Results 31 to 40 of about 1,730 (164)
Transcription‐independent functions of p53 in DNA repair pathway selection
BioEssays, Volume 45, Issue 1, January 2023., 2023 Transcription‐independent early recruitment and PARylation of p53 at DNA damage sites promotes the recruitment of particular repair factors (e.g. DDB1 and 53BP1) and thereby tipping the balance of repair pathway selection. Abstract Recently discovered transcription‐independent features of p53 involve the choice of DNA damage repair pathway after ...
Yu‐Hsiu Wang, Michael P. Sheetz
wiley +1 more source
Comparative genomics of neuroglobin reveals its early origins. [PDF]
PLoS ONE, 2012 Neuroglobin (Ngb) is a hexacoordinated globin expressed mainly in the central and peripheral nervous system of vertebrates. Although several hypotheses have been put forward regarding the role of neuroglobin, its definite function remains uncertain.
Jasmin Dröge +3 more
doaj +1 more source
Tropical Medicine and Infectious Disease, 2021 In 2009, apicortin was identified in silico as a characteristic protein of apicomplexans that also occurs in the placozoa, Trichoplax adhaerens. Since then, it has been found that apicortin also occurs in free-living cousins of apicomplexans (chromerids)
Ferenc Orosz
doaj +1 more source
Field Biology of Placozoans (Trichoplax) [PDF]
Integrative and Comparative Biology, 2007 The goal of this review is to highlight what little is known, and point to the bulk of what is yet to be learned, about the natural history of placozoans in the field-in order to stimulate a broader search for placozoans and a fuller exploration of their distribution, diversity, and all other aspects of their enigmatic lives.
Pearse, Vicki Buchsbaum, Voigt, Oliver
openaire +3 more sources
Comparative genomics of large mitochondria in placozoans.
PLoS Genetics, 2007 The first sequenced mitochondrial genome of a placozoan, Trichoplax adhaerens, challenged the conventional wisdom that a compact mitochondrial genome is a common feature among all animals.
Ana Y Signorovitch +2 more
doaj +1 more source
Non-coding RNA annotation of the genome of Trichoplax adhaerens [PDF]
Nucleic Acids Research, 2009 A detailed annotation of non-protein coding RNAs is typically missing in initial releases of newly sequenced genomes. Here we report on a comprehensive ncRNA annotation of the genome of Trichoplax adhaerens, the presumably most basal metazoan whose genome has been published to-date.
Hertel, Jana +7 more
openaire +4 more sources
Genome-wide analysis of transposable elements and tandem repeats in the compact placozoan genome
Biology Direct, 2010 The placozoan Trichoplax adhaerens has a compact genome with many primitive eumetazoan characteristics. In order to gain a better understanding of its genome architecture, we conducted a detailed analysis of repeat content in this genome.
Meyer Eli +3 more
doaj +1 more source
Communications Biology, 2023 ASIC channels are bilaterian proton-gated sodium channels belonging to the large and functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated channels.
Wassim Elkhatib +7 more
doaj +1 more source
Trichoplax adhaerens reveals a network of nuclear receptors sensitive to 9-cis-retinoic acid at the base of metazoan evolution [PDF]
PeerJ, 2017 Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria.
Jan Philipp Novotný +9 more
doaj +2 more sources
Innate immunity in the simplest animals – placozoans
BMC Genomics, 2019 Background Innate immunity provides the core recognition system in animals for preventing infection, but also plays an important role in managing the relationship between an animal host and its symbiont.
Kai Kamm, Bernd Schierwater, Rob DeSalle
doaj +1 more source