Results 321 to 330 of about 126,240 (387)

New Methods for Synthesis of 1,2,3-Triazoles: A Review

Polycyclic aromatic compounds (Print), 2021
1,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms.
Bakthavatchala Reddy Nemallapudi, Dinneswara Reddy Guda, Nagarjuna Ummadi, B. Avula, G. Zyryanov, C. S. Reddy, S. Gundala   +6 more
semanticscholar   +1 more source

Recent progress on 1H-1,2,3-triazoles as potential antifungal agents.

Current Topics in Medicinal Chemistry, 2021
To overcome ever increasing cases of antifungal resistance and circumventing side effects and drug interactions related with currently available drugs has impelled the need to expedite the process of drug discovery and development of novel antifungals. 1,
Nisha Poonia, A. Kumar, Vijay Kumar, M. Yadav, Kashmiri Lal   +4 more
semanticscholar   +1 more source

Developments in the Application of 1,2,3-Triazoles in Cancer Treatment.

Recent Patents on Anti-Cancer Drug Discovery, 2020
BACKGROUND The impact of cancer on modern society cannot be emphasized enough in terms of both economic and human costs. Cancer treatments are known, unfortunately, for their side effects - frequently numerous and severe. Drug resistance is another issue
Katerina I Slavova, L. Todorov, N. Belskaya, M. Palafox, I. Kostova   +4 more
semanticscholar   +1 more source

Synthesis of heterocycles through denitrogenative cyclization of triazoles and benzotriazoles.

Chemistry, 2020
During the past decades there has been considerable growth in the development of denitrogenative reactions of triazole skeletons to construct valuable cyclic compounds, particularly heterocycles.
Wenbo Li, Junliang Zhang
semanticscholar   +1 more source

ChemInform Abstract: 1,2,4‐TRIAZOLE 20. MITT. DIE JODIERUNG VON 1,2,4‐TRIAZOL UND 1,2,3‐TRIAZOL ZU 3,5‐DIJOD‐1,2,4‐TRIAZOL BZW. 4,5‐DIJOD‐1,2,3‐TRIAZOL

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractDurch Erhitzen des Jodtriazols (I) mit dem Dimethyltriazol (II) entstehen die Jodtriazole (III) ( 15% Ausbeute) und (IV) (30%).
RALF MIETHCHEN, HELGA ALBRECHT, EDELTRAUD RACHOW   +2 more
openaire   +1 more source

Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application.

Journal of Medicinal Chemistry
Triazole demonstrates distinctive physicochemical properties, characterized by weak basicity, various dipole moments, and significant dual hydrogen bond acceptor and donor capabilities.
Qianwen Guan, Shuaishuai Xing, Lei Wang, Jiawei Zhu, Can Guo, Chunlei Xu, Qun Zhao, Yulan Wu, Yao Chen, Haopeng Sun   +9 more
semanticscholar   +1 more source

Unsymmetrical Functionalization of Bis-1,2,4-triazoles Skeleton: Exploring for Promising Energetic Materials

, 2020
Unsymmetrical functionalization of bis-1,2,4-triazoles was attempted and a series of nitrogen/oxygen-rich energetic materials were designed and synthesized in this study.
Tingou Yan, Hongwei Yang, G. Cheng
semanticscholar   +1 more source

Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua, Maialen Sagartzazu-Aizpurua, Zaira Monasterio   +2 more
openaire   +1 more source

Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents.

Journal of Natural Products, 2019
(+)-Usnic acid, a product of secondary metabolism in lichens, has displayed a broad range of biological properties such as antitumor, antimicrobial, antiviral, anti-inflammatory, and insecticidal activities. Interested by these pharmacological activities
P. Bangalore, S. K. Vagolu, R. K. Bollikanda, Dileep K. Veeragoni, P. Choudante, S. Misra, D. Sriram, B. Sridhar, S. Kantevari   +8 more
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Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides.

Angewandte Chemie, 2019
The 1,2,3-triazole group is one of the most important connective linkers and functional aromatic heterocycles in modern chemistry. The boom in growth of 1,4-disubstituted triazole products, in particular, since the early 2000's, can be largely attributed
Marie-Claire Giel, C. Smedley, Emily R. R. Mackie, Taijie Guo, Jiajia Dong, T. P. Soares da Costa, J. Moses   +6 more
semanticscholar   +1 more source