Results 31 to 40 of about 172,947 (390)

Antidepressants with antimicrobial activity? A promising therapeutic strategy

Medicina Universitaria, 2022
Antidepressants are currently positioned as one of the main drugs prescribed and consumed worldwide, commonly used for the pharmacological management of certain psychiatric disorders, mainly depression.
Gloria M. González, Alexandra M. Montoya, Angel Andrade-Torres, Miguel A. Becerril-García, Rogelio de J. Treviño-Rangel   +4 more
doaj   +1 more source

The progress and development of antidepressants [PDF]

E3S Web of Conferences, 2021
Major depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders.
Li Keyang, Diao Shiqi
doaj   +1 more source

Incidence and drug treatment of emotional distress after cancer diagnosis : a matched primary care case-control study [PDF]

, 2012
Notes This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License.Peer ...
A J Lee, C Bond, C Burton, C Burton, DR Cox, E Martin-Merino, F Desplenter, F Hansen, G Laekeman, G Rait, J Madden, JC Holland, JL Roffman, K Lefevre, KC Yung, L Hodges, M Miovic, M Sharpe, M Vahdaninia, M Watson, MB First, MJ Massie, NF Khan, P Lockhart, P Murchie, PP Roy-Byrne, R Morris, R Munoz-Arroyo, RA Lewis, S Simoens, S Wein, SB Patten, TL Deshields, V Strong   +33 more
core   +1 more source

Tricyclic Antidepressant Amitriptyline Activates Fibroblast Growth Factor Receptor Signaling in Glial Cells

Journal of Biological Chemistry, 2011
Recently, both clinical and animal studies demonstrated neuronal and glial plasticity to be important for the therapeutic action of antidepressants. Antidepressants increase glial cell line-derived neurotrophic factor (GDNF) production through monoamine ...
K. Hisaoka, Mami Tsuchioka, Ryoya Yano, Natsuko Maeda, N. Kajitani, N. Morioka, Y. Nakata, M. Takebayashi   +7 more
semanticscholar   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
core   +1 more source

Association between mortality from suicide in England and antidepressant prescribing: an ecological study

BMC Public Health, 2004
Background Antidepressant prescribing has been increasing in England. Studies in other countries suggest that while this may be associated with reduced suicide rates, it may also be associated with increased fatal poisoning from antidepressant drugs.
Majeed Azeem, Griffiths Clare, Morgan Oliver WC   +2 more
doaj   +1 more source

Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]

, 2006
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Andrews, Elizabeth, Mines, Daniel, Roskell, Neil, Rubino, Annalisa, Tennis, Pat, Weich, Scott   +5 more
core   +2 more sources

Development and Validation of eRADAR: A Tool Using EHR Data to Detect Unrecognized Dementia. [PDF]

, 2020
ObjectivesEarly recognition of dementia would allow patients and their families to receive care earlier in the disease process, potentially improving care management and patient outcomes, yet nearly half of patients with dementia are undiagnosed. Our aim
Barnes, Deborah E, Boscardin, W John, Dublin, Sascha, Larson, Eric B, Lee, Sei J, Marcum, Zachary A, Walker, Rod L, Zhou, Jing   +7 more
core   +2 more sources

Toxic Ingestion/Acute Tricyclic Antidepressant (TCA) Ingestion

MedEdPORTAL, 2015
Introduction Acute tricyclic antidepressant (TCA) overdose is an uncommon but life threatening ingestion. The purpose of this simulation is to present an acute TCA overdose case that allows medical students, emergency medicine residents, and pediatric ...
Bryan Beaver, Mary Wittler
doaj   +1 more source

Potential antidepressant effects of a dietary supplement from the chlorella and lion's mane mushroom complex in aged SAMP8 mice

Frontiers in Nutrition, 2022
Since the 1990s, the prevalence of mental illnesses, such as depression, has been increasing annually and has become a major burden on society. Due to the many side effects of antidepressant drugs, the development of a complementary therapy from natural ...
Ming-Yu Chou, Jou-Hsuan Ho, Mao-Jung Huang, Ying-Ju Chen, Mei-Due Yang, Liang-Hung Lin, Ching-Hsin Chi, Chin-Hsi Yeh, Tsui-Ying Tsao, Jian-Kai Tzeng, Rachel Jui-cheng Hsu, Ping-Hsiu Huang, Wen-Chien Lu, Po-Hsien Li, Ming-Fu Wang, Ming-Fu Wang   +15 more
doaj   +1 more source