Results 21 to 30 of about 39,692 (259)

Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation

open access: yesCell Communication and Signaling, 2023
Background Idiosyncratic drug-induced liver injury (IDILI) is common in hepatology practices and, in some cases, lethal. Increasing evidence show that tricyclic antidepressants (TCAs) can induce IDILI in clinical applications but the underlying ...
Wenqing Mu   +12 more
doaj   +1 more source

Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice [PDF]

open access: yes, 2015
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Antonio, Caretta   +6 more
core   +8 more sources

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]

open access: yes, 2020
Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core   +1 more source

Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]

open access: yes, 2006
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Andrews, Elizabeth   +5 more
core   +2 more sources

Association between mortality from suicide in England and antidepressant prescribing: an ecological study

open access: yesBMC Public Health, 2004
Background Antidepressant prescribing has been increasing in England. Studies in other countries suggest that while this may be associated with reduced suicide rates, it may also be associated with increased fatal poisoning from antidepressant drugs.
Majeed Azeem   +2 more
doaj   +1 more source

Antidepressants with antimicrobial activity? A promising therapeutic strategy

open access: yesMedicina Universitaria, 2022
Antidepressants are currently positioned as one of the main drugs prescribed and consumed worldwide, commonly used for the pharmacological management of certain psychiatric disorders, mainly depression.
Gloria M. González   +4 more
doaj   +1 more source

The progress and development of antidepressants [PDF]

open access: yesE3S Web of Conferences, 2021
Major depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders.
Li Keyang, Diao Shiqi
doaj   +1 more source

Antidepressants in pregnancy and breastfeeding [PDF]

open access: yes, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Sved-Williams, A.
core   +1 more source

The Antidepressant Effect of Pizotifen in Depressed Patients with Tension H ead ach e - A Controlled Study with Trazodone and Placebo

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Pizotifen, a tricyclic compound is a derivative of benzocycloheptathiophene and it is used in the prophylaxis of migraine. In som e studies, it has been claimed that pizotifen hasalso an antidepressant effect and displays rather atetracyclic ...
Kemal GÖKSAN   +3 more
doaj  

Toxic Ingestion/Acute Tricyclic Antidepressant (TCA) Ingestion

open access: yesMedEdPORTAL, 2015
Introduction Acute tricyclic antidepressant (TCA) overdose is an uncommon but life threatening ingestion. The purpose of this simulation is to present an acute TCA overdose case that allows medical students, emergency medicine residents, and pediatric ...
Bryan Beaver, Mary Wittler
doaj   +1 more source

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