Results 31 to 40 of about 1,896 (142)

Trichodysplasia Spinulosa

open access: yesTransplantation, 2017
Rachel K, Rosenstein   +2 more
core   +5 more sources

Management of Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Patient With Topical Cidofovir and Oral Leflunomide. [PDF]

open access: yesPediatr Transplant
ABSTRACT Background This case report describes a 10‐year‐old male with a history of kidney transplantation who developed trichodysplasia spinulosa (TS), a rare skin disorder associated with immunosuppression. Methods The patient's condition, characterized by follicular papules and keratinous spines primarily on the face, was managed by a ...
Hansen AM   +4 more
europepmc   +2 more sources

Merkel cell polyomavirus–negative Merkel cell carcinoma is associated with JAK‐STAT and MEK‐ERK pathway activation

open access: yesCancer Science, Volume 113, Issue 1, Page 251-260, January 2022., 2022
This study investigates the relationship between Merkel cell polyomavirus (MCPyV) status and activation of the MEK‐ERK and JAK‐STAT signaling pathways in Merkel cell carcinoma (MCC). We observed that activation of the JAK2 and MEK‐ERK pathways was more prevalent in MCPyV‐negative than in MCPyV‐positive MCC, leading us to conclude that MCC tumorigenic ...
Takeshi Iwasaki   +7 more
wiley   +1 more source

A Case Report of Purtscher‐Like Retinopathy Secondary to Pneumocystis jirovecii Pneumonia in an Immunocompromised Patient

open access: yesCase Reports in Ophthalmological Medicine, Volume 2022, Issue 1, 2022., 2022
To the best of our knowledge, we present the first case of a young adult male, on long‐term immunosuppressive therapy following a live‐donor kidney transplant, with Purtscher‐like retinopathy (PLR) secondary to Pneumocystis jirovecii pneumonia (PCP).
Alastair David Bezzina   +2 more
wiley   +1 more source

Immune sensing of mouse polyomavirus DNA by p204 and cGAS DNA sensors

open access: yesThe FEBS Journal, Volume 288, Issue 20, Page 5964-5985, October 2021., 2021
During mouse polyomavirus infection, DNA sensor, p204, senses viral genomes in the nucleus while cGAS senses leaked viral genomes in the cytosol and micronucleus‐like bodies. DNA sensing induces interferon‐beta production via STING‐IRF3 pathway. ​ The mechanism by which DNA viruses interact with different DNA sensors and their connection with the ...
Boris Ryabchenko   +4 more
wiley   +1 more source

Cutaneous viral infections associated with ultraviolet radiation exposure

open access: yesInternational Journal of Cancer, Volume 148, Issue 2, Page 448-458, 15 January 2021., 2021
Abstract The complex interplay between ultraviolet radiation (UVR) and cutaneous viral infections in the context of cancer etiology is challenging to unravel, given the limited information on the independent association between UVR and cutaneous viral infections.
Yayi Zhao   +13 more
wiley   +1 more source

Trichodysplasia Spinulosa in a Japanese Pediatric Patient. [PDF]

open access: yesJ Dermatol
Tomita K   +8 more
europepmc   +2 more sources

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