Results 131 to 140 of about 11,188,116 (297)

Prevalence and risk factors of falls among the older adults in Gulf Cooperation Council countries: insights from a systematic review

BMC Public Health
Background The average life expectancy in the Gulf Cooperation Council (GCC) countries has increased over the past few decades, contributing to an increase in the older adult population in the GCC countries.
Abdullah Alawlah, Ashraf A’aqoulah, Reem Alamr, Ashraf El-Metwally   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Summons of freeholders to Phillip's trial

This document is a legal writ issued by Samuel Dickinson and John Vining, two Justices of the Peace for Kent County. It outlines the commission assigned to Philip Brady (Bradey), a constable, to summon freeholders Benjamin Chew, Nathaniel Luff, Stephen ...
Kent County Court for the Trial of Negro Slaves
core   +1 more source

Clinical data analysis research on tuberculosis based on machine learning

Frontiers in Medicine
BackgroundTuberculosis (TB) remains a global health challenge, with heterogeneous treatment outcomes despite standardized protocols. Traditional statistical models struggle with high-dimensional clinical data, necessitating advanced machine learning (ML)
Rongrong Kang, Huanqing Liu, Qian Lei, Tingting Li   +3 more
doaj   +1 more source

Stimulating demand for AIDS prevention : lessons from the RESPECT trial [PDF]

HIV-prevention strategies have yielded only limited success so far in slowing down the AIDS epidemic. This paper examines novel intervention strategies that use incentives to discourage risky sexual behaviors.
Dow, William H., Medlin, Carol, de Walque, Damien, Nathan, Rose   +3 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Trial analytics--a tool for clinical trial management.

Acta poloniae pharmaceutica, 2012
Prolonged timelines and large expenses associated with clinical trials have prompted a new focus on improving the operational efficiency of clinical trials by use of Clinical Trial Management Systems (CTMS) in order to improve managerial control in trial conduct.
Anindya, Bose, Suman, Das
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

An innovative protocol for the artificial speech-directed, contactless administration of laboratory-based comprehensive cognitive assessments: PAAD-2 trial management during the COVID-19 pandemic. [PDF]

Contemp Clin Trials, 2021
Park KS, Etnier JL.
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source