Results 1 to 10 of about 157,767 (395)

Triazole analogues as potential pharmacological agents: a brief review

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background A large number of studies have recently reported that, because of their significant biological and pharmacological properties, heterocyclic compounds and their derivatives have attracted a strong interest in medicinal chemistry.
Sachin Kumar   +2 more
doaj   +2 more sources

Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

open access: yesmBio, 2019
Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state credited with over 200,000 life-threatening infections each year.
Jeffrey M. Rybak   +6 more
doaj   +2 more sources

1,2,4-Triazoles. VII. Methylation of 1,2,4-triazoles.

open access: bronzeChemical and Pharmaceutical Bulletin, 1976
AbstractMethylierung von 1,2,4‐Triazol und dessen symmetrisch 3,5‐disubst.
Masayuki Uda   +3 more
openalex   +5 more sources

Recent developments on triazole nucleus in anticonvulsant compounds: a review

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
Epilepsy is one of the common diseases seriously threatening life and health of human. More than 50 million people are suffering from this condition and anticonvulsant agents are the main treatment.
Ming-Xia Song, Xian-Qing Deng
doaj   +2 more sources

Synthesis methods of 1,2,3-/1,2,4-triazoles: A review

open access: yesFrontiers in Chemistry, 2022
Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers 1,2,3-triazole and 1,2,4-triazole. Compounds containing a triazole are one of the significant heterocycles that exhibit broad biological activities, such as ...
Jinlian Dai   +3 more
doaj   +1 more source

Utility of triazole antifungal therapeutic drug monitoring: Insights from the Society of Infectious Diseases Pharmacists

open access: yesPharmacotherapy, 2023
Triazole antifungals (i.e., fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) are commonly used in clinical practice to prevent or treat invasive fungal infections.
E. McCreary   +9 more
semanticscholar   +1 more source

Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review

open access: yesAntibiotics, 2023
Bacterial infections have attracted the attention of researchers in recent decades, especially due to the special problems they have faced, such as their increasing diversity and resistance to antibiotic treatment.
M. Marinescu
semanticscholar   +1 more source

Fluorescent Analogues of FRH Peptide: Cu(II) Binding and Interactions with ds-DNA/RNA

open access: yesChemosensors, 2022
Four novel peptidoids, derived from the Phe-Arg-His (FRH) peptide motif, were prepared by replacing the histidine heterocycle with triazole and consequent triazole-fluorophore (coumarin) extension and also replacing arginine with less voluminous lysine ...
Marta Košćak   +3 more
doaj   +1 more source

Genome-Wide Association Analysis for Triazole Resistance in Aspergillus fumigatus

open access: yesPathogens, 2021
Aspergillus fumigatus is a ubiquitous fungus and the main agent of aspergillosis, a common fungal infection in the immunocompromised population. Triazoles such as itraconazole and voriconazole are the common first-line drugs for treating aspergillosis ...
Yuying Fan   +4 more
doaj   +1 more source

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