Results 51 to 60 of about 37,820 (203)

Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster [PDF]

open access: yes, 2016
The abrupt onslaught of the syphilis pandemic that started in the late fifteenth century established this devastating infectious disease as one of the most feared in human history.
A Centurion-Lara   +53 more
core   +2 more sources

Retrospective Analysis of Blood Donor Deferral Reasons and Optimization Suggestions for Deferral Policies

open access: yesiLABMED, EarlyView.
This retrospective study analyzes the deferral reasons for 148,282 blood donors during 2019–2023 (overall deferral rate: 12.37%), identifying primary deferral reasons (e.g., elevated ALT for temporary deferral at 51.33%, HBsAg positivity for permanent deferral at 4.12%).
Limei Feng   +5 more
wiley   +1 more source

Canadian Public Health Laboratory Network Laboratory Guidelines for the Use of Direct Tests to Detect Syphilis in Canada

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2015
Treponema pallidum subsp. pallidum and/or its nucleic acid can be detected by various methods such as microscopy, rabbit infectivity test or polymerase chain reaction (PCR) tests. The rabbit infectivity test for T.
Raymond SW Tsang   +4 more
doaj   +1 more source

Detection of Treponema pallidum subspecies pallidum for the diagnosis of congenital syphilis by nested polymerase chain reaction

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2018
Introduction. Syphilis is a disease produced by Treponema pallidum subspecies pallidum, which affects approximately 12 million people worldwide every year.
Gladys Pinilla   +4 more
doaj   +1 more source

The Treponema pallidum Outer Membrane [PDF]

open access: yes, 2017
The outer membrane (OM) of Treponema pallidum, the uncultivatable agent of venereal syphilis, has long been the subject of misconceptions and controversy. Decades ago, researchers postulated that T. pallidum's poor surface antigenicity is the basis for its ability to cause persistent infection, but they mistakenly attributed this enigmatic property to ...
Justin D, Radolf, Sanjiv, Kumar
openaire   +2 more sources

Mucopolysaccharidase of Treponema pallidum [PDF]

open access: yesInfection and Immunity, 1979
Treponema pallidum (Nichols strain) exhibited mucopolysaccharidase activity. Acidic mucopolysaccharides were broken down more rapidly by viable treponemes than by heat-inactivated treponemes or membrane filtrates of treponemal suspensions.
T J, Fitzgerald, R C, Johnson
openaire   +2 more sources

The composition of Ehrlich's salvarsan: Resolution of a century-old debate [PDF]

open access: yes, 2004
Ehrlich introduced in 1910 the compound 3-amino-4-hydroxyphenylarsenic(I) [Salvarsan, arsphenamine, Ehrlich 606,] as a remedy for syphilis, a disease caused by the spirochaete bacterium Treponema pallidum.
Breunig   +30 more
core   +2 more sources

THE TREPONEMA PALLIDUM [PDF]

open access: yesArchives of Internal Medicine, 1909
The discovery by Schaudinn and Hoffmann 1 in 1905 of a spirillum in various luetic lesions marked the beginning of a decided advance in our knowledge of the etiology of syphilis. The announcement of the discovery, while most conservative in its assertions, gave a fresh impetus to the study of the many phases presented in the parasitology and pathology ...
openaire   +1 more source

Reflectance confocal microscopy for the diagnosis of skin infections and infestations [PDF]

open access: yes, 2020
Reflectance confocal microscopy (RCM) is a noninvasive real-time imaging technique that has been widely used for the diagnosis of skin cancer. More recently, it has been reported as a useful tool for the diagnosis and management of several inflammatory ...
Arzberger, Edith   +6 more
core  

Diagnostics for Yaws Eradication: Insights From Direct Next-Generation Sequencing of Cutaneous Strains of Treponema pallidum. [PDF]

open access: yes, 2017
Background: Yaws-like chronic ulcers can be caused by Treponema pallidum subspecies pertenue, Haemophilus ducreyi, or other, still-undefined bacteria. To permit accurate evaluation of yaws elimination efforts, programmatic use of molecular diagnostics is
Butcher, Robert   +10 more
core   +2 more sources

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