Results 241 to 250 of about 156,448 (312)

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Metadomain and metaloop genome interactions in mammalian T cells. [PDF]

Cell Rep
Dolsten G, Wang ZM, Huang X, Song S, Wilson MJ, Bing XY, Ke W, Cafiero TR, Nelson AN, Fernando S, Ploss A, Schedl P, Levine MS, Viny AD, Rudensky AY, Pritykin Y.   +15 more
europepmc   +1 more source

Single‐Cell Profiling Reveals Distinct Immune Hallmarks in Untreated Primary Colorectal and Liver Metastasis Cancers

Chronic Diseases and Translational Medicine, EarlyView.
Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao, Haipeng Chen, Xu Guan, Zheng Jiang, Zheng Liu, Ming Yang, Hengchang Liu, Tianli Chen, Shuangmei Zou, Yibo Gao, Xishan Wang   +10 more
wiley   +1 more source

Regulatory T cells in bullous pemphigoid: biological characteristics, dysfunction, and pathogenic roles. [PDF]

Front Immunol
Wang Z, Lu Y, Cui H, Zhang Y, Meng L, Chang W, Yang X, Ye J.   +7 more
europepmc   +1 more source

Molecular hydrogen is associated with immunophenotypic modulation and changes in T-cell exhaustion markers in refractory primary Sjögren's syndrome-associated interstitial lung disease: A case report. [PDF]

SAGE Open Med Case Rep
Hsu WH, Lu JW, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC.   +6 more
europepmc   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

AI-based pathomics model predicts regulatory T cell infiltration and radiotherapy response in IDH-wild-type glioblastoma. [PDF]

Front Immunol
Peng S, Chen J, Wang X, Wang X, Yue Q, Lan H, Zhang J, Xie Y, Yang M, Xiao J, Guo C, Wang Y, Wu Z, Hong J, Zhang M.   +14 more
europepmc   +1 more source

OMIP‐121: Immune Phenotyping of Canine Peripheral Leukocytes by Mass Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Dogs are a critical non‐rodent species used in preclinical safety studies, particularly, in the pharmaceutical field, due to their physiological, metabolic, and immunological similarities to humans. As such, immunophenotyping of canine peripheral blood mononuclear cells (PBMCs) plays a crucial role in translational research, immune monitoring,
Huyen Thuc Tran Luong, Dominique Revets, Sofie Vercammen, Ario de Marco, Hilde de Rooster, Antonio Cosma   +5 more
wiley   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Metabolic adaptations of immunosuppressive cells in cancer: mechanisms and therapeutic targets. [PDF]

Exp Mol Med
Kim J, Shin JM, Um Y, Yuan S, Lim SA.
europepmc   +1 more source