Results 91 to 100 of about 80,033 (290)
Crystal structure of 2-(4-fluoro-3-methylphenyl)-5-{[(naphthalen-1-yl)oxy]methyl}-1,3,4-oxadiazole
The title compound, C20H15FN2O2, adopts an almost planar conformation. The oxadiazole ring makes dihedral angles of 13.90 (1) and 7.93 (1)° with the naphthalene ring system and benzene ring, respectively, while the naphthalene ring system and benzene ...
Muniyappan Govindhan +3 more
doaj +1 more source
Pulmonary Verruconis Infection in an Immunocompetent Patient: A Case Report and Literature Review
Verruconis species are thermophilic, darkly pigmented fungi commonly found in hot environments. Despite their environmental ubiquity, fewer than fifty human infections have been reported, with V. gallopava responsible for most cases.
Lulu Xu, Lili Tao
doaj +1 more source
Cyclization of acyclic <em>C</em>-glycoside derivatives <strong>1a,b</strong> to <strong>2a,b</strong> as the major isomers, and <strong>4a,b</strong> as the minor isomers were carried out.
Nagwa Said Abd El-Dayem +3 more
doaj +1 more source
Mono-, bis-, and tris-1,2,3-triazole ligands are used for the stabilization of gold nanoparticles (AuNPs), and the catalytic activities of these AuNPs in 4-nitrophenol reduction by NaBH4 in water are compared as well as with polyethylene glycol 2000 (PEG)
Sergio Moya (1353486) +7 more
core +1 more source
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani +7 more
wiley +2 more sources
A series of 28 compounds, 3-nitro-1H-1,2,4-triazole, were synthesized by click-chemistry with diverse substitution patterns using medicinal chemistry approaches, such as bioisosterism, Craig-plot, and the Topliss set with excellent yields.
Carla C. P. Arruda (15367833) +20 more
core +2 more sources
Review on substituted 1, 2, 4-triazoles as potent antifungal and antibacterial agents
For the past two decades, modification of 1, 2, 4 triazole nucleus have made a tremendous significance in medicinal chemistry. 1, 2, 4 triazoles and their derivatives are found to have wide variety of pharmacological uses.
Subhas Sahoo +2 more
doaj
1-[(1-Benzyl-1H-1,2,3-triazol-4-yl)methyl]-1H-1,3-benzodiazole
The title molecule, C17H15N5, adopts a Z-shaped conformation, with the benzyl and benzodiazole substituents disposed on opposite sides of the plane of the triazole ring.
Azzeddine Sahbi +5 more
doaj +1 more source
New Quinoline-Based Heterocycles as Anticancer Agents Targeting Bcl-2
The Bcl-2 protein has been studied as an anticancer drug target in recent years, due to its gatekeeper role in resisting programmed cancer cell death (apoptosis), and the design of BH3 domain mimetics has led to the clinical approval of Venetoclax (ABT ...
Rania Hamdy +4 more
doaj +1 more source
Polymorphism of four biologically active 3-(4,5-diaryl-4H-1,2,4-triazole-3-yl)propenoic acid derivatives has been investigated. Traditional solution-based solid-state forms screening revealed three anhydrous forms of 3-[4-phenyl-5-(2-pyridyl)-4H-1,2,4 ...
Anna E. Koziol (3053643) +4 more
core +1 more source

