Results 71 to 80 of about 898 (155)
Prevalence of DNA of fourteen human polyomaviruses determined in blood donors
Abstract BACKGROUND Human polyomaviruses (HPyVs), like herpesviruses, cause persistent infection in a large part of the population. In immunocompromised and elderly patients, PyVs cause severe diseases such as nephropathy (BK polyomavirus [BKPyV]), progressive multifocal leukoencephalopathy (JC polyomavirus [JCPyV]), and skin cancer (Merkel cell ...
Sergio Kamminga +4 more
wiley +1 more source
Elements of morphology: Standard terminology for the teeth and classifying genetic dental disorders
Abstract Dental anomalies occur frequently in a number of genetic disorders and act as major signs in diagnosing these disorders. We present definitions of the most common dental signs and propose a classification usable as a diagnostic tool by dentists, clinical geneticists, and other health care providers.
Muriel de La Dure‐Molla +24 more
wiley +1 more source
Human polyomavirus 6 and 7 are associated with pruritic and dyskeratotic dermatoses [PDF]
Background: Human Polyomavirus 6 (HPyV6) and Human Polyomavirus 7 (HPyV7) are shed chronically from human skin. HPyV7, but not HPyV6, has been linked to a pruritic skin eruption of immunosuppression.
Buck, Christopher B. +11 more
core +1 more source
Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches
JC and BK polyomaviruses were discovered over 40 years ago and have become increasingly prevalent causes of morbidity and mortality in a variety of distinct, immunocompromised patient cohorts. The recent discoveries of eight new members of the Polyomaviridae family that are capable of infecting humans suggest that there are more to be discovered and ...
Cillian F. De Gascun +2 more
wiley +1 more source
Comparing Effects of BK Virus Agnoprotein and Herpes Simplex‐1 ICP47 on MHC‐I and MHC‐II Expression
Background. Among human polyomaviruses, only BK virus (BKV) and JC virus (JCV) encode an agnoprotein upstream of VP1 on the viral late transcript. BKV agnoprotein is abundantly expressed late in the viral life cycle, but specific cellular and humoral immune responses are low or absent.
Michela Cioni +4 more
wiley +1 more source
The Role of Viruses in Cellular Transformation and Cancer
ABSTRACT Background Viral infections are established contributors to oncogenesis, leading to significant public health challenges. This systematic review aims to synthesize current knowledge on the mechanisms of viral cellular transformation and their association with various cancers.
Donath Damian
wiley +1 more source
Review on the Relationship between Human Polyomaviruses‐Associated Tumors and Host Immune System
The polyomaviruses are small DNA viruses that can establish latency in the human host. The name polyomavirus is derived from the Greek roots poly‐, which means “many,” and ‐oma, which means “tumours.” These viruses were originally isolated in mouse (mPyV) and in monkey (SV40).
Serena Delbue +3 more
wiley +1 more source
Follicular spicules of multiple myeloma [PDF]
Follicular spicules are a very rare but highly characteristic cutaneous manifestation of multiple myeloma. The spicules typically appear as hyperkeratotic horns in the follicular openings of the face, most commonly on or around the nose and forehead. The
Manabat-Hidalgo, Catherine +1 more
core
Pleomorphic adenoma (PA) is a benign salivary gland tumour that may recur or undergo malignant transformation (CXPA). Toll‐like receptors (TLR) mediate immune responses triggered by various agents such as viruses and are related to tumour formation either by stimulating or suppressing their growth, with variation across different tumour entities.
Maria K. Jauhiainen +8 more
wiley +1 more source
Human Polyomaviruses in Skin Diseases
Polyomaviruses are a family of small, nonenveloped viruses with a circular double‐stranded DNA genome of ~5,000 base pairs protected by an icosahedral protein structure. So far, members of this family have been identified in birds and mammals. Until 2006, BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) were the only polyomaviruses known to ...
Ugo Moens +3 more
wiley +1 more source

