Results 31 to 40 of about 898 (155)

Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient. [PDF]

PLoS Pathogens, 2010
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden, René W A Janssens, Chris Lauber, Jan Nico Bouwes Bavinck, Alexander E Gorbalenya, Mariet C W Feltkamp   +5 more
doaj   +2 more sources

Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids. [PDF]

PLoS Pathogens, 2015
Trichodysplasia spinulosa-associated Polyomavirus (TSPyV) was isolated from a patient suffering from trichodysplasia spinulosa, a skin disease that can appear in severely immunocompromised patients.
Luisa J Ströh, Gretchen V Gee, Bärbel S Blaum, Aisling S Dugan, Mariet C W Feltkamp, Walter J Atwood, Thilo Stehle   +6 more
doaj   +2 more sources

Polyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21. [PDF]

PLoS ONE, 2014
Trichodysplasia spinulosa (TS) is a proliferative skin disease observed in severely immunocompromized patients. It is characterized by papule and trichohyalin-rich spicule formation, epidermal acanthosis and distention of dysmorphic hair follicles ...
Siamaque Kazem, Els van der Meijden, Richard C Wang, Arlene S Rosenberg, Elena Pope, Taylor Benoit, Philip Fleckman, Mariet C W Feltkamp   +7 more
doaj   +2 more sources

Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus. [PDF]

J Cutan Pathol, 2011
Trichodysplasia spinulosa (TS) is a folliculocentric and clinically papular dermatological disorder occurring in the setting of immunosuppression typically in association with solid organ transplantation or hematolymphoid malignancies. We report the occurrence of TS in a 7-year-old girl with Down syndrome and pre-B-acute lymphoblastic leukemia who was ...
Matthews MR, Wang RC, Reddick RL, Saldivar VA, Browning JC.   +4 more
europepmc   +4 more sources

Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes [PDF]

Viruses, 2015
Recombinant virus-like particles (VLPs) represent a promising tool for protein engineering. Recently, trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) was efficiently produced in yeast expression system and shown to self ...
Alma Gedvilaite, Indre Kucinskaite-Kodze, Rita Lasickiene, Albertas Timinskas, Ausra Vaitiekaite, Danguole Ziogiene, Aurelija Zvirbliene   +6 more
doaj   +2 more sources

Polyomavirus Associated Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Recipient. [PDF]

Pediatr Transplant
ABSTRACT Background Trichodysplasia spinulosa (TS) is an inconspicuous cutaneous infection caused by a distinct polyoma virus affecting the immunocompromised host. TS is rare in children and can masquerade as other dermatological conditions, causing a delay in diagnosis.
Pande N, Leblanc P, Miedzybrodzki B, Carlos M, Maedler-Kron C, Karatzios C, Gaudreault-Tremblay MM, Downie ML.   +7 more
europepmc   +3 more sources

Photodynamic therapy for the treatment of trichodysplasia spinulosa in an Asian renal transplant recipient: A case report and review of literature [PDF]

JAAD Case Reports, 2021
Yasmin Chia Chia Liew, MBChB, MRCP, Terence Yi Shern Kee, MBBS, MRCP, FAMS, FRCP, FASN, Jia Liang Kwek, MBBS, MRCP, FAMS, Po Yin Tang, MBBS, BMedSc, FRCPA, FRCPath, Choon Chiat Oh, MBBS, MSc, FRCP, FAMS   +4 more
doaj   +2 more sources

A rare case of viral-associated trichodysplasia spinulosa in a patient with chronic lymphocytic leukemia [PDF]

International Journal of Women's Dermatology, 2023
Rachel Choi, MD, Shaman Bhullar, BA, Jennifer McNiff, MD, Justin Persico, MD, Jonathan Leventhal, MD   +4 more
doaj   +2 more sources

Trichodysplasia spinulosa treated with intravenous cidofovir in a patient with a heart transplant and chronic kidney disease [PDF]

JAAD Case Reports, 2023
Benjamin Eduardo Swaby, MS, Camila Ortiz, MD, MEd, Keily Ortega, BS, Debra Tucker, BA, Alaina J. James, MD, PhD   +4 more
doaj   +2 more sources

Management of Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Patient With Topical Cidofovir and Oral Leflunomide. [PDF]

Pediatr Transplant
ABSTRACT Background This case report describes a 10‐year‐old male with a history of kidney transplantation who developed trichodysplasia spinulosa (TS), a rare skin disorder associated with immunosuppression. Methods The patient's condition, characterized by follicular papules and keratinous spines primarily on the face, was managed by a ...
Hansen AM, Mehra S, Bowen AR, Sherbotie J, Cipriano SD.   +4 more
europepmc   +2 more sources