Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient. [PDF]
PLoS Pathogens, 2010 The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden +5 more
doaj +3 more sources
Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids. [PDF]
PLoS Pathogens, 2015 Trichodysplasia spinulosa-associated Polyomavirus (TSPyV) was isolated from a patient suffering from trichodysplasia spinulosa, a skin disease that can appear in severely immunocompromised patients.
Luisa J Ströh +6 more
doaj +4 more sources
Merkel cell polyomavirus and
BMC Infectious Diseases, 2012 Background Merkel cell polyomavirus (MCPyV) and trichodysplasia spinulosa-associated polyomavirus (TSPyV) are recently found pathogens causing two rare skin disorders, Merkel cell carcinoma (MCC) and trichodysplasia spinulosa (TS).
Sadeghi Mohammadreza +7 more
doaj +5 more sources
Dermatoscopy case of the month: Trichodysplasia spinulosaKey message [PDF]
JAAD Case Reports, 2021 Connor J. Stonesifer, BA +3 more
doaj +5 more sources
Polyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21. [PDF]
PLoS ONE, 2014 Trichodysplasia spinulosa (TS) is a proliferative skin disease observed in severely immunocompromized patients. It is characterized by papule and trichohyalin-rich spicule formation, epidermal acanthosis and distention of dysmorphic hair follicles ...
Siamaque Kazem +7 more
doaj +4 more sources
Pediatric trichodysplasia spinulosa in skin of color [PDF]
JAAD Case ReportsCatherine Laferté, MD +5 more
doaj +4 more sources
Trichodysplasia Spinulosa. [PDF]
Sultan Qaboos Univ Med J, 2023 Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases.
Khalili AA +3 more
europepmc +5 more sources
Trichodysplasia Spinulosa in a 71-year-old Heart Transplant Recipient [PDF]
Dermatology Practical & Conceptual, 2023 Maulik Dhandha +2 more
doaj +4 more sources
Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes [PDF]
Viruses, 2015 Recombinant virus-like particles (VLPs) represent a promising tool for protein engineering. Recently, trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) was efficiently produced in yeast expression system and shown to self ...
Alma Gedvilaite +6 more
doaj +4 more sources
Trichodysplasia spinulosa: a comprehensive review of the disease and its treatment. [PDF]
J Eur Acad Dermatol Venereol, 2021 AbstractTrichodysplasia spinulosa (TS) is a rare dermatological disease caused by TS‐associated polyomavirus (TSPyV) in immunosuppressed patients. The seroprevalence of TSPyV in immunocompetent adults is high and the number of immunosuppressed patients developing TS remains low, suggesting that TS is underdiagnosed and/or that additional unknown ...
Curman P, Näsman A, Brauner H.
europepmc +5 more sources