Detection of Treponema pallidum tpp47 DNA in clinical samples of syphilis patients [PDF]
European Journal of Medical ResearchBackgrounds To investigate the relationship between the presence of Treponema pallidum DNA in saliva, serum, and cerebrospinal fluid (CSF) in patients with different stages of syphilis.
Yongjun Meng +5 more
doaj +2 more sources
Treponema pallidum protein Tp0136 promotes angiogenesis to facilitate the dissemination of Treponema pallidum [PDF]
Emerging Microbes and InfectionsThe incompletely eliminated Treponema pallidum (T. pallidum) during primary syphilis chancre infection can result in the progression of secondary, tertiary, or latent syphilis in individuals, suggesting that T. pallidum has successfully evaded the immune
Wei Li +8 more
doaj +2 more sources
Loop-mediated isothermal amplification assays for the rapid discrimination of Treponema pallidum lineages and subspecies [PDF]
Microbiology SpectrumMolecular surveillance aimed at identifying the subspecies and lineages of Treponema pallidum is important. Conventional molecular methods for genotyping are effective but are also time-consuming and costly.
Kazuo Imai +9 more
doaj +2 more sources
Advanced specificity and sensitivity studies relative to a research use only transcription-mediated amplification-based assay for Treponema pallidum RNA detection [PDF]
Journal of Clinical MicrobiologyPreliminary experimentation has suggested that a research-use-only real-time transcription-mediated amplification assay for Treponema pallidum (RUO T. pallidum TMA) yields instances of T.
Trinity Krueger +8 more
doaj +2 more sources
Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability [PDF]
Small ScienceThe Treponema pallidum membrane protein Tp0136 facilitates Treponema pallidum dissemination, and the permeability of vasculature is intricately linked to the density of the vascular endothelial barrier, which is strongly associated with the morphology of
Yu Lin +5 more
doaj +2 more sources
Sokoto Journal of Medical Laboratory ScienceSyphilis is a multi-stage, vertically (mother to child transmission) or sexually transmitted disease caused by Treponema pallidum. It is an obligate human pathogen renowned for its invasiveness and immune evasiveness.
Fadipe, D.O.1*, Omotuyi, I.O. 2 and Olajubu, F.A. 1
doaj +3 more sources
Imunopatogenesis Treponema pallidum dan Pemeriksaan Serologi [PDF]
Jurnal Kesehatan Andalas, 2014 AbstrakSifilis adalah penyakit menular seksual yang sangat infeksius, disebabkan oleh bakteri berbentuk spiral, Treponema pallidum subspesies pallidum.
Efrida ., Elvinawaty .
doaj +1 more source
Research progress in syphilis immunity
Pifu-xingbing zhenliaoxue zazhi, 2022 Syphilis is a sexually transmitted disease caused by treponema pallidum infection. It is mainly transmitted through mucous membrane or injured skin.
Ruihua ZHANG, Qianqiu WANG
doaj +1 more source
Characterization of Treponema pallidum Dissemination in C57BL/6 Mice
Frontiers in Immunology, 2021 The spirochetal pathogen Treponema pallidum causes 5 million new cases of venereal syphilis worldwide each year. One major obstacle to syphilis prevention and treatment is the lack of suitable experimental animal models to study its pathogenesis ...
Simin Lu +8 more
doaj +1 more source
Phylogeny and antibiotic resistance of Treponema pallidum subsp. pallidum [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 The species Treponema pallidum includes 4 subspecies. According to the bioinformatic analysis, the syphilis pathogen T. pallidum subsp. pallidum was probably separated from the causative agents of yaws, bejel, and pinta more than 800 years ago. Its entry
Nosov N.Yu. +4 more
doaj +1 more source