Molecular insight into the viral biology and clinical features of trichodysplasia spinulosa
British Journal of Dermatology, 2016 SummaryTrichodysplasia spinulosa (TS) is a disfiguring skin disease that occurs most frequently in patients receiving immunosuppressive therapies, and is thus frequently associated with organ transplantation. TS is characterized clinically by folliculocentric papular eruption, keratin spine formation and development of leonine face; and histologically ...
J H, Wu +3 more
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Discovery and Characterization of Novel Polyomaviruses in Humans [PDF]
, 2014 The family Polyomaviridae is comprised of small, double-stranded DNA viruses of approximately 5,000 base pairs. Two polyomaviruses are well-established human pathogens and cause significant morbidity and mortality in immunocompromised patients.
Siebrasse, Erica Anne
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Development of Microsphere-based Molecular and Serodiagnostics and Their Clinical Utility [PDF]
, 2020 Microbial infections share many symptoms in common, rendering diagnosis difficult solely on clinical grounds. Thus, rapid, cost-effective and reliable tests are necessary for the diagnosis of infectious diseases. While the traditional diagnosis is mostly
Wang, Yilin
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The trichodysplasia spinulosa-associated polyomavirus : infection, pathogenesis, evolution and adaptation [PDF]
, 2015 Until a few years ago, only two human polyomaviruses (JC and BK) were known to infect humans and cause severe illness in immunocompromised hosts. Since 2007, at least eleven new polyomaviruses became known that infect humans.
Kazem, S.
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Multiple Skin Cancers in a Renal Transplant Recipient: A Patient Report with Analyses of Human Papillomavirus and Human Polyomavirus Infection [PDF]
, 2015 journal ...
100000144 +31 more
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Virology JournalBackground Merkel Cell Carcinoma (MCC) is an aggressive skin cancer that is three times deadlier than melanoma. In 2008, it was found that 80% of MCC cases are caused by the genomic integration of a novel polyomavirus, Merkel Cell Polyomavirus (MCPyV ...
Kaira R. Thevenin +4 more
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[Trichodysplasia spinulosa. Report of one case].
Revista medica de Chile, 2018 Trichodysplasia spinulosa is a rare disease that occurs in the setting of immunosuppression, associated with tolerogenic therapy used in allograft recipients or patients with hematologic malignancies. Clinically, it is characterized by a centrofacial cutaneous eruption of erythematous papules with a central keratinous spicule, often associated with ...
Cristián, Navarrete-Dechent +4 more
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Seroepidemiology and primary infections of the recently detected Merkel cell polyomavirus and trichodysplasia-spinulosa associated polyomavirus [PDF]
, 2013 Two newly found polyomaviruses are related to human skin diseases; Merkel cell polyomavirus (MCPyV), identified in Merkel cell carcinomas (MCC) is believed to be an etiologic factor in the pathogenesis of MCC; trichodysplasia spinulosa-associated ...
Chen, Tingting
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Molecular Biology and Clinical Occurrence of Emerging Human Polyomaviruses [PDF]
, 2014 Human polyomaviruses (HPyVs) are known to cause benign initial infection at an early age. They have a high prevalence in the population with frequent incidences of reactivation, and pathologic consequences in those who are elderly or immunosuppressed ...
Sadeghi, Mohammadreza
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J Acquir Immune Defic Syndr [PDF]
Background:HIV infection is associated with increased susceptibility to common pathogens which may trigger chronic antigenic stimulation and hyperactivation of B-cells, events known to precede the development of AIDS-associated non-Hodgkin lymphoma (AIDS-
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