Results 31 to 40 of about 157,293 (343)

Antidepressant sales and the risk for alcohol-related and non-alcohol-related suicide in Finland--an individual-level population study.

open access: yesPLoS ONE, 2014
ObjectivesA marked decline in suicide rates has co-occurred with increased antidepressant sales in several countries but the causal connection between the trends remains debated.
Heta Moustgaard   +3 more
doaj   +1 more source

Case report: successful lipid resuscitation in multi-drug overdose with predominant tricyclic antidepressant toxidrome

open access: yesInternational Journal of Emergency Medicine, 2012
We report a case of profound neurologic and cardiovascular manifestations of tricyclic antidepressant intoxication following self-poisoning with multiple pharmaceuticals including amitriptyline in excess of 43 mg/kg, in a 51-year-old male. Institution of
M. Harvey, G. Cave
semanticscholar   +1 more source

Associations between psoriatic arthritis and mental health among patients with psoriasis: A replication and extension study using the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR)

open access: yesSkin Health and Disease, Volume 2, Issue 4, December 2022., 2022
Abstract Background Despite some evidence that psoriatic arthritis (PsA) may increase psychological burden in psoriasis, the mental health of this subpopulation is under‐investigated. Objectives To investigate whether PsA is associated with higher depression and anxiety in moderate‐to‐severe psoriasis; explore whether pain mediates these associations ...
Georgia Lada   +5 more
wiley   +1 more source

Antidepressants with antimicrobial activity? A promising therapeutic strategy

open access: yesMedicina Universitaria, 2022
Antidepressants are currently positioned as one of the main drugs prescribed and consumed worldwide, commonly used for the pharmacological management of certain psychiatric disorders, mainly depression.
Gloria M. González   +4 more
doaj   +1 more source

The progress and development of antidepressants [PDF]

open access: yesE3S Web of Conferences, 2021
Major depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders.
Li Keyang, Diao Shiqi
doaj   +1 more source

Somatization in dermatology

open access: yesSkin Health and Disease, Volume 2, Issue 4, December 2022., 2022
Abstract Medically unexplained dermatologic symptoms, such as pruritus, numbness and burning are known as somatization. These cutaneous symptoms can be very difficult to treat because of an absence of an objective explanation and they may not fit neatly into any known dermatological or psychiatric condition.
George W. M. Millington   +3 more
wiley   +1 more source

Tricyclic Antidepressant Amitriptyline Activates Fibroblast Growth Factor Receptor Signaling in Glial Cells

open access: yesJournal of Biological Chemistry, 2011
Recently, both clinical and animal studies demonstrated neuronal and glial plasticity to be important for the therapeutic action of antidepressants. Antidepressants increase glial cell line-derived neurotrophic factor (GDNF) production through monoamine ...
K. Hisaoka   +7 more
semanticscholar   +1 more source

Association between mortality from suicide in England and antidepressant prescribing: an ecological study

open access: yesBMC Public Health, 2004
Background Antidepressant prescribing has been increasing in England. Studies in other countries suggest that while this may be associated with reduced suicide rates, it may also be associated with increased fatal poisoning from antidepressant drugs.
Majeed Azeem   +2 more
doaj   +1 more source

Toxic Ingestion/Acute Tricyclic Antidepressant (TCA) Ingestion

open access: yesMedEdPORTAL, 2015
Introduction Acute tricyclic antidepressant (TCA) overdose is an uncommon but life threatening ingestion. The purpose of this simulation is to present an acute TCA overdose case that allows medical students, emergency medicine residents, and pediatric ...
Bryan Beaver, Mary Wittler
doaj   +1 more source

A dose-effect network meta-analysis model: an application in antidepressants [PDF]

open access: yes, 2021
Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA applications typically ignore the role that drugs dosage play on the results.
arxiv   +1 more source

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