Phylogenetic analysis of the endoribonuclease Dicer family. [PDF]
PLoS ONE, 2014 Dicers are proteins of the ribonuclease III family with the ability to process dsRNA, involved in regulation of gene expression at the post-transcriptional level.
Zeqian Gao +4 more
doaj +1 more source
Molecular mechanisms of perilipin protein function in lipid droplet metabolism
FEBS Letters, Volume 598, Issue 10, Page 1170-1198, May 2024.Lipid droplets (LDs) are important for the storage of energy and lipid components. The perilipin family in mammals includes five proteins (PLIN1 to PLIN5), all of which are abundant on the surface of LDs in different tissues and play a role in LD stability and degradation by lipases.
Elena Griseti +7 more
wiley +1 more source
Evolution of the perlecan/HSPG2 gene and its activation in regenerating Nematostella vectensis. [PDF]
PLoS ONE, 2015 The heparan sulfate proteoglycan 2 (HSPG2)/perlecan gene is ancient and conserved in all triploblastic species. Its presence maintains critical cell boundaries in tissue and its large (up to ~900 kDa) modular structure has prompted speculation about the ...
Curtis R Warren +5 more
doaj +1 more source
Beauty in the beast – Placozoan biodiversity explored through molluscan predator genomics
Ecology and Evolution, Volume 14, Issue 4, April 2024.Previous assumptions about the primary habitat of Placozoa are challenged, and their broader diversity beyond disc‐shaped grazers in coastal waters is revealed. The discovery of placozoan‐predatory sea slugs prompts consideration of a new ecological niche: seafloor sediment interstices.
Michael Eitel +3 more
wiley +1 more source
Independent elaboration of steroid hormone signaling pathways in Metazoans [PDF]
, 2009 Steroid hormones regulate many physiological processes in vertebrates, nematodes and arthropods through binding to nuclear receptors (NR), a metazoan-specific family of ligand-activated transcription factors.
Gabriel V. Markov +5 more
core +3 more sources
Proteoglycans in mechanobiology of tissues and organs: Normal functions and mechanopathology
Proteoglycan Research, Volume 2, Issue 2, April-June 2024.Abstract Proteoglycans (PGs) are a diverse class of glycoconjugates that serve critical functions in normal mechanobiology and mechanopathology. Both the protein cores and attached glycosaminoglycan (GAG) chains function in mechanically sensitive processes, and loss of either can contribute to development of pathological conditions. PGs function as key
Mary C. Farach‐Carson +2 more
wiley +1 more source
Trichoplax neuropeptide controls movement without nerves [PDF]
Journal of Experimental Biology, 2017 ![Figure][1] Two paused Trichoplax adhaerens feeding on a bed of microalgae (dark particles). Photo credit: Carolyn Smith. Gliding on microscopic beating hairs as it grazes upon microalgae coating surfaces in warm oceans, tiny Trichoplax adhaerens is one of the most ancient and ...
openaire +1 more source
Alternative NAD(P)H dehydrogenase and alternative oxidase: proposed physiological roles in animals [PDF]
, 2019 The electron transport systems in mitochondria of many organisms contain alternative respiratory enzymes distinct from those of the canonical respiratory system depicted in textbooks.
Gospodaryov, Dmytro V. +1 more
core +1 more source
The evolution and comparative neurobiology of endocannabinoid signalling [PDF]
, 2012 CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A. +4 more
core +1 more source
Importance of fatty acid binding proteins in cellular function and organismal metabolism
Journal of Cellular and Molecular Medicine, Volume 28, Issue 5, March 2024.Abstract Fatty acid binding proteins (Fabps) are small soluble proteins that are abundant in the cytosol. These proteins are known to bind a myriad of small hydrophobic molecules and have been postulated to serve a variety of roles, yet their precise functions have remained an enigma over half a century of study.
Luis B. Agellon
wiley +1 more source