Comparative genomics and the nature of placozoan species. [PDF]
PLoS Biology, 2018 Placozoans are a phylum of nonbilaterian marine animals currently represented by a single described species, Trichoplax adhaerens, Schulze 1883. Placozoans arguably show the simplest animal morphology, which is identical among isolates collected ...
Michael Eitel +10 more
doaj +1 more source
Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors [PDF]
, 2008 Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to each other are not fully understood.
Michael E. Baker
core +1 more source
Animal HECT ubiquitin ligases: evolution and functional implications [PDF]
, 2010 12 pages, 6 figures, 1 table, 3 additional files.[Background] HECT ubiquitin ligases (HECT E3s) are key components of the eukaryotic ubiquitin-proteasome system and are involved in the genesis of several human diseases.
Ignacio Marín
core +3 more sources
Beyond the Secretory Pathway: New Insights Into Protein Release
Traffic, Volume 26, Issue 10-12, October/December 2025.While proteins bearing N‐terminal signal or leader sequences are secreted via the ER‐Golgi‐plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling sequence can be secreted via poorly defined mechanisms termed Unconventional Protein Secretion (UcPS).
Ruey‐Hwa Chen +34 more
wiley +1 more source
Global diversity of the Placozoa.
PLoS ONE, 2013 The enigmatic animal phylum Placozoa holds a key position in the metazoan Tree of Life. A simple bauplan makes it appear to be the most basal metazoan known and genetic evidence also points to a position close to the last common metazoan ancestor ...
Michael Eitel +3 more
doaj +1 more source
Concatenated analysis sheds light on early metazoan evolution and fuels a modern "urmetazoon" hypothesis. [PDF]
PLoS Biology, 2009 For more than a century, the origin of metazoan animals has been debated. One aspect of this debate has been centered on what the hypothetical "urmetazoon" bauplan might have been.
Bernd Schierwater +7 more
doaj +1 more source
Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans [PDF]
, 2010 Background zic genes are members of the gli/glis/nkl/zic super-family of C2H2 zinc finger (ZF) transcription factors. Homologs of the zic family have been implicated in patterning neural and mesodermal tissues in bilaterians ...
Michael J Layden +4 more
core +2 more sources
Nature MethodsAfter having been largely neglected for more than a century, the tiny marine animal Trichoplax adhaerens is enjoying a revival and is now poised to become a mainstream model organism for the study of epithelial evolution, diversification and specialization.
Leria, Marvin +3 more
openaire +2 more sources
Invertebrate Bile Acid‐Sensitive Ion Channels and Their Emergence in Bilateria
The FASEB Journal, Volume 39, Issue 8, 30 April 2025.This graphical abstract presents the evolutionary distribution and functional characteristics of bile acid‐sensing ion channels (BASICs) across bilaterians. A phylogenetic tree illustrates the presence of BASICs in diverse groups, extending beyond previously established mammalian findings.
Josep Martí‐Solans +4 more
wiley +1 more source
Long-term dynamics of placozoan culture: emerging models for population and space biology
Frontiers in Cell and Developmental BiologyAs the simplest free-living animal, Trichoplax adhaerens (Placozoa) is emerging as a powerful paradigm to decipher molecular and cellular bases of behavior, enabling integrative studies at all levels of biological organization in the context of metazoan ...
Daria Y. Romanova +6 more
doaj +1 more source