Results 11 to 20 of about 935 (139)

Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania [PDF]

Emerging Infectious Diseases, 2018
We investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015–2017. We used a serologic treponemal test to detect antibodies against the bacterium.
Idrissa S. Chuma, Emmanuel K. Batamuzi, D. Anthony Collins, Robert D. Fyumagwa, Luisa K. Hallmaier-Wacker, Rudovick R. Kazwala, Julius D. Keyyu, Inyasi A. Lejora, Iddi F. Lipende, Simone Lüert, Filipa M.D. Paciência, Alexander Piel, Fiona A. Stewart, Dietmar Zinner, Christian Roos, Sascha Knauf   +15 more
doaj   +3 more sources

Rapid Serologic Test for Diagnosis of Yaws in Patients with Suspicious Skin Ulcers [PDF]

Emerging Infectious Diseases, 2023
The Chembio DPP (Dual Path Platform) Syphilis Screen & Confirm kit (https://chembio.com) is a rapid serologic test that can be used to diagnose yaws.
Clara Suñer, Lucy N. John, Wendy Houinei, Maria Ubals, Dan Ouchi, Andrea Alemany, Cristina Galván-Casas, Michael Marks, Oriol Mitjà, Martí Vall-Mayans, Camila G. Beiras   +10 more
doaj   +2 more sources

Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study [PDF]

The Lancet Global Health, 2017
Summary: Background: Treatment of latent yaws is a crucial component of the WHO yaws eradication strategy to prevent relapse and the resulting transmission to uninfected children.
Oriol Mitjà, DrMD, Camila González-Beiras, BSc, Charmie Godornes, BSc, Reman Kolmau, BSc, Wendy Houinei, HEO, Haina Abel, BSc, August Kapa, BSc, Raymond Paru, BSc, Sibauk V Bieb, MaHM, James Wangi, MPH, Sergi Sanz, MSc, Kingsley Asiedu, MPH, Sheila A Lukehart, ProfPhD, Quique Bassat, ProfMD   +13 more
doaj   +2 more sources

Mapping the distribution of yaws and Haemophilus ducreyi in the western north region of Ghana [PDF]

BMC Infectious Diseases
Background Treponema pallidum subspecies pertenue and Haemophilus ducreyi cause skin ulcers in impoverished communities. Historical serologic records from Ghana focus on T. pallidum, omitting potential H. ducreyi cases. The objective of this study was to
Shirley Victoria Simpson, Hiroaki Arima, Eric Behene, Sabin S. Nundu, John Hammond, Rita Atta-Owusu, Paul Noah-Quarm, Nana Konama Kotey, Kingsley Asiedu, Kennedy Kwasi Addo, Rie Roselyne Yotsu, Taro Yamamoto   +11 more
doaj   +2 more sources

Genome analysis of Treponema pallidum subsp. pallidum and subsp. pertenue strains: most of the genetic differences are localized in six regions.

PLoS ONE, 2010
The genomes of eight treponemes including T. p. pallidum strains (Nichols, SS14, DAL-1 and Mexico A), T. p. pertenue strains (Samoa D, CDC-2 and Gauthier), and the Fribourg-Blanc isolate, were amplified in 133 overlapping amplicons, and the restriction ...
Lenka Mikalová, Michal Strouhal, Darina Čejková, Marie Zobaníková, Petra Pospíšilová, Steven J Norris, Erica Sodergren, George M Weinstock, David Šmajs   +8 more
doaj   +4 more sources

Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively.

PLoS Neglected Tropical Diseases, 2017
BackgroundTreponema pallidum subsp. endemicum (TEN) is the causative agent of endemic syphilis (bejel). An unusual human TEN 11q/j isolate was obtained from a syphilis-like primary genital lesion from a patient that returned to France from Pakistan ...
Lenka Mikalová, Michal Strouhal, Jan Oppelt, Philippe Alain Grange, Michel Janier, Nadjet Benhaddou, Nicolas Dupin, David Šmajs   +7 more
doaj   +4 more sources

Survey of Treponemal Infections in Free-Ranging and Captive Macaques, 1999–2012 [PDF]

Emerging Infectious Diseases, 2017
Survey results showed treponemal infection among pet macaques in Southeast Asia, a region with a high prevalence of human yaws. This finding, along with studies showing treponemal infection in nonhuman primates in Africa, should encourage a One Health ...
Amy R. Klegarth, Chigozie A. Ezeonwu, Aida Rompis, Benjamin P.Y.-H. Lee, Nantiya Aggimarangsee, Mukesh Chalise, John Cortes, M. Feeroz, Barbara J. Molini, Bess C. Godornes, Michael Marks, Michael Schillaci, Gregory Engel, Sascha Knauf, Sheila A. Lukehart, Lisa Jones-Engel   +15 more
doaj   +3 more sources

The etiology of exudative cutaneous ulcers in a yaws-endemic community prior to receipt of antimicrobials is similar to that found in communities after mass treatment with azithromycin [PDF]

mSphere
Mass drug administration (MDA) of azithromycin (AZ) and case finding and treatment of children with cutaneous ulcers (CUs) have been trialed as strategies to eliminate yaws. Metagenomic sequencing of CU swabs obtained from children 3 to 4 years after the
Julie A. Brothwell, Evelyn Toh, Yue Xing, Qunfeng Dong, Linda H. Xu, Lorenzo Giacani, Camila G. Beiras, Oriol Mitjà, Xiang Gao, Stanley M. Spinola   +9 more
doaj   +2 more sources

Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. [PDF]

PLoS Neglected Tropical Diseases, 2016
IntroductionBoth yaws and trachoma are endemic in the Pacific. Mass treatment with azithromycin is the mainstay of the WHO strategy for both the eradication of yaws and the elimination of trachoma as a public health problem, but the dose recommended for ...
Michael Marks, Oliver Sokana, Eli Nachamkin, Elliot Puiahi, Georgina Kilua, Allan Pillay, Christian Bottomley, Anthony W Solomon, David C Mabey   +8 more
doaj   +4 more sources

Coinfection of a yaws patient with two closely related Treponema pallidum subsp. pertenue strains : A rare event with potential evolutionary implications [PDF]

Acta Tropica
The etiological agent of yaws is the spirochete Treponema pallidum (TP) subsp. pertenue (TPE) and infects the children of Papua New Guinea, causing ulcerative skin lesions that impairs normal growth and development.
González-Beiras, Camila, John, L.N., Medappa, M., Mitjà, Oriol, Pospíšilová, P., Universitat Autònoma de Barcelona, Šmajs, D.   +6 more
core   +6 more sources