The Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor [PDF]
Iranian Journal of Neonatology, 2019 Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism.
Forod Salehi +2 more
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Treatment resistance in schizophrenia [PDF]
BMJ, 1996 Alternative drugs may offer clearer understanding of underlying mechanisms Since the 1950s, when chlorpromazine was introduced into psychiatric practice, antipsychotic drugs have been the cornerstone of the management of schizophrenia. They have three main functions: to treat the positive symptoms of acute schizophrenic episodes; to reduce ...
E C, Johnstone, R, Sandler
openaire +2 more sources
Soft-tissue abnormalities associated with treatment-resistant and treatment-responsive clubfoot: Findings of MRI analysis [PDF]
, 2014 BACKGROUND: Clubfoot treatment commonly fails and often results in impaired quality of life. An understanding of the soft-tissue abnormalities associated with both treatment-responsive and treatment-resistant clubfoot is important to improving the ...
Aferol, Hyuliya +5 more
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Treatment-Resistant Bipolar Disorder [PDF]
Focus, 2001 Over the last few years, the number of potential pharmacotherapies for bipolar disorder has greatly expanded. Yet the database for virtually all these newer treatments consists of case reports and case series. Among these newer treatments, recently released anticonvulsants are most promising.
openaire +3 more sources
Identifying treatment-resistant schizophrenia [PDF]
British Journal of Psychiatry, 2013 I was surprised to read the paper of Howes et al .[1][1] No control group was investigated. This paper implies that any patient for whom a third antipsychotic is considered ought to be considered for clozapine, and if they are not started on clozapine, this constitutes an unacceptable delay.
Kiriakos, Xenitidis +2 more
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Lamotrigine in the treatment of schizoaffective disorder [PDF]
, 1998 There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Erfurth, Andreas +2 more
core +1 more source
Frontiers in Pharmacology, 2022 Treatment-resistant schizophrenia (TRS) is a prevalent clinical problem with heterogeneous presentations. However, the clinical trial designs for new treatments are still lacking.
Hui Shi +6 more
doaj +1 more source
Comparing the effects of repetitive transcranial magnetic stimulation and electroconvulsive therapy in the treatment of depression : a systematic review and meta-analysis [PDF]
, 2014 Electroconvulsive therapy (ECT) is the longest standing psychiatric treatment available and has unequivocal benefit in severe depression. However this treatment comes with a number of side effects such as memory impairment.
Micallef-Trigona, Beppe
core +4 more sources
Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective survey [PDF]
, 2015 Background Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attaining 17 % higher plasma clozapine ...
Anderson, Simon G. +7 more
core +2 more sources
Severe asthma in South Africa: A literature review and management approach for primary care
South African Family Practice, 2021 Severe asthma in South Africa (SA) is underappreciated, especially in the primary care setting. This study highlights the epidemiological context of severe asthma as a phenotypic variant.
Huibrecht C. Lion-Cachet +2 more
doaj +1 more source