Results 221 to 230 of about 93,800 (248)
B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes. [PDF]
DiabetesWilson CS, Stocks BT, Falk AC, Moore DJ.
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Protein-level profiling of TIGIT axis components in human PDAC reveals immune-suppressive expression patterns. [PDF]
Cancer Immunol ImmunotherQuatannens D +17 more
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Restoring B cell intrinsic tolerance to lupus autoimmunity: a rational strategy for lupus treatment. [PDF]
Front ImmunolShai SD +6 more
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Hyaluronic acid-CD44 signaling defines therapeutic resistance and immunosuppressive microenvironment in peritoneal metastasis of gastric cancer. [PDF]
J Immunother CancerZhao J +18 more
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Molecular Biology Reports, 2021
Atherosclerosis involves both innate and adaptive immunity. Here, we provide an overview of the role of regulatory T (Treg) cells in atherosclerotic diseases. Treg cells and their inhibitory cytokines, IL-10 and TGF-β, have been identified in atherosclerotic lesions and to inhibit progression through lipoprotein metabolism modulation.
Rebecca Kuan +2 more
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Atherosclerosis involves both innate and adaptive immunity. Here, we provide an overview of the role of regulatory T (Treg) cells in atherosclerotic diseases. Treg cells and their inhibitory cytokines, IL-10 and TGF-β, have been identified in atherosclerotic lesions and to inhibit progression through lipoprotein metabolism modulation.
Rebecca Kuan +2 more
openaire +2 more sources
Annals of the Rheumatic Diseases, 2010
Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms.
M, Bonelli, J S, Smolen, C, Scheinecker
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Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms.
M, Bonelli, J S, Smolen, C, Scheinecker
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Current Opinion in Organ Transplantation, 2012
Transfer of human regulatory T cells (Tregs) has become an attractive therapeutic alternative to improve the long-term outcome in transplantation and thus reduce the side-effects of conventional immunosuppressive drugs. Here, we summarize the recent findings on human Treg subsets, their phenotype and in-vivo function.In the last 2 years, it has become ...
Ulrike Schlieer +2 more
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Transfer of human regulatory T cells (Tregs) has become an attractive therapeutic alternative to improve the long-term outcome in transplantation and thus reduce the side-effects of conventional immunosuppressive drugs. Here, we summarize the recent findings on human Treg subsets, their phenotype and in-vivo function.In the last 2 years, it has become ...
Ulrike Schlieer +2 more
openaire +2 more sources
Differentiation of Peripheral Treg
2022This chapter shows protocols for the differentiation of peripheral Treg (pTreg) from polyclonal and monoclonal CD4+ T cells. Polyclonal naïve CD4+ T cells can differentiate into pTreg upon adoptive transfer into Foxp3-diphtheria toxin receptor transgenic recipient mice in which endogenous Tregs are transiently depleted by administration of diphtheria ...
José, Almeida-Santos +2 more
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2021
Uveitis is a chronic disease with relapsing and remitting ocular attack, which requires corticosteroids and systemic immunosuppression to prevent severe vision loss. Classically, uveitis is referred to an autoimmune disease, mediated by pro-inflammatory Th17 cells and immunosuppressive CD4+CD25+FoxP3+ T-regulatory cells (Tregs).
Zhaohao, Huang, Wenli, Li, Wenru, Su
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Uveitis is a chronic disease with relapsing and remitting ocular attack, which requires corticosteroids and systemic immunosuppression to prevent severe vision loss. Classically, uveitis is referred to an autoimmune disease, mediated by pro-inflammatory Th17 cells and immunosuppressive CD4+CD25+FoxP3+ T-regulatory cells (Tregs).
Zhaohao, Huang, Wenli, Li, Wenru, Su
openaire +2 more sources