Results 31 to 40 of about 7,894 (140)

Trichodysplasia Spinulosa. [PDF]

open access: yesSultan Qaboos Univ Med J, 2023
Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus.
Khalili AA   +3 more
europepmc   +2 more sources

Seroepidemiology of the Newly Found Trichodysplasia Spinulosa–Associated Polyomavirus [PDF]

open access: yesThe Journal of Infectious Diseases, 2011
Trichodysplasia spinulosa (TS)-associated polyomavirus (TSV) was recently (in 2010) discovered in TS lesions. To investigate the seroprevalence and primary exposure time of this virus, we set up a virus protein (VP1) viruslike particle (VLP)-based immunoglobulin G enzyme immunoassay.
Ruuskanen Olli   +9 more
openaire   +3 more sources

Merkel cell polyomavirus–negative Merkel cell carcinoma is associated with JAK‐STAT and MEK‐ERK pathway activation

open access: yesCancer Science, Volume 113, Issue 1, Page 251-260, January 2022., 2022
This study investigates the relationship between Merkel cell polyomavirus (MCPyV) status and activation of the MEK‐ERK and JAK‐STAT signaling pathways in Merkel cell carcinoma (MCC). We observed that activation of the JAK2 and MEK‐ERK pathways was more prevalent in MCPyV‐negative than in MCPyV‐positive MCC, leading us to conclude that MCC tumorigenic ...
Takeshi Iwasaki   +7 more
wiley   +1 more source

Immune sensing of mouse polyomavirus DNA by p204 and cGAS DNA sensors

open access: yesThe FEBS Journal, Volume 288, Issue 20, Page 5964-5985, October 2021., 2021
During mouse polyomavirus infection, DNA sensor, p204, senses viral genomes in the nucleus while cGAS senses leaked viral genomes in the cytosol and micronucleus‐like bodies. DNA sensing induces interferon‐beta production via STING‐IRF3 pathway. ​ The mechanism by which DNA viruses interact with different DNA sensors and their connection with the ...
Boris Ryabchenko   +4 more
wiley   +1 more source

Cutaneous viral infections associated with ultraviolet radiation exposure

open access: yesInternational Journal of Cancer, Volume 148, Issue 2, Page 448-458, 15 January 2021., 2021
Abstract The complex interplay between ultraviolet radiation (UVR) and cutaneous viral infections in the context of cancer etiology is challenging to unravel, given the limited information on the independent association between UVR and cutaneous viral infections.
Yayi Zhao   +13 more
wiley   +1 more source

Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus [PDF]

open access: yesJournal of Cutaneous Pathology, 2011
Trichodysplasia spinulosa (TS) is a folliculocentric and clinically papular dermatological disorder occurring in the setting of immunosuppression typically in association with solid organ transplantation or hematolymphoid malignancies. We report the occurrence of TS in a 7-year-old girl with Down syndrome and pre-B-acute lymphoblastic leukemia who was ...
Mark R, Matthews   +4 more
openaire   +2 more sources

Trichodysplasia spinulosa-associated polyomavirus, a bristly bug

open access: yes, 2013
Molecular basis of virus replication, viral pathogenesis and antiviral ...
Feltkamp, M.
openaire   +2 more sources

Seroprevalence of fourteen human polyomaviruses determined in blood donors. [PDF]

open access: yesPLoS ONE, 2018
The polyomavirus family currently includes thirteen human polyomavirus (HPyV) species. In immunocompromised and elderly persons HPyVs are known to cause disease, such as progressive multifocal leukoencephalopathy (JCPyV), haemorrhagic cystitis and ...
Sergio Kamminga   +3 more
doaj   +1 more source

Specific Detection of Trichodysplasia Spinulosa–Associated Polyomavirus DNA in Skin and Renal Allograft Tissues in a Patient With Trichodysplasia Spinulosa [PDF]

open access: yesArchives of Dermatology, 2012
Trichodysplasia spinulosa (TS) is a rare, disfiguring skin condition that affects immunosuppressed patients, universally involving the central face. New data point to the recently discovered TS-associated polyomavirus (TSPyV) as the causative agent.We report a case of TS in a 48-year-old African American man after renal transplant; via polymerase chain
Max K, Fischer   +6 more
openaire   +2 more sources

Rapid Detection of Trichodysplasia Spinulosa-Associated Polyomavirus in Skin Biopsy Specimen [PDF]

open access: yesGenome Announcements, 2014
ABSTRACT Trichodysplasia spinulosa-associated polyomavirus (TSV) is responsible for a rare skin cancer. Using metagenomic approaches, we determined the complete genome sequence of a TSV first detected in Brazil in spicules of an immunocompromised patient suspected to have trichodysplasia spinulosa.
Urbano, Paulo Roberto P.   +4 more
openaire   +2 more sources

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