Results 181 to 190 of about 130,982 (298)

Identifying TNFSF4^low-MSCs superiorly treating idiopathic pulmonary fibrosis through Tregs differentiation modulation. [PDF]

Stem Cell Res Ther
Xie Y, Yi Q, Xu C, Wang Y, Jiang Y, Feng Y, Wang L, Yang H, Zhang Y, Wang B.   +9 more
europepmc   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, Volume 12, Issue 17, May 8, 2025.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source

Prognostic values of regulatory T cells (Tregs) and Treg-related genes in gastric cancer

Central European Journal of Immunology, 2023
Liang Zheng, Luping Lin, Jintian Song, Sha Huang, Lizhu Chen, Hui Li, Ning Ma, Qingyue Chen, Yigui Chen   +8 more
doaj   +1 more source

The aryl hydrocarbon receptor: a regulator of Th17 and Treg cell development in disease [PDF]

, 2008
Peggy P. Ho, Lawrence Steinman
openalex   +1 more source

Regulatory T cells: a promising new therapeutic target in ventricular remodeling after myocardial infarction. [PDF]

Front Immunol
Qin Y, Li M, Liu H.
europepmc   +1 more source

A Spleen‐Targeted Tolerogenic mRNA‐LNPs Vaccine for the Treatment of Experimental Asthma

Advanced Science, Volume 12, Issue 13, April 3, 2025.
Splenic DCs‐targeted co‐delivery of nucleoside‐modified antigen mRNA and Cel‐loaded LNPs vaccine induces tolerogenic DCs and subsequent antigen‐specific CD4+ regulatory T cells for the treatment of experimental allergic asthma. Abstract Lipid nanoparticles (LNPs)‐based mRNA vaccines have witnessed their great advantages in the fight against infectious ...
Fazhan Wang, Jia Lou, Xiaohan Lou, Fang Wu, Xiaoke Gao, Xiaohan Yao, Jiajia Wan, Xixi Duan, Wenjing Deng, Lixia Ma, Lijing Zhang, Guangjie He, Ming Wang, Chen Ni, Ningjing Lei, Zhihai Qin   +15 more
wiley   +1 more source

Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus [PDF]

, 2008
Timothy Kottke, Feorillo Galivo, Phonphimon Wongthida, Rosa María Díaz, Jill Thompson, Dragan Jevremović, Glen N. Barber, Geoff Hall, John Chester, Peter J. Selby, Kevin J. Harrington, Alan Melcher, Richard G. Vile   +12 more
openalex   +1 more source

Regulatory T cells in solid tumor immunotherapy: effect, mechanism and clinical application. [PDF]

Cell Death Dis
Pan Y, Zhou H, Sun Z, Zhu Y, Zhang Z, Han J, Liu Y, Wang Q.   +7 more
europepmc   +1 more source

Novel immunotherapies for immune-mediated haemolytic anaemia in dogs and people [PDF]

, 2015
Aerts, Ahmad, Andre, Baek, Baker, Baluna, Barcellini, Bardwell, Barker, Barker, Barker, Bennett, Berentsen, Bielekova, Brode, Brunkow, Buckner, Cancro, Cao, Castela, Corato, Den Otter, Desreumaux, Dieckmann, Dowling, Ellis, Forrester, Gagliani, Garden, Ginzler, Graca, Grant, Grundy, Haagsman, Haase, Hall, Hall, Han, Herzog, Heylmann, Hoffmann, Hori, Hori, Humrich, Impellizeri, Ito, James W Swann, Jubala, Jutel, Keiserman, Kim, Klatzmann, Knueppel, Kojima, Komatsu, Konietschke, Lutz, Mahevas, Mahevas, Marek-Trzonkowska, Mason, McCullough, Meiler, Miller, Miyara, Mouchess, Moyo, Mqadmi, Mueller, Oliver A Garden, Olivry, Packman, Penalver, Pinheiro, Polyak, Putnam, Reff, Reimer, Reynaud, Ring, Rodriguez, Rose, Rosenstein, Rue, Saadoun, Sabatos-Peyton, Sadlack, Sadlack, Sakaguchi, Schabowsky, Sharfe, Singer, Swann, Swann, Thornton, Tischner, Verhagen, Volkmann, Waldron-Lynch, Ward, Whitley, Wildin, Willerford, Wing, Xiao, Xu, Xu, Yadav, Zaja, Zanella, Zhao, Ziekman   +111 more
core   +1 more source

Targeting USP1 Potentiates Radiation‐Induced Type I IFN‐Dependent Antitumor Immunity by Enhancing Oligo‐Ubiquitinated SAR1A‐Mediated STING Trafficking and Activation

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Targeting USP1 is identified as a strategy that significantly enhances type I IFN‐dependent innate immune response within the TME following radiotherapy. Mechanistically, USP1 inhibition facilitates STING trafficking from ER to Golgi by preserving K27‐linked oligo‐ubiquitination of SAR1A, thereby facilitating efficient activation of the dsDNA‐cGAS ...
Weilin Zhou, Yuxuan Zhao, Wenjing Qin, Weijian Wu, Chenyang Liao, Yiqiu Zhang, Xingli Yang, Xue Chen, Youqiao Wang, Yushan Kang, Jiaxin Wu, Jiaojiao Zhao, Junmin Quan, Xuecen Wang, Xianzhang Bu, Xin Yue   +15 more
wiley   +1 more source