Results 221 to 230 of about 122,409 (259)

AN IRRADIATION-FREE PROTOCOL FOR MIXED CHIMERISM AND TOLERANCE THROUGH TREG-THERAPY

, 2008
Nina Pilat, Ulrike Baranyi, Christoph Klaus, Elmar Jaeckel, Nonsikelelo Mpofu, Ferdinand Muehlbacher, Thomas Wekerle   +6 more
openalex   +1 more source

Blocking ITGA5 potentiates the efficacy of anti‐PD‐1 therapy on glioblastoma by remodeling tumor‐associated macrophages

Cancer Communications, EarlyView.
Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao, Ziwen Pan, Jiawei Qiu, Boyan Li, Yanhua Qi, Zijie Gao, Wei Qiu, Weijie Tang, Xiaofan Guo, Lin Deng, Gang Li, Hao Xue   +11 more
wiley   +1 more source

Therapeutic effect of miR-30b-5p-loaded lentivirus on experimental autoimmune uveitis via inhibiting Notch signaling activation. [PDF]

J Transl Med
Yin X, Wei H, Guo L, Liu B, Peng Y, Zhou M, Qiu Y, Qu R, Gao Y, Wu Q, Jiang W, Bi H, Guo D.   +12 more
europepmc   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Comparison of Regulatory T-Cell Subpopulations in Antithymocytic Globulin Versus Post-Transplant Cyclophosphamide for Preventing Graft-Versus-Host Disease in Allogeneic Hematopoietic Stem Cell Transplantation-A Retrospective Study. [PDF]

Int J Mol Sci
Heo BY, Koh JS, Choi SY, Pham TTD, Lee SW, Park JH, Jang Y, Lee MW, Lee SB, Seo W, Jo DY, Kwon J, Song IC.   +12 more
europepmc   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

The immunology of diabetic cardiomyopathy. [PDF]

Front Endocrinol (Lausanne)
Song M, Dai H, Zhou Q, Meng X.
europepmc   +1 more source

Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis

, 2008
Derek A Holmes, Qi Jiang, Liguo Zhang, Lishan Su   +3 more
openalex   +2 more sources

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

High Antigenicity for T_reg Cells Confers Resistance to PD-1 Blockade Therapy via High PD-1 Expression in T_reg Cells. [PDF]

Cancer Sci
Matsuura H, Ishino T, Ninomiya T, Ninomiya K, Tachibana K, Honobe-Tabuchi A, Muto Y, Inozume T, Ueda Y, Ohashi K, Maeda Y, Nagasaki J, Togashi Y.   +12 more
europepmc   +1 more source