Results 31 to 40 of about 1,756 (166)

Function and phylogeny support the independent evolution of an ASIC-like Deg/ENaC channel in the Placozoa

Communications Biology, 2023
ASIC channels are bilaterian proton-gated sodium channels belonging to the large and functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated channels.
Wassim Elkhatib, Luis A. Yanez-Guerra, Tatiana D. Mayorova, Mark A. Currie, Anhadvir Singh, Maria Perera, Julia Gauberg, Adriano Senatore   +7 more
doaj   +1 more source

A pre-metazoan origin of the CRK gene family and co-opted signaling network. [PDF]

, 2016
CRK and CRKL adapter proteins play essential roles in development and cancer through their SRC homology 2 and 3 (SH2 and SH3) domains. To gain insight into the origin of their shared functions, we have investigated their evolutionary history.
Akira IMAMOTO, Elina KOSTYANOVSKAYA, IMAMOTO Akira, Jana PAWLAK, Jody WESTBROOK, Junya YAMAGISHI, KASAI Takuma, KI Sewon, KIGAWA Takanori, KOSTYANOVSKAYA Elina, Makoto TAIJI, Mariko OKADA, Noriaki OKIMOTO, OKADA Mariko, OKIMOTO Noriaki, PAWLAK Jana, SATTA Yoko, Sewon KI, SHIGENO-NAKAZAWA Yoko, TAIJI Makoto, Takanori KIGAWA, Takuma KASAI, WESTBROOK Jody, YAMAGISHI Junya, Yoko SATTA, Yoko SHIGENO-NAKAZAWA   +25 more
core   +2 more sources

Trichoplax adhaerens reveals a network of nuclear receptors sensitive to 9-cis-retinoic acid at the base of metazoan evolution [PDF]

PeerJ, 2017
Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria.
Jan Philipp Novotný, Ahmed Ali Chughtai, Markéta Kostrouchová, Veronika Kostrouchová, David Kostrouch, Filip Kaššák, Radek Kaňa, Bernd Schierwater, Marta Kostrouchová, Zdenek Kostrouch   +9 more
doaj   +2 more sources

Identification, distribution and molecular evolution of the pacifastin gene family in Metazoa [PDF]

, 2009
BACKGROUND: Members of the pacifastin family are serine peptidase inhibitors, most of which are produced as multi domain precursor proteins. Structural and biochemical characteristics of insect pacifastin-like peptides have been studied intensively, but ...
Breugelmans, B, Broeck, JV, Simonet, G, van Hoef, V, Van Soest, S   +4 more
core   +3 more sources

Innate immunity in the simplest animals – placozoans

BMC Genomics, 2019
Background Innate immunity provides the core recognition system in animals for preventing infection, but also plays an important role in managing the relationship between an animal host and its symbiont.
Kai Kamm, Bernd Schierwater, Rob DeSalle
doaj   +1 more source

Independent elaboration of steroid hormone signaling pathways in Metazoans [PDF]

, 2009
Steroid hormones regulate many physiological processes in vertebrates, nematodes and arthropods through binding to nuclear receptors (NR), a metazoan-specific family of ligand-activated transcription factors.
Barbara A. Demeneix, Chantal Dauphin-Villemant, Gabriel V. Markov, Michael E. Baker, Raquel Tavares, Vincent Laudet   +5 more
core   +4 more sources

Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2

, 2019
Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans(1,2). Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location and interactions with their host(3-6). We
Dubilier, N., Gruber-Vodicka, H., Hadfield, M., Hinzke, T., Kleiner, M., Leisch, N., Liebeke, M., McFall-Ngai, M.   +7 more
core   +1 more source

Expansion microscopy in Placozoa: improving resolution and preservation of fragile samples during marine expedition

Frontiers in Marine Science
Placozoa are small disc-shaped animals representing one of the early branching metazoan lineages with only a dozen cell types, fast effector reactions, and complex behaviors.
Daria Y. Romanova, Yana A. Frank, Leonid L. Moroz, Leonid L. Moroz   +3 more
doaj   +1 more source

Early evolution of the LIM homeobox gene family

BMC Biology, 2010
Background LIM homeobox (Lhx) transcription factors are unique to the animal lineage and have patterning roles during embryonic development in flies, nematodes and vertebrates, with a conserved role in specifying neuronal identity.
Degnan Bernard M, Chapman Jarrod, Mohanty Kareshma, Lu Daniel R, Larroux Claire, Srivastava Mansi, Rokhsar Daniel S   +6 more
doaj   +1 more source

Deep RNA sequencing reveals the smallest known mitochondrial micro exon in animals: The placozoan cox1 single base pair exon. [PDF]

PLoS ONE, 2017
The phylum Placozoa holds a key position for our understanding of the evolution of mitochondrial genomes in Metazoa. Placozoans possess large mitochondrial genomes which harbor several remarkable characteristics such as a fragmented cox1 gene and trans ...
Hans-Jürgen Osigus, Michael Eitel, Bernd Schierwater   +2 more
doaj   +1 more source