Results 21 to 30 of about 26,546 (243)
Biomedicines, 2023 Clozapine is considered the gold standard for patients with treatment-resistant schizophrenia (TRS) who have previously tried other antipsychotics at adequate doses (two or more, with at least one being atypical).
Vjekoslav Peitl +5 more
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Evaluation of Treatment-Resistant Schizophrenia [PDF]
Schizophrenia Bulletin, 1997 A systematic approach to the evaluation and characterization of treatment resistance in schizophrenia has become increasingly important since the introduction of clozapine, risperidone, and olanzapine. The need for accurate evaluation will increase with the introduction of the next generation of antipsychotic medications.
R R, Conley, R W, Buchanan
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Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019 According to modern data, about a third of patients suffering from schizophrenia are considered treatment resistant. The metabolism of about 20% of medicines and mainly psychotropic drugs is caused by the isoenzyme CYP2D6.
D. N. Sosin +4 more
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Stem Cell Research, 2022 Schizophrenia is a chronic, serious and disabling mental disorder. Most patients can effectively control their condition through drug treatment, but there are still some patients who are difficult to gain benefits from drug treatment.
Jing Sun +7 more
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Clozapine in treatment-resistant schizophrenia [PDF]
British Journal of Psychiatry, 2017 In an era when 11 meta-analyses are published every day, there are sometimes 2 on the same topic which do not agree. As such a situation can be very confusing, systematic reviewers should discuss their findings in the light of existing reviews to make the differences understandable to readers.[1 ...
Myrto, Samara, Stefan, Leucht
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Brazilian Journal of Psychiatry, 2013 Objective: To investigate whether inpatients with disorganized schizophrenia are more resistant to treatment. Method: Eighty-five inpatients were assessed at admission and at discharge for schizophrenia subtype, symptom severity, and treatment ...
Bruno Bertolucci Ortiz +4 more
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European Psychiatry, 2022 Introduction Despite pharmacological advances in the treatment of schizophrenia, significant number of patients are still treatment-resistant. Clozapine is recommended as first-line treatment for treatment-resistant schizophrenia (TRS) in guidelines ...
I. Everte, A. Pamše-Romāne, M. Taube
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Electroconvulsive Therapy for Treatment-Resistant Schizophrenia [PDF]
Schizophrenia Bulletin, 2019 Electroconvulsive therapy (ECT) involves the induction of a seizure by the administration of an electrical stimulus via electrodes usually placed bilaterally on the scalp and was introduced as a treatment for schizophrenia in 1938. However, ECT is a controversial treatment with concerns about long-term side effects such a memory loss.
Diarmid J M, Sinclair +5 more
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Strategies in clozapine-resistant schizophrenia: A literature review
Journal of Mental Health and Human Behaviour, 2016 Treatment resistance to what is often deemed the last line of schizophrenia treatment, clozapine, is a burgeoning problem in psychiatric practice, with estimates of clozapine resistance standing at 40–70% of the treated population.
Ganesh Kundadak Kudva +1 more
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BMC Psychiatry, 2023 Antipsychotic drugs are the first line of treatment in schizophrenia; although antipsychotic responses indicate a wide interindividual variety in patients with schizophrenia.
Narges Taheri +4 more
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