Results 61 to 70 of about 30,894 (155)

1,2,4-Triazole-3,5-diylidene:  A Building Block for Organometallic Polymer Synthesis

, 2016
1,2,4-Triazole-3,5-diylidene:  A Building Block for Organometallic Polymer ...
Olivier Guerret (2728345), Stéphane Solé (2990865), Georges Trinquier (1886878), Heinz Gornitzka (1385718), Markus Teichert (2975172), Guy Bertrand (1453126)   +5 more
core   +1 more source

Advances in the synthesis of 1,2,3-triazole based energetic compounds: A review

Defence Technology
1,2,3-Triazole-based energetic compounds have attracted widespread attention in the field of energetic materials due to their high heats of formation, high density, good stability, and environmental friendliness.
Bibo Li, Zhongchao Li, Xinghui Liu, Jianlong Wang, Yunlu Li, Shangbiao Feng, Ping Yin   +6 more
doaj   +1 more source

The synthesis of [1,2,3]-triazole-based bent core liquid crystals via microwave-mediated ‘Click Reaction’ and their mesomorphic behaviour

, 2019
A series of [1,2,3]-triazole-based liquid crystal compounds were synthesised via a fast and efficient microwave-mediated ‘Click Reaction’ and their phase behaviour is presented.
Samuel Sprunt (2529220), Kunlun Wang (2794564), Robert J. Twieg (567348)   +2 more
core   +1 more source

Crystal structure and Hirshfeld surface analysis of the fungicide metconazole

Acta Crystallographica Section E: Crystallographic Communications
Metconazole is a systemic triazole fungicide that inhibits the ergosterol biosynthesis pathway. It is widely used in agriculture to control fungal infections, including rusts, fusarium and septoria diseases. The molecular structure is a three-ring system,
Thaluru M. Mohan Kumar, Chaluvarangaiah Sowbhagya, Hemmige S. Yathirajan, Sean Parkin   +3 more
doaj   +1 more source

6-tert-Butyl-4-[(4-hydroxymethyl-2H-1,2,3-triazol-2-yl)methyl]-2H-chromen-2-one

IUCrData, 2016
In the title compound, C17H19N3O3, the triazole ring and the chromene ring system [maximum deviation = 0.018 (2) Å for the O atom] bridged via a methylene C atom, are inclined to one another by 73.2 (1)°.
Nasseem El-Khatatneh, Chandra, D. Shamala, K. Shivashankar, M. Mahendra   +4 more
doaj   +1 more source

Triazole-based radiopeptidomimetics : novel neurotensin (8-13) analogues with increased metabolic stability [PDF]

, 2015
Neurotensin (NT) is a regulatory peptide with a nanomolar affinity towards NT receptors, which are overexpressed by different types clinically relevant tumours (e.g. Ewing’ sarcoma, breast, colon and exocrine pancreatic cancer).
Mascarin, Alba
core   +1 more source

Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity

Molecules, 2017
Artemisinin and synthetic derivatives of dihydroartemisinin are known to possess various biological activities. Post-functionalization of dihydroartemisinin with triazole heterocycles has been proven to lead to enhanced therapeutic potential.
Sampad Jana, Shabina Iram, Joice Thomas, Muhammad Qasim Hayat, Christophe Pannecouque, Wim Dehaen   +5 more
doaj   +1 more source

1,2,4-Oxadiazoles from cycloreversions of oxadiazabicyclo[3.2.0]heptenes: 1-azetines as thiocyanate equivalents [PDF]

, 2013
1,3-Dipolar cycloaddition of nitrile oxides to 4-aryl-2-alkylthio-1-azetines gave a series of oxadiazabicyclo[3.2.0]heptenes as single diastereoisomers. Heating these cycloadducts in toluene resulted in an overall [2+2]-cycloreversion to give 5-alkylthio-
Khan, Musharraf, Khan, Musharraf N., O'Gorman, Paul A., Pitard, Arnaud, Hemming, Karl, O'Gorman, P.A.   +5 more
core   +1 more source

Synthesis of 1H-1,2,3-triazole-4-carbonitriles as building blocks for promising 2-(triazol-4-yl)-thieno[2,3-d]pyrimidine drug candidates

, 2021
A new synthetic route leading to functionalized 1H-1,2,3-triazole-4-carbonitriles has been developed. A set of 1-aryl-5-methyl-1H-1,2,3-triazole-4-carbonitriles was obtained in high yields from readily available starting 1H-1,2,3-triazole-4-carboxylic ...
Taras V. Sekh (11341646), Nazariy T. Pokhodylo (526405), Mykola D. Obushak (11341652), Olga Y. Shyyka (11341649)   +3 more
core   +1 more source

Design and Synthesis of Novel 3‑Nitro‑1H‑1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis

A series of 28 compounds, 3-nitro-1H-1,2,4-triazole, were synthesized by click-chemistry with diverse substitution patterns using medicinal chemistry approaches, such as bioisosterism, Craig-plot, and the Topliss set with excellent yields.
Carla C. P. Arruda (15367833), Gisele B. Portapilla (17895571), Cristiane Y. K. Shiguemoto (17895574), Fernanda Silva (4425223), Eliane M. Piranda (15367827), Diego B. Carvalho (15367806), Sergio de Albuquerque (14641304), M. Cristina Nonato (17895583), Kelly M. P. Oliveira (15367818), Norberto P. Lopes (420366), Jaqueline C. Z. Batista (17895568), Denise B. Silva (15367830), Bruno I. Pelizaro (17895565), Edgar J. Paredes-Gamero (491141), Lucas R. Pessatto (15367824), Amarith R. das Neves (17066794), Nadla S. Cassemiro (15367821), Iara A. Cardoso (17895577), Pedro H. Luccas (17895580), Fernanda Galvão (17895586), Adriano C. M. Baroni (2985447)   +20 more
core   +2 more sources