Multiplex analysis of Human Polyomavirus diversity in kidney transplant recipients with BK virus replication [PDF]
, 2019 Background: While the pathogenicity of the two initially identified Human Polyomaviruses (HPyVs), BK Virus (BKPyV) and JC Virus (JCPyV) has been intensely studied, there is only limited data, on whether the occurrence of the recently discovered HPyVs ...
Aberle, Stephan W. +6 more
core +1 more source
Merkel Cell Polyomavirus—Pathophysiology and Treatment in the Era of Gene‐Targeted Therapies
Reviews in Medical Virology, Volume 34, Issue 5, September 2024.ABSTRACT Merkel cell polyomavirus (MCPyV) is a significant contributor to the development of Merkel cell carcinoma (MCC), an aggressive skin cancer with high recurrence and a low survival rate. In fact, it is the deadliest skin cancer. The precise routes of transmission for MCPyV‐positive MCC remain unclear, but several factors may trigger its ...
Trairong Chokwassanasakulkit +1 more
wiley +1 more source
Protein Science, Volume 33, Issue 2, February 2024.Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Emily M. Cross +10 more
wiley +1 more source
Immunobiology of Emerging Human DNA Viruses [PDF]
, 2014 Many unknown species of human DNA viruses have recently (2005-2013) been discovered by using modern molecular and bioinformatic tools. The clinical and pathogenic roles of these viruses are presently known only fragmentarily; however they were found in ...
Kumar, Arun
core
Characterization of the self-assembly of New Jersey polyomavirus VP1 into virus-like particles and the virus seroprevalence in Japan [PDF]
, 2019 浜松医科大学博士（医学）doctoral医学系研究科New Jersey polyomavirus (NJPyV) was discovered in 2014 in a pancreatic transplant recipient’s vascular endothelial cells. Here, in the recombinant baculovirus system, VP1 protein of NJPyV expressed in insect cells was processed.
10379, 周, 显凤
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Human polyomaviruses and cancer: an overview
Clinics, 2018 The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado +5 more
doaj +1 more source
A novel human polyomavirus closely related to the African green monkey-derived lymphotropic polyomavirus (LPV) [PDF]
, 2011 A novel human polyomavirus was identified with generic PCR in a kidney transplant patient under immunosuppressive treatment. Its genome was completely amplified and sequenced.
Calvignac, Sébastien +7 more
core +2 more sources
An Interesting Case Report of Trichodysplasia Spinulosa in a Case of B-cell Lymphocytic Leukemia
Indian Journal of Paediatric DermatologyTrichodysplasia spinulosa (TS) is a rare dermatologic condition characterized by follicular-based shiny papules and alopecia with characteristic histopathologic findings. This condition is unique to patients with TS-associated polyoma virus infection who
Payal H. Choithani +3 more
doaj +1 more source
Next-generation sequencing shows marked rearrangements of BK polyomavirus that favor but are not required for polyomavirus-associated nephropathy [PDF]
, 2020 Background BKPyV is associated with polyomavirus-associated nephropathy (PVAN), a major cause of graft rejection in kidney transplant recipients (KTRs).
Aberle, Stephan W. +5 more
core +1 more source
The Human Polyomavirus Middle and Alternative T-Antigens; Thoughts on Roles and Relevance to Cancer
Frontiers in Microbiology, 2018 Approximately 15–20% of human cancer is related to infection, which renders them potentially preventable by antimicrobial or antiviral therapy. Human polyomaviruses (PyVs) are relevant in this regard, as illustrated by the involvement of Merkel cell ...
Els van der Meijden, Mariet Feltkamp
doaj +1 more source