Results 111 to 120 of about 6,757,255 (356)

Clinical Trials Unit Newsletter - Issue 01 [PDF]

open access: yes
What\u27s inside this issue: AKU receives JCIA reaccreditation - Clinical Trials Unit rejoice Director’s Message Informative Snippets AKU Site Surpasses Target Sample Size in the D-LIVR Global Trial Clinical Trials Unit celebrates World Pharmacists Day ...
Clinical Trials Unit (CTU),
core   +1 more source

In medicine today – Cancer and the prorogation of clinical reality in favour of probabilistic outcomes

open access: yesForum of Clinical Oncology
How essential is the randomised trial in cancer therapeutics? Is it conceivable that prospective randomised clinical trials in cancer medicine could, one day, safely be abandoned in favour of Phase II studies supplemented with real-world data from cancer
Retsas Spyros
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research Report 2012 [PDF]

open access: yes, 2013
The NHMRC Clinical Trials Centre at the University of Sydney runs large multicentre investigator-initiated clinical trials, undertakes research with national and international trial groups, and contributes expertise to trials run by others.
NHMRC Clinical Trials Centre
core  

La azarosa vida y la cruel muerte del morisco sodomita Gregorio Xeus (1583)

open access: yesMélanges de la Casa de Velázquez
Gregorio Xeus was a Valencian Morisco (16th century), denounced before the Inquisition, accused of having committed the crime of sodomy. The trial preserved in the Archivo Histórico Nacional in Madrid provides us with key information about his life and ...
Vicent Josep Escartí
doaj   +1 more source

The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials

open access: yesBritish medical journal, 2011
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated.
Julian P. T. Higgins   +9 more
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Research Report 2006–2007 [PDF]

open access: yes, 2008
The National Health and Medical Research Council Clinical Trials Centre conducts its own clinical trials, provides expertise and infrastructure for trials run by other groups, and undertakes research aiming to improve both the conduct of trials and the ...
NHMRC Clinical Trials Centre
core  

Outcomes in Trials for Management of Caries Lesions (OuTMaC):protocol [PDF]

open access: yes, 2015
BackgroundClinical trials on caries lesion management use an abundance of outcomes, hampering comparison or combination of different study results and their efficient translation into clinical practice.
Lamont, T.   +8 more
core   +2 more sources

PD-1/PD-L1 inhibitors plus chemotherapy as first-line therapy for advanced or metastatic endometrial cancer: a systematic review and meta-analysis of randomized controlled trials

open access: yesFrontiers in Immunology
ObjectiveTo evaluate the efficacy and safety of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors combined with chemotherapy as first-line treatment for advanced or metastatic endometrial cancer.MethodsA systematic literature search ...
Zhilong Huang   +5 more
doaj   +1 more source

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