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Efficacy and Safety of Two Salts of Trientine in the Treatment of Wilson’s Disease
Journal of Clinical Medicine, 2022 Background: Wilson’s disease (WD) is one of the few genetic disorders that can be successfully treated with pharmacological agents. Copper-chelating agents (D-penicillamine and Trientine salts) and zinc salts have been demonstrated to be effective. There
Dominique Debray +2 more
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Novel melatonin-trientine conjugate as potential therapeutic agents for Alzheimer's disease.
Bioorganic chemistry (Print), 2022Researchers continue to explore drug targets to treat the characteristic pathologies of Alzheimer's disease (AD). Some drugs relieve the pathological processes of AD to some extent, but the failed clinical trials indicate that multifunctional agents seem
Lin-bo Li +10 more
semanticscholar +1 more source
Voprosy praktičeskoj pediatrii
The pathogenetic method of treating Wilson's disease (WD) is the prescription of copper chelators. The first-line therapy drug is D-penicillamine; if it is ineffective or causes adverse effects, trientine is prescribed.
M. Bagaeva +4 more
semanticscholar +1 more source
The pathogenetic method of treating Wilson's disease (WD) is the prescription of copper chelators. The first-line therapy drug is D-penicillamine; if it is ineffective or causes adverse effects, trientine is prescribed.
M. Bagaeva +4 more
semanticscholar +1 more source
Drug Research
Cognitive impairments affect millions of people worldwide with an increasing prevalence. Research on their etiology and treatment is developing, nevertheless significant gaps remain.
Kian Mousavi-Nasab +2 more
semanticscholar +1 more source
Cognitive impairments affect millions of people worldwide with an increasing prevalence. Research on their etiology and treatment is developing, nevertheless significant gaps remain.
Kian Mousavi-Nasab +2 more
semanticscholar +1 more source
Treatment of nickel dermatitis with Trientine
Contact Dermatitis, 198623 nickel‐sensitive patients with hand eczema were treated with Trientine 300 mg daily and a placebo in a double‐blind, crossover trial. No significant improvement occurred in the hand eczema. A surprising finding was that there was no detectable increase in urinary nickel excretion, in contrast animal studies.
D, Burrows +6 more
openaire +2 more sources