Unraveling the causal link between lipidomes and unstable angina pectoris: A Mendelian randomization analysis. [PDF]
Pan W, Yu M, Chen Z.
europepmc +1 more source
HFD withdrawal results in early restoration of systemic glucose tolerance and PVAT lipid unsaturation that is temporarily dissociated from the reversal of endothelial dysfunction in aorta that may be linked to altered PVAT function featured by impaired guanylate cyclase signaling pathway.
Krzysztof Czamara +11 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Author Correction: Regulating triacylglycerol cycling for high-efficiency production of polyunsaturated fatty acids and derivatives. [PDF]
Du F +8 more
europepmc +1 more source
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
The Mycobacterium tuberculosis MmpL11 cell wall lipid transporter is important for biofilm formation, intracellular growth, and nonreplicating persistence [PDF]
Arnett, Eusondia +9 more
core +2 more sources
Specific organelle targeting as a key step in epidermal lipid synthesis. [PDF]
Schratter M, Radner FPW.
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Comparative Transcriptomics Reveals the Molecular Basis for Inducer-Dependent Efficiency in Gastrodin Propionylation by <i>Aspergillus oryzae</i> Whole-Cell Biocatalyst. [PDF]
Wu D, Ma M, Liu X, Li X, Zhao G.
europepmc +1 more source

