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Efficacy and Safety of Two Salts of Trientine in the Treatment of Wilson’s Disease
Journal of Clinical Medicine, 2022 Background: Wilson’s disease (WD) is one of the few genetic disorders that can be successfully treated with pharmacological agents. Copper-chelating agents (D-penicillamine and Trientine salts) and zinc salts have been demonstrated to be effective. There
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European Journal of Drug Metabolism and Pharmacokinetics, 2021
Wilson disease (WD) is an autosomal recessive inherited disorder of copper metabolism. Chelation of excessive copper is recommended but data on the pharmacokinetics of trientine are limited. The aim of this study was to compare the pharmacokinetics of a new trientine tetrahydrochloride formulation (TETA 4HCl) with those of an established trientine ...
Karl Heinz Weiss +7 more
openaire +2 more sources
Wilson disease (WD) is an autosomal recessive inherited disorder of copper metabolism. Chelation of excessive copper is recommended but data on the pharmacokinetics of trientine are limited. The aim of this study was to compare the pharmacokinetics of a new trientine tetrahydrochloride formulation (TETA 4HCl) with those of an established trientine ...
Karl Heinz Weiss +7 more
openaire +2 more sources