Results 181 to 190 of about 93,800 (248)

TREG cell therapy [PDF]

Nature Reviews Rheumatology, 2010
openaire   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

The immunobiology and therapeutic potential of regulatory T cells in autoimmune diseases and allergic diseases. [PDF]

Front Immunol
Xie WW, Huang JB, Zhou YC, Yuan JY, Feng JX, Shi XH, Tian L, Zeng XH, Qiu SQ, Zhao MZ, Cheng BH, Zeng HT.   +11 more
europepmc   +1 more source

Muscular Treg cells [PDF]

Nature Medicine, 2014
openaire   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

Advanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu, Huiyuan Ma, Tinghui Zhu, Shuwei Huang, Manxi Lu, Qiong Wang, Zai‐Long Chi   +6 more
wiley   +1 more source

Myeloid-derived suppressor cells and regulatory T cells in colorectal cancer: a synergistic immunosuppressive axis and emerging therapeutic opportunities. [PDF]

Front Immunol
Zhang W, Jin C, Liu S, Wan X, Li Y, Liu J, Duan Z, Ma J, Gao Y.   +8 more
europepmc   +1 more source

Pharmacokinetics of Therapeutic Tregs

American Journal of Transplantation, 2014
openaire   +2 more sources

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

Regulatory T-cell sensing of extracellular ATP via P2RX7 promotes their accumulation and suppression and drives lung tumor growth. [PDF]

Cancer Immunol Res
Santiago-Carvalho I, Francisco R, de Gois Macedo B, Salgado CL, Stoll CR, Shao S, Beniwal A, Kwok T, Banuelos A, Cione MP, White E, Johnston TM, Leff CL, Silva-Junior I, Carvalho de Souza F, Thant W, Pandya P, D'Imperio Lima MR, Fernandez-Bussy S, Abia-Trujillo D, Vu LH, Tran NL, Husta BC, Copland JA, Gounari F, Justilien V, Lancaster JN, Borges da Silva H.   +27 more
europepmc   +1 more source