Results 61 to 70 of about 4,914,786 (311)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

S_T_Mamba: A Novel Jinnan Calf Diarrhea Behavior Recognition Model Based on Sequence Tree Mamba

Animals
The efficient and precise recognition of diarrhea-related behaviors in Jinnan calves is crucial for ensuring their healthy development. Nevertheless, conventional behavior recognition techniques are often limited by a notable decline in performance when ...
Wangli Hao, Yakui Xue, Hao Shu, Bingxue Lv, Hanwei Li, Meng Han, Yanhong Liu, Fuzhong Li   +7 more
doaj   +1 more source

A DNA barcoding framework for taxonomic verification in the Darwin Tree of Life Project

Wellcome Open Research
Biodiversity genomics research requires reliable organismal identification, which can be difficult based on morphology alone. DNA-based identification using DNA barcoding can provide confirmation of species identity and resolve taxonomic issues but is ...
A. Twyford, Jordan Beasley, Ian Barnes, Heather Allen, Freja Azzopardi, D. Bell, M. Blaxter, Gavin R. Broad, L. Campos-Domínguez, Darren Choonea, Liam M. Crowley, Piotr Cuber, Michael Cunliffe, Alexandra Dombrowski, Brian Douglas, L. Forrest, Ester Gaya, Clementine Greeves, Claire Griffin, Joanna Harley, Michelle L Hart, Peter W. H. Holland, Peter M. Hollingsworth, Inez Januszczak, Amanda L Jones, Paul J. Kersey, Estelle Kilias, M. Lawniczak, Owen T. Lewis, Sahr Mian, Alice Minotto, Raju Misra, Peter O. Mulhair, Lyndall Pereira da Conceicoa, Benjamin W. Price, Silvia Salatino, Felix Shaw, Olga Sivell, Laura Sivess, Rebekka Uhl, Kieran Woof   +40 more
semanticscholar   +1 more source

Bisection of trees and sequences

Discrete Mathematics, 1993
A bisectable graph \(G\) is the edge-disjoint union of two isomorphic subgraphs. The authors show a quantified version of the fact that any tree with \(e\) edges contains a bisectable subgraph with (asymptotically) almost all edges.
Alon, N., Caro, Y., Krasikov, I.
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Anomaly Detection in Video Sequence With Appearance-Motion Correspondence [PDF]

IEEE International Conference on Computer Vision, 2019
Anomaly detection in surveillance videos is currently a challenge because of the diversity of possible events. We propose a deep convolutional neural network (CNN) that addresses this problem by learning a correspondence between common object appearances
Trong-Nguyen Nguyen, J. Meunier
semanticscholar   +1 more source

Benchmarking tree and ancestral sequence inference for B cell receptor sequences [PDF]

Frontiers in Immunology, 2018
AbstractB cell receptor sequences evolve during affinity maturation according to a Darwinian process of mutation and selection. Phylogenetic tools are used extensively to reconstruct ancestral sequences and phylogenetic trees from affinity-matured sequences. In addition to using general-purpose phylogenetic methods, researchers have developed new tools
Davidsen, Kristian, Matsen IV, Frederick A.   +1 more
openaire   +3 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TREE2FASTA: a flexible Perl script for batch extraction of FASTA sequences from exploratory phylogenetic trees

BMC Research Notes, 2018
Objective The body of DNA sequence data lacking taxonomically informative sequence headers is rapidly growing in user and public databases (e.g. sequences lacking identification and contaminants).
Thomas Sauvage, Sophie Plouviez, William E. Schmidt, Suzanne Fredericq   +3 more
doaj   +1 more source

Functional Classification of Super-Large Families of Enzymes Based on Substrate Binding Pocket Residues for Biocatalysis and Enzyme Engineering Applications

Frontiers in Bioengineering and Biotechnology, 2021
Large enzyme families such as the groups of zinc-dependent alcohol dehydrogenases (ADHs), long chain alcohol oxidases (AOxs) or amine dehydrogenases (AmDHs) with, sometimes, more than one million sequences in the non-redundant protein database and ...
Fernanda L. Sirota, Sebastian Maurer-Stroh, Sebastian Maurer-Stroh, Zhi Li, Frank Eisenhaber, Frank Eisenhaber, Frank Eisenhaber, Birgit Eisenhaber, Birgit Eisenhaber   +8 more
doaj   +1 more source