Results 31 to 40 of about 935 (139)

Yaws in the Philippines: A clinico-seroprevalence study of selected communities in Mindanao.

PLoS Neglected Tropical Diseases, 2022
BackgroundYaws is a chronic, highly contagious skin and bone infection affecting children living in impoverished, remote communities. It is caused by Treponema pallidum subsp. pertenue.
Belen Lardizabal Dofitas, Sherjan P Kalim, Camille B Toledo, Jan Hendrik Richardus   +3 more
doaj   +2 more sources

Epidemic of venereal treponematosis in wild monkeys: a paradigm for syphilis origin

New Microbes and New Infections, 2020
Treponema pallidum infections have been primarily known as slightly contagious mucocutaneous infections called yaws (tropical Africa and America) and bejel (subtropical North Africa). T.
O. Mediannikov, F. Fenollar, B. Davoust, N. Amanzougaghene, H. Lepidi, J.-P. Arzouni, G. Diatta, C. Sokhna, J. Delerce, A. Levasseur, D. Raoult   +10 more
doaj   +1 more source

No evidence for yaws infection in a small‐scale cross‐sectional serosurvey in Ghanaian monkeys

Veterinary Medicine and Science, 2023
Background Treponema pallidum (TP) is a spirochaete bacterium with subspecies that in humans cause syphilis (subsp. pallidum), bejel (subsp. endemicum) and yaws (subsp. pertenue; TPE).
Eugene Adade, Christian Roos, Idrissa Shomari Chuma, Augustina Angelina Sylverken, Sascha Knauf   +4 more
doaj   +1 more source

Treponema pallidum infection in the wild baboons of East Africa: distribution and genetic characterization of the strains responsible. [PDF]

PLoS ONE, 2012
It has been known for decades that wild baboons are naturally infected with Treponema pallidum, the bacterium that causes the diseases syphilis (subsp. pallidum), yaws (subsp. pertenue), and bejel (subsp. endemicum) in humans.
Kristin N Harper, Robert D Fyumagwa, Richard Hoare, Philemon N Wambura, Dorian H Coppenhaver, Robert M Sapolsky, Susan C Alberts, Jenny Tung, Jeffrey Rogers, Morris Kilewo, Emmanuel K Batamuzi, Fabian H Leendertz, George J Armelagos, Sascha Knauf   +13 more
doaj   +1 more source

Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum.

PLoS Neglected Tropical Diseases, 2021
BackgroundAn effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis.
Austin M Haynes, Mark Fernandez, Emily Romeis, Oriol Mitjà, Kelika A Konda, Silver K Vargas, Maria Eguiluz, Carlos F Caceres, Jeffrey D Klausner, Lorenzo Giacani   +9 more
doaj   +1 more source

African nonhuman primates are infected with the yaws bacteriumTreponema pallidumsubsp.pertenue [PDF]

, 2017
AbstractTreponema pallidumsubsp.pertenue(TPE) is the causative agent of yaws. The disease was subject to global eradication efforts in the mid 20thcentury but reemerged in West Africa, Southern Asia, and the Pacific region. Despite its importance for eradication, detailed data on possible nonhuman disease reservoirs are missing.
Knauf, Sascha, Gogarten, Jan F., Schuenemann, Verena J., De Nys, Hélène M., Düx, Ariane, Strouhal, Michal, Mikalová, Lenka, Bos, Kirsten I., Armstrong, Roy, Batamuzi, Emmanuel K., Chuma, Idrissa S., Davoust, Bernard, Diatta, Georges, Fyumagwa, Robert D., Kazwala, Reuben R., Keyyu, Julius D., Lejora, Inyasi A. V., Levasseur, Anthony, Liu, Hsi, Mayhew, Michael A., Mediannikov, Oleg, Raoult, Didier, Wittig, Roman M., Roos, Christian, Leendertz, Fabian H., Šmajs, David, Nieselt, Kay, Krause, Johannes, Calvignac-Spencer, Sébastien   +28 more
openaire   +2 more sources

Immune T cells sorted by flow cytometry confer protection against infection with Treponema pallidum subsp. pertenue in hamsters [PDF]

Infection and Immunity, 1990
The role of cell-mediated immunity against infection with Treponema pallidum subsp. pertenue in humans or experimental animals is unclear. Hamsters injected subcutaneously in the hind paws with 4 x 10(6) unfractionated lymph node cells or enriched lymph node T cells (immunoglobulin negative, Ia negative) from T. pallidum subsp. pertenue-immune hamsters
H, Liu, B M, Steiner, J D, Alder, D K, Baertschy, R F, Schell   +4 more
openaire   +2 more sources

Diagnostics for Yaws Eradication: Insights From Direct Next-Generation Sequencing of Cutaneous Strains of Treponema pallidum. [PDF]

, 2017
Background: Yaws-like chronic ulcers can be caused by Treponema pallidum subspecies pertenue, Haemophilus ducreyi, or other, still-undefined bacteria. To permit accurate evaluation of yaws elimination efforts, programmatic use of molecular diagnostics is
Butcher, Robert, Fookes, Maria, Ghinai, Rosanna, Lukehart, Sheila A, Mabey, David CW, Marks, Michael, Sarkodie, Yaw-Adu, Sokana, Oliver, Solomon, Anthony W, Thomson, Nicholas, Wagner, Josef   +10 more
core   +2 more sources

Role of L3T4+ and 38+ T-cell subsets in resistance against infection with Treponema pallidum subsp. pertenue in hamsters [PDF]

Infection and Immunity, 1991
The protective immunity conferred by T-cell subsets against infection with Treponema pallidum subsp. pertenue was studied. We demonstrated that hamster T cells can be separated into two subsets by monoclonal antibody (MAb) GK 1.5 (anti-L3T4) and MAb 38.
H, Liu, J D, Alder, B M, Steiner, J, Stein-Streilein, L, Lim, R F, Schell   +5 more
openaire   +2 more sources

Female post-copulatory behavior in a group of olive baboons (Papio anubis) infected by Treponema pallidum.

PLoS ONE, 2022
Pathogens exert a profound and pervasive cost on various aspects of primate sociality and reproduction. In olive baboons (Papio anubis) at Lake Manyara National Park, Tanzania, genital skin ulcers, caused by the bacterium Treponema pallidum subsp ...
Filipa M D Paciência, Idrissa S Chuma, Iddi F Lipende, Sascha Knauf, Dietmar Zinner   +4 more
doaj   +1 more source