Results 51 to 60 of about 3,603 (218)

Acetic Acid-Promoted Photoredox Catalyzed Trifluoromethylation of Aldehyde Hydrazones

, 2022
Radical C(sp2)-H trifluoromethylation of aromatic aldehyde hydrazones is achieved in moderate to high yields under oxidative photoredox catalysis conditions, using inexpensive, bench-stable sodium trifluoromethanesulfinate (Langlois reagent), and Rose ...
Reddy, V. Prakash, Rafiu, Raheemat, Aryal, Puspa   +2 more
core   +1 more source

Asymmetric Preparation of α-Quaternary Fluorinated β-keto Esters. Review

Molecules, 2020
In this review, recent advances over the past decade in the preparation of fluorinated stereogenic quaternary centers on β-keto esters compounds are analyzed.
Albert Granados, Adelina Vallribera
doaj   +1 more source

Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations

Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera, Francesco Basoccu, Andrea Porcheddu   +2 more
wiley   +2 more sources

Metal- and Oxidant-Free Photoinduced Aromatic Trifluoromethylation Performed in Aerated Gel Media: Determining the Effects on Yield and Selectivity

Molecules, 2018
In this work we have investigated the potential benefits of using supramolecular gel networks as reaction media to carry out air-sensitive metal-free light-induced trifluoromethylation of six-membered (hetero)arenes under aerobic conditions.
Alex Abramov, Hendrik Vernickel, César Saldías, David Díaz Díaz   +3 more
doaj   +1 more source

The C3-H Bond Functionalization of Quinoxalin-2(1H)-Ones With Hypervalent Iodine(III) Reagents

Frontiers in Chemistry, 2020
The modification of quinoxalin-2(1H)-ones via direct C-H bond functionalization has begun to receive widespread attention, due to quinoxalin-2(1H)-one derivatives' various biological activities and pharmaceutical properties. This mini review concentrates
Yushi Tan, Jiabo Wang, Hong-Yu Zhang, Yuecheng Zhang, Jiquan Zhao   +4 more
doaj   +1 more source

Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices

Angewandte Chemie Novit, Volume 2, Issue 3, September 2026.
Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that can help address them. While focusing on the practical application of ML tools in real‐world laboratory settings, we outline prerequisites, emerging ...
Niklas Hölter, Felix Katzenburg, Florian Boser, Frank Glorius   +3 more
wiley   +1 more source

Photo-driven redox-neutral decarboxylative carbon-hydrogen trifluoromethylation of (hetero)arenes with trifluoroacetic acid

Nature Communications, 2017
C–H bond functionalization has become an important tool for many organic transformations, however such reactions typically require stoichiometric amounts of external oxidants.
Jin Lin, Zhi Li, Jian Kan, Shijun Huang, Weiping Su, Yadong Li   +5 more
doaj   +1 more source

Activation of SF₅CF₃ by the N-Heterocyclic Carbene SIMes

Molecules, 2023
The greenhouse gas SF5CF3 was photochemically activated with SIMes (1,3-Bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene) to give 1,3-dimesityl-2,2-difluoroimidazolidine (SIMesF2), and 1,3-dimesitylimidazolidine-2-sulfide, as well as the ...
Domenique Herbstritt, Pooja Tomar, Thomas Braun   +2 more
doaj   +1 more source

Overview of Photochemical Reactions for the Synthesis of Aza and Oxa‐Spirocyclic Compounds Under Visible Light Irradiation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review presents the visible‐light‐mediated photochemical reaction for the synthesis of aza, oxa, and aza–oxa spirocyclic compounds via photoinduced electron transfer (PET), hydrogen atom transfer (HAT), single‐electron transfer (SET), or energy transfer (EnT) pathways.
Annu Bhardwaj, Shivangi Jaiswal, Khushboo Bhardwaj, Swapnil Sharma, Jaya Dwivedi   +4 more
wiley   +1 more source

Nucleophilic trifluoromethylation of electron-deficient arenes [PDF]

, 2017
A new trifluoromethylation of arenes is presented, which proceeds via a Ru(ii) π–arene complex and is carried out under mild reaction conditions.
Jack A. Pike, James W. Walton, Pike, Jack A., Walton, James William   +3 more
core   +1 more source