Results 201 to 210 of about 143,826 (243)
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Conversion of a Mono‐ and Diacylglycerol Lipase into a Triacylglycerol Lipase by Protein Engineering
ChemBioChem, 2015AbstractDespite the fact that most lipases are believed to be active against triacylglycerides, there is a small group of lipases that are active only on mono‐ and diacylglycerides. The reason for this difference in substrate scope is not clear. We tried to identify the reasons for this in the lipase from Malassezia globosa. By protein engineering, and
Dongming Lan +5 more
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Identification of a triacylglycerol lipase in the diatom Phaeodactylum tricornutum.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2016Diatoms accumulate triacylglycerols (TAGs) as storage lipids, but the knowledge about the molecular mechanisms of lipid metabolism is still sparse. Starting from a partial sequence for a putative TAG-lipase of the diatom Phaeodactylum tricornutum retrieved from the data bases, we have identified the full length coding sequence, tgl1.
Frederik Barka +5 more
semanticscholar +3 more sources
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012
The hallmark of obesity and one of the key contributing factors to insulin resistance, type 2 diabetes and cardiovascular disease is excess triacylglycerol (TG) storage. In hepatocytes, excessive accumulation of TG is the common denominator of a wide range of clinicopathological entities known as nonalcoholic fatty liver disease, which can eventually ...
Richard Lehner, Ariel D. Quiroga
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The hallmark of obesity and one of the key contributing factors to insulin resistance, type 2 diabetes and cardiovascular disease is excess triacylglycerol (TG) storage. In hepatocytes, excessive accumulation of TG is the common denominator of a wide range of clinicopathological entities known as nonalcoholic fatty liver disease, which can eventually ...
Richard Lehner, Ariel D. Quiroga
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Triacylglycerol lipase in bovine erythrocytes
International Journal of Biochemistry, 1985Acid lipase activity was found in the bovine erythrocyte ghosts, but little neutral or alkaline lipase activity was observed in the erythrocytes. The membrane-bound lipase showed a remarkable activity in the ghosts only after hemolysis. The membrane-bound lipase showed its maximum activity at pH 4.5, 38 degrees C, and it was stable below 40 degrees C ...
Koga Katsuya +2 more
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Triacylglycerol lipases of the yeast
Frontiers in Biology, 2011All eukaryotes including the yeast contain a lipid storage compartment which is named lipid particle, lipid droplet or oil body. Lipids accumulating in this subcellular fraction serve as a depot of energy and building blocks for membrane lipid synthesis. In the yeast, the major storage lipids are triacylglycerols (TGs) and steryl esters (SEs).
Karlheinz Grillitsch, Günther Daum
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Triacylglycerol Lipases in Adrenals and Testes of Rats
The Journal of Biochemistry, 1982Triacylglycerol lipase activities in adrenals and testes of rats were measured and the properties of the enzymes were characterized. The enzymes were extracted from acetone-ether dried powder of the tissues and the crude extracts were applied to a heparin-Sepharose affinity column.
Nakaaki Ohsawa +3 more
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Triacylglycerol metabolism and triacylglycerol lipase activities of cultured human skin fibroblasts
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1980The relative contribution of lipoproteins and free fatty acid to the cellular triacylglycerol content of cultured human fibroblasts was tested. Fibroblasts accumulated triacylglycerol in proportion to the molar ratio of free fatty acid (oleic acid) to albumin in the medium.
Edwin L. Bierman +2 more
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Regioselective analysis of triacylglycerols by lipase hydrolysis
Journal of the American Oil Chemists' Society, 1995AbstractA modified procedure for the regiospecific analysis of triacylglycerols (TAG) with a 1,3‐specific lipase is described. After partial lipase hydrolysis of the triacylglycerol, the released free fatty acids (FFA) and 1,2(2,3)‐diacylglycerols (DAG) were isolated by thin‐layer chromatography (TLC) and converted to fatty acid methyl esters (FAME ...
Thomas A. Foglia +2 more
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Effect of cholera toxin on triacylglycerol lipase activity and triacylglycerol content of rat heart [PDF]
Canadian Journal of Physiology and Pharmacology, 1987 This study was performed to reexamine the effect of cholera toxin on total and intracellular alkaline lipoprotein lipase (LPL) activity in rat heart. In addition, the relationship between intracellular triacylglycerol (TG)lipase activity and TG content of cardiac tissue was determined in cholera toxin treated rats. One intravenous injection of cholera
David A. Arnall +3 more
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Triacylglycerol lipase activity in the rabbit renal medulla
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1987Although the renal medulla is rich in triacylglycerols, the lipolysis of these intracellular triacylglycerols by a renomedullary triacylglycerol lipase has not been directly demonstrated. The present study demonstrates triacylglycerol lipase activity localized in the particulate subcellular fractions of rabbit renal medullae.
Theodore E. Liston, Alberto Nasjletti
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