Results 11 to 20 of about 7,894 (140)

Seroprevalence of Trichodysplasia Spinulosa–associated Polyomavirus

Emerging Infectious Diseases, 2011
We identified a new polyomavirus in skin lesions from a patient with trichodysplasia spinulosa (TS). Apart from TS being an extremely rare disease, little is known of its epidemiology.
Els van der Meijden, Siamaque Kazem, Manda M. Burgers, Rene Janssens, Jan Nico Bouwes Bavinck, Hester E. de Melker, Mariet C.W. Feltkamp   +6 more
doaj   +8 more sources

Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient.

PLoS Pathogens, 2010
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden, René W A Janssens, Chris Lauber, Jan Nico Bouwes Bavinck, Alexander E Gorbalenya, Mariet C W Feltkamp   +5 more
doaj   +6 more sources

Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids. [PDF]

PLoS Pathogens, 2015
Trichodysplasia spinulosa-associated Polyomavirus (TSPyV) was isolated from a patient suffering from trichodysplasia spinulosa, a skin disease that can appear in severely immunocompromised patients.
Luisa J Ströh, Gretchen V Gee, Bärbel S Blaum, Aisling S Dugan, Mariet C W Feltkamp, Walter J Atwood, Thilo Stehle   +6 more
doaj   +7 more sources

Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus DNAs and antibodies in blood among the elderly [PDF]

BMC Infectious Diseases, 2012
Background Merkel cell polyomavirus (MCPyV) and trichodysplasia spinulosa-associated polyomavirus (TSPyV) are recently found pathogens causing two rare skin disorders, Merkel cell carcinoma (MCC) and trichodysplasia spinulosa (TS).
Sadeghi Mohammadreza, Aronen Matti, Chen Tingting, Jartti Laura, Jartti Tuomas, Ruuskanen Olli, Söderlund-Venermo Maria, Hedman Klaus   +7 more
doaj   +9 more sources

Polyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21. [PDF]

PLoS ONE, 2014
Trichodysplasia spinulosa (TS) is a proliferative skin disease observed in severely immunocompromized patients. It is characterized by papule and trichohyalin-rich spicule formation, epidermal acanthosis and distention of dysmorphic hair follicles ...
Siamaque Kazem, Els van der Meijden, Richard C Wang, Arlene S Rosenberg, Elena Pope, Taylor Benoit, Philip Fleckman, Mariet C W Feltkamp   +7 more
doaj   +7 more sources

Trichodysplasia spinulosa: a presentation of polyomavirus infection in immunosuppressed patients [PDF]

Dermatology Online Journal, 2022
Trichodysplasia spinulosa (TS) is a rare skin condition that occurs mainly in immunosuppressed patients. Although initially postulated to be an adverse effect of immunosuppressants, TS-associated polyomavirus (TSPyV) has since been isolated from TS lesions and is now considered to be the causative agent.
Ji-Xu, Antonio, Artounian, Kimberly, Fung, Maxwell A, Burrall, Barbara A   +3 more
openaire   +5 more sources

Trichodysplasia spinulosa post kidney transplant. [PDF]

Clin Case Rep
Trichodysplasia spinulosa: a rare viral skin disease caused by the trichodysplasia spinulosa‐associated polyomavirus (TSPyV) affecting immunosuppressed individuals. Key Clinical Message Trichodysplasia spinulosa is a rare dermatological condition caused by a virus that predominantly affects immunosuppressed individuals.
Cabeza Rivera F, Ortigosa Serrano VA, Medina AM, Esmail R.   +3 more
europepmc   +3 more sources

Polyomavirus Associated Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Recipient [PDF]

Pediatric Transplantation
ABSTRACT Background Trichodysplasia spinulosa (TS) is an inconspicuous cutaneous infection caused by a distinct polyoma virus affecting the immunocompromised host. TS is rare in children and can masquerade as other dermatological conditions, causing a delay in diagnosis.
Mallory L Downie, Nivedita Pande, Marie-Michele Gaudreault-Tremblay   +2 more
exaly   +4 more sources

Primary Polyomavirus Infection, Not Reactivation, as the Cause of Trichodysplasia Spinulosa in Immunocompromised Patients [PDF]

Journal of Infectious Diseases, 2016
Classic human polyomaviruses (JC and BK viruses) become pathogenic when reactivating from latency. For the rare skin disease trichodysplasia spinulosa, we show that manifestations of the causative polyomavirus (TSPyV) occur during primary infection of the immunosuppressed host.
Meijden, E. van der, Horvath, B., Nijland, M., Vries, K. de, Raez, E., Diercks, G.F., Weerd, A.E. de, Clahsen-van Groningen, M.C., Blij-de Brouwer, C.S. van der, Zon, A.J. van der, Kroes, A.C.M., Hedman, K., Kampen, J.J.A. van, Riezebos-Brilman, A., Feltkamp, M.C.W.   +14 more
openaire   +8 more sources

Serological cross-reactivity between Merkel cell polyomavirus and two closely related chimpanzee polyomaviruses. [PDF]

PLoS ONE, 2014
Phylogenetic analyses based on the major capsid protein sequence indicate that Merkel cell polyomavirus (MCPyV) and chimpanzee polyomaviruses (PtvPyV1, PtvPyV2), and similarly Trichodysplasia spinulosa-associated polyomavirus (TSPyV) and the orangutan ...
Jérôme T J Nicol, Etienne Liais, Romain Potier, Elisa Mazzoni, Mauro Tognon, Pierre Coursaget, Antoine Touzé   +6 more
doaj   +4 more sources