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Treg Cell-Based Therapies: Challenges and Perspectives [PDF]

Nature Reviews Immunology, 2020
Cellular therapies using regulatory T (Treg) cells are currently undergoing clinical trials for the treatment of autoimmune diseases, transplant rejection and graft-versus-host disease.
Caroline Raffin, Jeffrey Bluestone
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Expansion of Tumor-Associated Treg Cells Upon Disruption of a CTLA-4-Dependent Feedback Loop

Cell, 2021
Shivashankar Othy, Thorsten R Mempel, Vinidhra Mani   +2 more
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Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

Frontiers in Immunology, 2021
Fatma Saaoud, Hong Wang
exaly  

Engineered Treg Cells as Putative Therapeutics Against Inflammatory Diseases and Beyond

Trends in Immunology, 2023
Markus Feuerer
exaly  

Signals of Pseudo-Starvation Unveil the Amino Acid Transporter SLC7A11 as Key Determinant in the Control of Treg Cell Proliferative Potential

Immunity, 2021
Silvia Garavelli, Danila Vella, Mario Galgani   +2 more
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Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Cell Metabolism, 2020
Erika L. Pearce, Michael Loschi, Keli L Hippen   +2 more
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