Results 131 to 140 of about 13,020 (271)
Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice
American Journal of Hematology, Volume 101, Issue 9, Page 2105-2122, September 2026.ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim +13 more
wiley +1 more source
Equine Veterinary Education, Volume 38, Issue 9, Page e622-e630, September 2026.Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken +5 more
wiley +1 more source
Reviews in Aquaculture, Volume 18, Issue 4, September 2026.Syndromic convergence (SyCo) reframes aquaculture disease as the synergistic product of climate‐driven stressors, pathobiome communities, and host immune compromise, not single pathogens. A five‐criterion scoring matrix, composite early warning index, and three‐layer intervention framework together operationalize this shift toward predictive ...
Ilhan Altinok
wiley +1 more source
Localization sequences for logarithmic topological cyclic homology
Journal of Topology, Volume 19, Issue 3, September 2026.Abstract We introduce the notion of an Ek$\mathbb {E}_k$‐ring with prelogarithmic structure, define logarithmic topological Hochschild homology and logarithmic topological cyclic homology in this context, and establish localization sequences for these theories. Our approach is based on Thom R$R$‐algebras.
John Rognes +2 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, Volume 30, Issue 4, Page 585-593, August 2026.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease. Despite advances in targeted therapies, significant interindividual variability in treatment response and a lack of precise predictive tools limit the achievement of treat‐to‐target goals.
Shijie Meng +8 more
wiley +1 more source
G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation
Advanced Science, Volume 13, Issue 45, 13 August 2026.G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang +5 more
wiley +1 more source
Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies
Advanced Science, Volume 13, Issue 47, 24 August 2026.This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang +7 more
wiley +1 more source
Advanced Intelligent Systems, Volume 8, Issue 8, August 2026.A physics‐guided deep learning framework, ParamNet, is introduced for the intelligent self‐inversion of vacuum optical tweezers. By fuzing dual‐branch time–frequency features with physical dynamical constraints, it achieves high‐accuracy calibration of trap parameters from short‐window, low‐frequency trajectories, outperforming traditional methods ...
Qi Zheng +4 more
wiley +1 more source