Results 31 to 40 of about 157,293 (343)
ObjectivesA marked decline in suicide rates has co-occurred with increased antidepressant sales in several countries but the causal connection between the trends remains debated.
Heta Moustgaard+3 more
doaj +1 more source
We report a case of profound neurologic and cardiovascular manifestations of tricyclic antidepressant intoxication following self-poisoning with multiple pharmaceuticals including amitriptyline in excess of 43 mg/kg, in a 51-year-old male. Institution of
M. Harvey, G. Cave
semanticscholar +1 more source
Abstract Background Despite some evidence that psoriatic arthritis (PsA) may increase psychological burden in psoriasis, the mental health of this subpopulation is under‐investigated. Objectives To investigate whether PsA is associated with higher depression and anxiety in moderate‐to‐severe psoriasis; explore whether pain mediates these associations ...
Georgia Lada+5 more
wiley +1 more source
Antidepressants with antimicrobial activity? A promising therapeutic strategy
Antidepressants are currently positioned as one of the main drugs prescribed and consumed worldwide, commonly used for the pharmacological management of certain psychiatric disorders, mainly depression.
Gloria M. González+4 more
doaj +1 more source
The progress and development of antidepressants [PDF]
Major depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders.
Li Keyang, Diao Shiqi
doaj +1 more source
Abstract Medically unexplained dermatologic symptoms, such as pruritus, numbness and burning are known as somatization. These cutaneous symptoms can be very difficult to treat because of an absence of an objective explanation and they may not fit neatly into any known dermatological or psychiatric condition.
George W. M. Millington+3 more
wiley +1 more source
Recently, both clinical and animal studies demonstrated neuronal and glial plasticity to be important for the therapeutic action of antidepressants. Antidepressants increase glial cell line-derived neurotrophic factor (GDNF) production through monoamine ...
K. Hisaoka+7 more
semanticscholar +1 more source
Background Antidepressant prescribing has been increasing in England. Studies in other countries suggest that while this may be associated with reduced suicide rates, it may also be associated with increased fatal poisoning from antidepressant drugs.
Majeed Azeem+2 more
doaj +1 more source
Toxic Ingestion/Acute Tricyclic Antidepressant (TCA) Ingestion
Introduction Acute tricyclic antidepressant (TCA) overdose is an uncommon but life threatening ingestion. The purpose of this simulation is to present an acute TCA overdose case that allows medical students, emergency medicine residents, and pediatric ...
Bryan Beaver, Mary Wittler
doaj +1 more source
A dose-effect network meta-analysis model: an application in antidepressants [PDF]
Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA applications typically ignore the role that drugs dosage play on the results.
arxiv +1 more source