Results 211 to 220 of about 130,982 (298)

CD73 promotes the immunoregulatory functions of hepatic Tregs through enzymatic and nonenzymatic pathways in MASLD development. [PDF]

Mol Metab
Jin H, Zhong X, Zhang C, Wu Y, Sun J, Wang X, Wang Z, Zhu J, Jiang Y, Du X, Zhang Z, Zhang D, Sun G.   +12 more
europepmc   +1 more source

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

Advanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu, Weichen Xu, Xuexia Shan, Liping Sun, Shuo Liu, Xixi Sun, Shaoyue Li, Xiaodong Hou, Xiaowan Bo, Chengzhong Peng, Bin Huang, Huixiong Xu, Wenwen Yue   +12 more
wiley   +1 more source

The role of Treg cells in colorectal cancer and the immunotherapy targeting Treg cells. [PDF]

Front Immunol
Yu H, Yang R, Li M, Li D, Xu Y.
europepmc   +1 more source

Prevalence of FoxP3+ Cells in Canine Tumours and Lymph Nodes Correlates Positively with Glucose Transporter 1 Expression [PDF]

, 2016
A. Hibbert, Abbondati, Airley, Ben-Shoshan, Brizel, Brown, Brown, Brusko, Bussink, Campbell, Ciaraldi, Clambey, Clarke, Coffer, Comerford, Deng, Deng, Duechler, Eltzschig, Facciabene, Falanga, Fenton, Freyer, Fu, Grau, Gray, H.M. Martineau, Haber, Haney, Hansen, Höckel, Höckel, Imtiyaz, Ishida, J. Relf, Josefowicz, Kallio, Kim, Kinoshita, Koch, Konerding, L. Fortuna, Liyanage, Luoto, Mantovani, Medina, Neildez-Nguyen, Nishikawa, Noman, O.A. Garden, Oh, Ozgur, Pennacchietti, Petty, Pinheiro, Rudlowski, Sakoda, Scholz, Secomb, Skinner, Snyder, Thornton, Vaupel, Wang, Wang, Y.-M. Chang, Yan, Younes   +67 more
core   +2 more sources

The Innate Immune Sensor Zbp1 Mediates Central Nervous System Inflammation Induced by Angiostrongylus Cantonensis by Promoting Macrophage Inflammatory Phenotypes

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This study reveals that Zbp1 plays a pivotal role in regulating neuroimmune interactions during Angiostrongylus cantonensis (AC) infection. Zbp1 modulates lymphocyte infiltration and natural killer (NK) cell cytotoxicity by promoting cytokine secretion and M1 polarization of macrophages, shaping the CNS immune microenvironment.
Hongli Zhou, Minyu Zhou, XiPing Liao, Liangyu Zhang, Hang Wei, Yuting Lu, Yiqing Zhang, Hui Huang, Yue Hu, Tao Chen, Zhiyue Lv   +10 more
wiley   +1 more source

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes [PDF]

, 2009
Madhav Sharma, De-Yan Hou, Yanjun Liu, Pandelakis A. Koni, Richard Metz, Phillip Chandler, Andrew L. Mellor, Yukai He, David H. Munn   +8 more
openalex   +1 more source

CCR9 shapes the immune microenvironment of colorectal cancer modulating the balance between intratumoral CD8+ T cell and FoxP3+ Helios+ Treg subpopulations. [PDF]

PLoS One
Martínez-Ríos J, López-Pacheco CP, García-Zepeda EA, Soldevila G.   +3 more
europepmc   +1 more source

A CLDN18.2‐Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer

Advanced Science, Volume 12, Issue 16, April 24, 2025.
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang, Hui Hui, Jing Han, Ting Guo, Yiding Wang, Lin Meng, Cong Chen, Jie He, Xiaoyong Guo, Fuyu Zhong, Hong Du, Jie Tian, Xiaofang Xing, Yang Du, Jiafu Ji   +14 more
wiley   +1 more source

Myeloid‐derived suppressor cells (MDSCs) and tumor‐associated macrophages (TAMs) produce CCL22 which selectively recruits regulatory T‐cells (Tregs) to the tumor microenvironment

, 2008
Adam W. Mailloux, Matthew R. Young
openalex   +1 more source

Induction of Treg by monocyte‐derived DC modulated by vitamin D₃ or dexamethasone: Differential role for PD‐L1 [PDF]

, 2009
Wendy W. J. Unger, Sandra Laban, Fleur S. Kleijwegt, Arno R. van der Slik, Bart O. Roep   +4 more
openalex   +1 more source