Comparing the hippocampal miRNA expression profiles of wild and domesticated Chinese tree shrews (Tupaia belangeri chinensis) [PDF]
BMC Ecology and Evolution, 2021 Background The domestication of tree shrews represents an important advance in the development of standardized laboratory animals. Little is known regarding the miRNA changes that accompany the transformation of wild tree shrews into domestic tree shrews.
Caixia Lu +6 more
doaj +2 more sources
Tree shrews (tupaia belangeri) exhibit novelty preference in the novel location memory task with 24-hour retention periods. [PDF]
Frontiers in Psychology, 2014 Novelty preference is pervasive in mammalian species, and describes an inherent tendency to preferentially explore novelty. The novel location memory task studied here assesses the ability of animals to form accurate memories of a spatial configuration,
Jayakrishnan H R Nair +8 more
doaj +3 more sources
Natural Hepacivirus Infection in Tree Shrews: A Call for Routine Screening in Hepatitis Virus Research [PDF]
VirusesHepatitis viruses continue to pose major global health challenges, necessitating the development of reliable and well-characterized experimental models.
Mohammad Enamul Hoque Kayesh +3 more
doaj +2 more sources
Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia [PDF]
Journal of Diabetes Research, 2020 Ischemic postconditioning (PC) is proved to efficiently protect diabetic patients with acute myocardial infarction from ischemia-reperfusion injury.
Ling Zhao +5 more
doaj +2 more sources
Technical advance: The use of tree shrews as a model of pulmonary fibrosis. [PDF]
PLoS ONE, 2020 BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with a high morbidity and mortality. Some of the mechanisms of fibrosis development have been described using rodent models; however, the relevance of findings in these ...
Jennifer L Larson-Casey +9 more
doaj +2 more sources
Comparative Pathogenicity and Transmissibility of Pandemic H1N1, Avian H5N1, and Human H7N9 Influenza Viruses in Tree Shrews [PDF]
Frontiers in Microbiology, 2019 Influenza A viruses (IAVs) continuously challenge the poultry industry and human health. Studies of IAVs are still hampered by the availability of suitable animal models.
Shuai Xu +7 more
doaj +2 more sources
Response of the gut microbiota during the Clostridioides difficile infection in tree shrews mimics those in humans [PDF]
BMC Microbiology, 2020 Background Clostridioides difficile is a major cause of antibiotic associated diarrhea. Several animal models are used to study C. difficile infection (CDI). The tree shrew has recently been developed as a model of primate processes. C.
Wenpeng Gu +12 more
doaj +2 more sources
A study on the establishment of a traumatic brain injury model of tree shrews and the observation of neuroinflammatory responses [PDF]
IBRO Neuroscience ReportsBackground and objective: The tree shrew (Tupaia belangeri) has become an ideal model for studying various neurological diseases. However, there is no stable tree shrew model of traumatic brain injury (TBI) at present.
Wen Yu +10 more
doaj +2 more sources
Washed Microbiota Transplantation Accelerates the Recovery of Abnormal Changes by Light-Induced Stress in Tree Shrews [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 The gut and brain interact constantly in a complex fashion. Its intricacy and intrigue is progressively being revealed in the study of the “gut–brain axis”.
Jing Wang +14 more
doaj +2 more sources
Comparative genomic analysis of Proteus spp. isolated from tree shrews indicated unexpectedly high genetic diversity. [PDF]
PLoS ONE, 2020 Proteus spp. are commensal gastrointestinal bacteria in many hosts, but information regarding the mutual relationships between these bacteria and their hosts is limited.
Wenpeng Gu +10 more
doaj +2 more sources