Results 51 to 60 of about 7,894 (140)

Merkel Cell Polyomavirus—Pathophysiology and Treatment in the Era of Gene‐Targeted Therapies

Reviews in Medical Virology, Volume 34, Issue 5, September 2024.
ABSTRACT Merkel cell polyomavirus (MCPyV) is a significant contributor to the development of Merkel cell carcinoma (MCC), an aggressive skin cancer with high recurrence and a low survival rate. In fact, it is the deadliest skin cancer. The precise routes of transmission for MCPyV‐positive MCC remain unclear, but several factors may trigger its ...
Trairong Chokwassanasakulkit, Nigel A. J. McMillan   +1 more
wiley   +1 more source

Resolution of painful trichodysplasia spinulosa with topical cidofovir: case report

Journal of Dermatological Treatment
Purpose: Trichodysplasia spinulosa (TS) is a rare, disfiguring skin condition which presents with widespread asymptomatic or pruritic, skin-colored papules with white protruding keratin spiculations in immunocompromised individuals.
Kevin M. Burningham, Ritu N. Swali, Peter L. Rady, Anisha B. Patel, Stephen K. Tyring   +4 more
doaj   +1 more source

A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin α‐dependent nuclear localization signals

Protein Science, Volume 33, Issue 2, February 2024.
Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Emily M. Cross, Nasim Akbari, Hanieh Ghassabian, Mikayla Hoad, Silvia Pavan, Daryl Ariawan, Camilla M. Donnelly, Enrico Lavezzo, Gayle F. Petersen, Jade K. Forwood, Gualtiero Alvisi   +10 more
wiley   +1 more source

The trichodysplasia spinulosa-associated polyomavirus : discovery - prevalence - infection - expression [PDF]

, 2016
  In dit proefschrift wordt de ontdekking van een nieuw polyomavirus beschreven, trichodysplasia spinulosa-associated polyomavirus (TSPyV).
Meijden, P.Z. van der
core  

Characterizing determinants of BK Polyomavirus-specific immune response [PDF]

, 2016
BK polyomavirus (BKPyV) is one of now 13 human polyomavirus (HPyV) species detected in humans. BKPyV is only known to infect humans and seroprevalence rates of more than 90% have been reported in adult populations around the world.
Cioni, Michela
core   +1 more source

Characterization of T Antigens, Including Middle T and Alternative T, Expressed by the Human Polyomavirus Associated with Trichodysplasia Spinulosa [PDF]

Journal of Virology, 2015
ABSTRACT The polyomavirus tumor (T) antigens play crucial roles in viral replication, transcription, and cellular transformation. They are encoded by partially overlapping open reading frames (ORFs) located in the early region through alternative mRNA splicing. The T expression pattern of the trichodysplasia spinulosa-associated polyomavirus (
Meijden, E. van der, Kazem, S., Dargel, C.A., Vuren, N. van, Hensbergen, P.J., Feltkamp, M.C.W.   +5 more
openaire   +5 more sources

Trichodysplasia spinulosa--a newly described folliculocentric viral infection in an immunocompromised host. [PDF]

, 1999
This is a case report of an immunocompromised individual who presented with progressive alopecia, friable follicular spinous processes, and erythematous, indurated papules.
Howell, D N, Fleckman, P, Kim, S, Haycox, C L, Sundberg, J P, Miller, S E, Smith, L T, Piepkorn, M   +7 more
core   +2 more sources

Viral-Associated Trichodysplasia: Characterization of a Novel Polyomavirus Infection With Therapeutic Insights [PDF]

, 2012
Background Viral-associated trichodysplasia of immunosuppression is a rare cutaneous eruption that is characterized by follicularly based shiny papules and alopecia with characteristic histopathologic findings of abnormally anagen follicules with ...
Wanat, Karolyn A, Rosenbach, Misha, Dentchev, Tzvete, Simbiri, Kenneth O, Robertson, Erle, Holler, Phillip D, Seykora, John J   +6 more
core   +1 more source

An Interesting Case Report of Trichodysplasia Spinulosa in a Case of B-cell Lymphocytic Leukemia

Indian Journal of Paediatric Dermatology
Trichodysplasia spinulosa (TS) is a rare dermatologic condition characterized by follicular-based shiny papules and alopecia with characteristic histopathologic findings. This condition is unique to patients with TS-associated polyoma virus infection who
Payal H. Choithani, Meghana Chandrashekhar Rane, Dipti Thakur, Vidya D Kharkar   +3 more
doaj   +1 more source

The Pacific lineage (2E) of JC polyomavirus is prevalent in Sumba Island, Eastern Indonesia [PDF]

, 2008
Recent studies have identified a Pacific lineage (2E) of JC polyomavirus (also designated as JC virus or JCV) that occurs in both Island Southeast Asia and Oceania, but not in mainland Asia.
Nakazawa, Minato, Soemantri, Augustinus, Shimizu, Hana, Ohtsuka, Ryutaro, Shan, Zhong, Kitamura, Tadaichi, Shibuya, Ayako, Ishida, Takafumi, Yogo, Yoshiaki, Sekiyama, Makiko, Takasaka, Tomokazu, Ikegaya, Hiroshi   +11 more
core   +2 more sources