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Treatment-Resistant Schizophrenia

Psychiatric Clinics of North America, 2016
Although treatment-resistant schizophrenia (TRS) was described 50 years ago and has a gold standard treatment with clozapine based on well-defined criteria, there is still a matter of great interest and controversy. In terms of the underlying mechanisms of the development of TRS, progress has been made for the elucidation of the neurochemical ...
Helio, Elkis, Peter F, Buckley
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Treatment Resistant Hypertension

American Journal of Therapeutics, 2008
Treatment resistant hypertension is defined as a blood pressure not achieving a goal blood pressure (
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Treatment-Resistant Schizophrenia

Psychiatric Clinics of North America, 2007
This article opens with a brief history of pharmacologic treatment of schizophrenia. It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition
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Treatment-Resistant Depression

Psychotherapy and Psychosomatics, 1998
Our ability to treat depression has improved with the availability of receptor-specific and chemically diverse groups of antidepressants. Even now, most of the short-term studies indicate that about 20% of depressed patients remain resistant to treatment. Therefore, it is important to properly assess the treatment-resistant depressed (TRD) patients and
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Treatment-resistant depression and suicidality

Journal of Affective Disorders, 2018
Thirty percent of patients with treatment-resistant depression (TRD) attempt suicide at least once during their lifetime. However, it is unclear what the attempted and completed suicide incidences are in TRD patients after initiating a treatment, and whether specific treatments increase or decrease these incidences.We searched PubMed systematically for
Isidoor O. Bergfeld   +5 more
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