R., Isack A Lekule, Gratz Jean, Happiness H Kumburu   +39 more
core   +2 more sources

Oxaliplatin for the treatment of cisplatin-resistant cancer: a systematic review [PDF]

, 2007
Oxaliplatin is widely regarded as being active in cisplatin-resistant cancer. We undertook a systematic review of the literature to identify, describe and critique the clinical and pre-clinical evidence for the use of oxaliplatin in patients with ...
Pavlakis, Nick, Ross Davey, Davey, Ross, Nick Pavlakis, Britta Stordal, Stordal, Britta, Stordal, B., Pavlakis, N., Davey, R.   +8 more
core   +2 more sources

Medical cannabis for treatment-resistant combat PTSD

Frontiers in Psychiatry, 2023
Targeting the endocannabinoid system may have a role in the treatment of post-traumatic stress disorder (PTSD). However, few studies have examined the effectiveness of cannabis on symptoms of PTSD, and more research is needed to ascertain cannabis ...
Nitsa Nacasch, Chen Avni, Paz Toren, Paz Toren   +3 more
doaj   +1 more source