Results 51 to 60 of about 99,148 (259)

Characterising the role of GABA and its metabolism in the wheat pathogen Stagonospora nodorum [PDF]

, 2015
A reverse genetics approach was used to investigate the role of γ-aminobutyric acid metabolism in the wheat pathogenic fungus Stagonospora nodorum. The creation of mutants lacking Sdh1, the gene encoding succinic semialdehyde dehydrogenase, resulted in ...
Mead, Oliver, Solomon, Peter S., Thynne, Eli, Winterberg, Britta   +3 more
core   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus type 2 replication.

PLoS Pathogens
Trehalose is a non-reducing disaccharide that is the major sugar found in insect hemolymph fluid. Trehalose provides energy, and promotes growth, metamorphosis, stress recovery, chitin synthesis, and insect flight.
Andrew D Marten, Douglas P Haslitt, Chad A Martin, Akshitha Karthikeyan, Daniel H Swanson, Karishma Kalera, Ulysses G Johnson, Benjamin M Swarts, Michael J Conway   +8 more
doaj   +1 more source

The role of trehalose metabolism in plant stress tolerance

Journal of Advanced Research
Background: Trehalose is a nonreducing disaccharide containing two glucose molecules linked through an α,α-1,1-glycosidic bond. This unique chemical structure causes trehalose levels to fluctuate significantly in plants under stress, where it functions ...
Tong-Ju Eh, Yaxuan Jiang, Mingquan Jiang, Jianxin Li, Pei Lei, Ximei Ji, Hyon-Il Kim, Xiyang Zhao, Fanjuan Meng   +8 more
doaj   +1 more source

An investigation on interaction between trehalose and ascorbic acid on some growth parameters and photosynthetic gene expression in Arabidopsis thaliana seedlings [PDF]

Zīst/shināsī-i Giyāhī-i Īrān, 2014
Trehalose is an α-α linked glucose disaccharide. Trehalose supplied to the growth medium of Arabidopsis seedlings inhibits root growth, primary leaf development and carbon allocation from shoot to root.
Hamid Sadeghipour, Mahnaz Aghdasi, Nadia Rezaeean, Mahnaz Aghdasi   +3 more
doaj  

Effects of starvation on the carbohydrate metabolism in Harmonia axyridis (Pallas)

Biology Open, 2017
Trehalose plays an important role in energy storage, metabolism, and protection from extreme environmental conditions in insects. Trehalose is the main blood sugar in insects, and it can be rapidly used as an energy source in times of need.
Zuo-Kun Shi, Su Wang, Shi-Gui Wang, Lu Zhang, Yan-Xia Xu, Xiao-Jun Guo, Fan Zhang, Bin Tang   +7 more
doaj   +1 more source

Exploring plant tolerance to biotic and abiotic stresses [PDF]

, 2007
Plants are exposed to many stress factors, such as drought, high salinity or pathogens, which reduce the yield of the cultivated plants or affect the quality of the harvested products. Arabidopsis thaliana was used as a model plant to study the responses
Karim, Sazzad
core  

Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells [PDF]

Proceedings of the National Academy of Sciences, 2007
Trehalose is potentially a useful cryo- or anhydroprotectant molecule for cells and biomolecules such as proteins and nucleotides. A major obstacle to application is that cellular membranes are impermeable to trehalose. In this study, we isolated and characterized the functions of a facilitated trehalose transporter [trehalose transporter ...
Takahiro, Kikawada, Ayako, Saito, Yasushi, Kanamori, Yuichi, Nakahara, Ken-ichi, Iwata, Daisuke, Tanaka, Masahiko, Watanabe, Takashi, Okuda   +7 more
openaire   +2 more sources

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

A Novel Trehalose Synthase for the Production of Trehalose and Trehalulose

Microbiology Spectrum, 2021
Trehalose is a rare sugar of high importance in biological research, with its property to stabilize cell membrane and proteins and protect the organism from drought. It is instrumental in the cryopreservation of human cells, e.g., sperm and blood stem cells.
Neera Agarwal, Sudhir P. Singh
openaire   +3 more sources