Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia [PDF]
Journal of Diabetes Research, 2020 Ischemic postconditioning (PC) is proved to efficiently protect diabetic patients with acute myocardial infarction from ischemia-reperfusion injury.
Ling Zhao +5 more
doaj +5 more sources
Comparing the hippocampal miRNA expression profiles of wild and domesticated Chinese tree shrews (Tupaia belangeri chinensis) [PDF]
BMC Ecology and Evolution, 2021 Background The domestication of tree shrews represents an important advance in the development of standardized laboratory animals. Little is known regarding the miRNA changes that accompany the transformation of wild tree shrews into domestic tree shrews.
Caixia Lu +6 more
doaj +3 more sources
Technical advance: The use of tree shrews as a model of pulmonary fibrosis. [PDF]
PLoS ONE, 2020 BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with a high morbidity and mortality. Some of the mechanisms of fibrosis development have been described using rodent models; however, the relevance of findings in these ...
Jennifer L Larson-Casey +9 more
doaj +3 more sources
Comparative Pathogenicity and Transmissibility of Pandemic H1N1, Avian H5N1, and Human H7N9 Influenza Viruses in Tree Shrews [PDF]
Frontiers in Microbiology, 2019 Influenza A viruses (IAVs) continuously challenge the poultry industry and human health. Studies of IAVs are still hampered by the availability of suitable animal models.
Shuai Xu +7 more
doaj +3 more sources
Involvement of dopamine D3 receptor and dopamine transporter in methamphetamine-induced behavioral sensitization in tree shrews. [PDF]
Brain Behav, 2020 This study aims to establish a methamphetamine (METH)‐induced behavioral sensitization model using tree shrews, as well as to measure the protein expression of the dopamine D3 receptor (D3R) and dopamine transporter (DAT).
Huang J +11 more
europepmc +4 more sources
Response of the gut microbiota during the Clostridioides difficile infection in tree shrews mimics those in humans [PDF]
BMC Microbiology, 2020 Background Clostridioides difficile is a major cause of antibiotic associated diarrhea. Several animal models are used to study C. difficile infection (CDI). The tree shrew has recently been developed as a model of primate processes. C.
Wenpeng Gu +12 more
doaj +3 more sources
Comparative genomic analysis of Proteus spp. isolated from tree shrews indicated unexpectedly high genetic diversity. [PDF]
PLoS ONE, 2020 Proteus spp. are commensal gastrointestinal bacteria in many hosts, but information regarding the mutual relationships between these bacteria and their hosts is limited.
Wenpeng Gu +10 more
doaj +3 more sources
The effects of intensity, spectral purity and duty cycle on red light-induced hyperopia in tree shrews. [PDF]
Ophthalmic Physiol Opt, 2023 There have recently been several clinical studies suggesting that brief periods of exposure to red light (repeated low‐level red light, ‘RLRL’) may produce a dramatic anti‐myopia effect, calling for further investigations into its therapeutic parameters.
Gawne TJ, Samal AV, She Z.
europepmc +2 more sources
The Tree Shrew as a Model for Cancer Research [PDF]
Frontiers in Oncology, 2021 Animal disease models are necessary in medical research, and an appropriate animal model is of great importance for studies about the prevention or treatment of cancer.
Tao Lu +6 more
doaj +2 more sources
Amber light treatment produces hyperopia in tree shrews. [PDF]
Ophthalmic Physiol Opt, 2021 Exposure to narrow‐band red light, which stimulates only the long‐wavelength sensitive (LWS) cones, slows axial eye growth and produces hyperopia in tree shrews and macaque monkeys. We asked whether exposure to amber light, which also stimulates only the
Khanal S, Norton TT, Gawne TJ.
europepmc +2 more sources