Results 51 to 60 of about 1,730 (164)

Global diversity of the Placozoa.

PLoS ONE, 2013
The enigmatic animal phylum Placozoa holds a key position in the metazoan Tree of Life. A simple bauplan makes it appear to be the most basal metazoan known and genetic evidence also points to a position close to the last common metazoan ancestor ...
Michael Eitel, Hans-Jürgen Osigus, Rob DeSalle, Bernd Schierwater   +3 more
doaj   +1 more source

Beyond the Secretory Pathway: New Insights Into Protein Release

Traffic, Volume 26, Issue 10-12, October/December 2025.
While proteins bearing N‐terminal signal or leader sequences are secreted via the ER‐Golgi‐plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling sequence can be secreted via poorly defined mechanisms termed Unconventional Protein Secretion (UcPS).
Ruey‐Hwa Chen, Antonio J. Costa‐Filho, Jayanta Debnath, Thierry Galli, Liang Ge, Deborah Goberdhan, Wei Guo, Kangmin He, Ralf Jacob, Tiebang Kang, Min Goo Lee, Lian Li, Fabio Lolicato, Jun Lu, Vivek Malhotra, Walter Nickel, Vassiliki Nikoletopoulou, Stacey K. Ogden, Georgia Maria Sagia, Feng Shao, Anbing Shi, Clotilde Thery, Christel Vérollet, Julien Villeneuve, Frederik Verweij, Yanzhuang Wang, Juan Wang, Shenjie Wu, Yihong Ye, Hang Yin, Li Yu, Min Zhang, Ying Zhang, Xin Zhou, Chiara Zurzolo   +34 more
wiley   +1 more source

The placozoan Trichoplax

Nature Methods
After having been largely neglected for more than a century, the tiny marine animal Trichoplax adhaerens is enjoying a revival and is now poised to become a mainstream model organism for the study of epithelial evolution, diversification and specialization.
Leria, Marvin, Requin, Magali, Le Bivic, André, Pasini, Andrea   +3 more
openaire   +2 more sources

Concatenated analysis sheds light on early metazoan evolution and fuels a modern "urmetazoon" hypothesis. [PDF]

PLoS Biology, 2009
For more than a century, the origin of metazoan animals has been debated. One aspect of this debate has been centered on what the hypothetical "urmetazoon" bauplan might have been.
Bernd Schierwater, Michael Eitel, Wolfgang Jakob, Hans-Jürgen Osigus, Heike Hadrys, Stephen L Dellaporta, Sergios-Orestis Kolokotronis, Rob Desalle   +7 more
doaj   +1 more source

Invertebrate Bile Acid‐Sensitive Ion Channels and Their Emergence in Bilateria

The FASEB Journal, Volume 39, Issue 8, 30 April 2025.
This graphical abstract presents the evolutionary distribution and functional characteristics of bile acid‐sensing ion channels (BASICs) across bilaterians. A phylogenetic tree illustrates the presence of BASICs in diverse groups, extending beyond previously established mammalian findings.
Josep Martí‐Solans, Aina Børve, Line Vevle, Andreas Hejnol, Timothy Lynagh   +4 more
wiley   +1 more source

Domain‐Shuffling in the Evolution of Cyclostomes and Gnathostomes

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 2, Page 59-79, March 2025.
We addressed the potential roles of domain‐shuffling origin genes (DSO‐Gs) in the evolution of early vertebrates. Through comparative genome analysis of 22 metazoans, including four cyclostomes, we identified DSO‐Gs before and after the divergence of cyclostomes and gnathostomes, and suggest domain shuffling as a key mechanism in vertebrate early ...
Hirofumi Kariyayama, Takeshi Kawashima, Hiroshi Wada, Haruka Ozaki   +3 more
wiley   +1 more source

Studying Placozoa WBR in the Simplest Metazoan Animal, Trichoplax adhaerens

, 2022
AbstractPlacozoans are a promising model system to study fundamental regeneration processes in a morphologically and genetically very simple animal. We here provide a brief introduction to the enigmatic Placozoa and summarize the state of the art of animal handling and experimental manipulation possibilities.
Hans-Jürgen Osigus, Michael Eitel, Karolin Horn, Kai Kamm, Jennifer Kosubek-Langer, Moritz Jonathan Schmidt, Heike Hadrys, Bernd Schierwater   +7 more
openaire   +2 more sources

Developmental gene expression in the eyes of the pygmy squid Xipholeptos notoides

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 342, Issue 7, Page 483-498, November 2024.
In the cephalopod Xipholeptos notoides, the photosensitive pigment encoding genes Rhodopsin, Xenopsin, and Retinochrome, as well as two Reflectin genes are expressed in the olfactory organ. This suggests that either opsins may not only be involved in photoreception or the olfactory organ is involved in photoreception.
David Koller, Kevin M. Kocot, Bernard M. Degnan, Tim Wollesen   +3 more
wiley   +1 more source

Evolution of the Cdk4/6–Cdkn2 system in invertebrates

Genes to Cells, Volume 29, Issue 11, Page 1037-1051, November 2024.
Hypothesis on the evolution of the Cdkn2 locus. (a) Loss of Cdkn2 occurred multiple times. (b) Evolution of microsynteny at the Cdkn2 locus. Cdkn2e is a hypothetical transient gene. Abstract The cell cycle is driven by cyclin‐dependent kinases (Cdks). The decision whether the cell cycle proceeds is made during G1 phase, when Cdk4/6 functions.
Shiori Yuki, Shunsuke Sasaki, Yuta Yamamoto, Fumika Murakami, Kazumi Sakata, Isato Araki   +5 more
wiley   +1 more source

The origin and evolution of G protein-coupled receptor kinases. [PDF]

PLoS ONE, 2012
G protein-coupled receptor (GPCR) kinases (GRKs) play key role in homologous desensitization of GPCRs. GRKs phosphorylate activated receptors, promoting high affinity binding of arrestins, which precludes G protein coupling.
Arcady Mushegian, Vsevolod V Gurevich, Eugenia V Gurevich   +2 more
doaj   +1 more source