Results 41 to 50 of about 3,818 (288)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Genetic variability studies in selected genotypes of khirni (Manilkara hexandra)

Electronic Journal of Plant Breeding
Khirni is one of the minor fruit crop of tropics. It is a well–known for medicinal and commercial importance. Totally, twenty six khirni genotypes were evaluated for yield, yield contributing characters and bio-chemical features during 2022-2023 at ...
Shashwat P. Mahalle1*, G. G. Jadhav2, U. A. Raut1, S. G. Bharad1, A. D. Ingole3 and N. A. Khairkar1
doaj   +1 more source

Orchard performance and fruit quality of 50 apple cultivars grown or tested in commercial orchards of the Czech Republic

Horticultural Science, 2007
Tree vigour, occurrence of mildew and scab, yields, yield efficiency, fruit weight, flesh firmness and soluble solids content of apple trees on M 9 rootstock were monitored between 1998-2005 in 42 commercial orchards situated in all the major growing ...
J. Blažek, I. Hlušičková
doaj   +1 more source

Impact of heavy pruning on development and photosynthesis of Tilia cordata Mill. trees.

PLoS ONE, 2021
Tree pruning is carried out to reduce conflict with infrastructure, buildings, and any other human activity. However, heavy pruning may result in a diminished tree crown capacity for sugar production and exposure to fungal infection. This risk leads to a
Marzena Suchocka, Tatiana Swoczyna, Joanna Kosno-Jończy, Hazem M Kalaji   +3 more
doaj   +1 more source

Effect of cultivar, tree vigour and fruit position on calcium accumulation in avocado fruits [PDF]

Scientia Horticulturae, 1990
Abstract The seasonal trends of calcium (Ca) in cultivars ‘Fuerte’ and ‘Hass’ avocado fruits from vigorous and non-vigorous trees with little and moderate root infection by Phytophthora cinnamomi , respectively, were studied. The Ca concentration increased in all fruit until 6 weeks after fruit set, but then decreased rapidly until ∼16 weeks.
G.W. Witney, P.J. Hofman, B.N. Wolstenholme   +2 more
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A comparison of initial harvest results from four partial harvest systems at the Blue Heron Demonstration Forest

The Forestry Chronicle
Demonstration forests have been established across the northern hardwoods of the United States to assess the economic and environmental implications of partial harvest systems, such as single tree selection and diameter limit cutting.
Malcolm Cecil-Cockwell, Adam Gorgolewski, John Caspersen, Thomas McCay   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Identifying vigour controlling rootstocks for mango

, 2018
Vigour reduction in many tree crops is an essential element of highly productive, high density systems that is often achieved through rootstocks. Mangoes are large vigorous tropical trees that are traditionally grown at low density as suitable vigour ...
Mizani, A, Wright, C, Kolala, R, Bally, I, Ibell, P. T., Maddox, Cheryl, Bally, I., Bally, Ian S.E., Ibell, Paula, Wright, Carole L., Mizani, A., Ibell, PT, Kolala, R., Maddox, C, Wright, C., Maddox, C.   +15 more
core   +1 more source