Results 331 to 340 of about 126,240 (387)

Triazole antifungals: A review

Drugs of Today, 2015
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or immunodeficiency, have been on an upward trend for numerous years. Despite advancements in antifungal medication, treatment in certain patients can still be difficult for reasons such as impaired organ function, limited administration routes or poor safety profiles of
L R, Peyton, S, Gallagher, M, Hashemzadeh   +2 more
openaire   +2 more sources

Novel triazole antifungal agents

Expert Opinion on Investigational Drugs, 2000
The risk of opportunistic infections is greatly increased in patients who are immunocompromised due to AIDS, cancer chemotherapy and organ or bone marrow transplantation. Candida albicans is often associated with serious systemic fungal infections, however other Candida species such as Candida krusei, Candida tropicalis and Candida glabrata, as well as
H L, Hoffman, E J, Ernst, M E, Klepser
openaire   +2 more sources

Synthetic Routes for 1,4-disubstituted 1,2,3-triazoles: A Review

Current organic chemistry, 2019
N-Heterocyclic compounds like 1,2,3-triazoles serve as a key scaffolds among organic compounds having diverse applications in the field of drug discovery, bioconjugation, material science, liquid crystals, pharmaceutical chemistry and solid phase organic
C. Kaushik, Jyoti Sangwan, Raj Luxmi, Krishan Kumar, Ashima Pahwa   +4 more
semanticscholar   +1 more source

1,2,4-Triazole

2006
[288-88-0] C2H3N3 (MW 69.08) InChI = 1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) InChIKey = NSPMIYGKQJPBQR-UHFFFAOYSA-N (transacylating agent used for ester and amide synthesis, especially in peptide synthesis; cyclization reactions; oligonucleotide synthesis) Physical Data: mp 120–121 °C; bp 260 °C (dec above 187 °C); fp 140 
Jean-Claude Gesquière, Christopher S. Siedem   +1 more
openaire   +1 more source

1,2,3-Triazoles. Part II. 4-Amino-5-aminomethyl-1,2,3-triazoles

Journal of the Chemical Society, Perkin Transactions 1, 1973
4-Amino-1-(and 2-)methyl-1,2,3-triazole-5-carbonitrile were made by acidic hydrolysis of 4-dimethylaminomethyleneamino-1-(and 2-)methyl-1,2,3-triazole-5-carbonitrile. These amino-nitriles, and also their known 3-methyl- and 3-benzyl-analogues, were hydrogenated to 4-amino-5-aminomethyl-1-methyl-1,2,3-triazole (1a) and its 2- and 3-methyl- and 3-benzyl ...
openaire   +2 more sources

1,2,3‐Triazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Synthesis of Triazole Nucleoside Derivatives

Nucleosides, Nucleotides & Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Zicheng, Li, Shuhua, Chen, Ning, Jiang, Gang, Cui   +3 more
openaire   +2 more sources

Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride.

Organic Letters, 2018
A regioselective metal-free preparation of 4-fluorosulfonyl 1,2,3-triazoles from organic azides and a hitherto underexplored bromovinylsulfonyl fluoride building block is described.
Joice Thomas, V. Fokin
semanticscholar   +1 more source

1,2,3-Triazoles

1974
Publisher Summary This chapter focuses on the chemistry of monocyclic1,2,3-triazoles as much of the chemistry of benzotriazoles and other fused systems has little in common with monocyclic triazole chemistry and provides a broad survey of methods of synthesis and reactions of triazoles. There has been considerable interest in 1,2,3-triazoles as light
T.L. Gilchrist, G.E. Gymer
openaire   +1 more source

Triazoles. Part VIII. 1,2,4-Triazole-3-sulphonic acids

Journal of the Chemical Society C: Organic, 1967
Free 1,2,4-triazole-3-sulphonic acids have been prepared by oxidation of the corresponding thiols with potassium permanganate or, preferably, by treatment of sulphonyl chlorides with ethanol.
A. J. Blackman, E. J. Browne, J. B. Polya   +2 more
openaire   +1 more source