Results 61 to 70 of about 1,340 (176)

Photocatalytic fluoroalkylation by ligand-to-metal charge transfer

Frontiers in Chemistry
Trifluoromethyl (CF3) and other fluoroalkyl groups are of great significance in the fields of pharmaceutical chemistry and agricultural chemicals. Fluoroalkyl acids, especially trifluoroacetic acid (TFA) is considered the most ideal fluoroalkylation ...
Jingyi Liu, Zhenwei Cui, Jingjing Bi, Xing He, Qingjie Ding, Hong Zhu, Chunhua Ma   +6 more
doaj   +1 more source

THE RADICAL C-H FUNCTIONALIZATION OF NATURAL COMPOUNDS

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2019
Selective functionalization of complex scaffolds is a promising approach to increase the pharmacological profiles of natural products and their derivatives.
Vladilena GÎRBU
doaj  

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

Beilstein Journal of Organic Chemistry, 2010
Since the discovery by Yagupolskii and co-workers that S-trifluoromethyl diarylsulfonium salts are effective for the trifluoromethylation of thiophenolates, the design and synthesis of electrophilic trifluoromethylating reagents have been extensively ...
Norio Shibata, Andrej Matsnev, Dominique Cahard   +2 more
doaj   +1 more source

1,6-Nucleophilic Di- and Trifluoromethylation of para-Quinone Methides with Me₃SiCF₂H/Me₃SiCF₃ Facilitated by CsF/18-Crown-6

Molecules
The direct 1,6-nucleophilic difluoromethylation, trifluoromethylation, and difluoroalkylation of para-quinone methides (p-QMs) with Me3SiRf (Rf = CF2H, CF3, CF2CF3, CF2COOEt, and CF2SPh) under mild conditions are described. Although Me3SiCF2H shows lower
Dingben Chen, Ling Huang, Mingyu Liang, Xiaojing Chen, Dongdong Cao, Pan Xiao, Chuanfa Ni, Jinbo Hu   +7 more
doaj   +1 more source

Carbon–carbon bond cleavage for Cu-mediated aromatic trifluoromethylations and pentafluoroethylations

Beilstein Journal of Organic Chemistry, 2015
This short review highlights the copper-mediated fluoroalkylation using perfluoroalkylated carboxylic acid derivatives. Carbon–carbon bond cleavage of perfluoroalkylated carboxylic acid derivatives takes place in fluoroalkylation reactions at high ...
Tsuyuka Sugiishi, Hideki Amii, Kohsuke Aikawa, Koichi Mikami   +3 more
doaj   +1 more source

CF3SO2X (X = Na, Cl) as reagents for trifluoromethylation, trifluoromethylsulfenyl-, -sulfinyl- and -sulfonylation and chlorination. Part 2: Use of CF3SO2Cl

Beilstein Journal of Organic Chemistry, 2017
The recent progresses of the application of trifluoromethanesulfonyl chloride, CF3SO2Cl, in the formation of C–CF3, C–SCF3, C–SOCF3, and C–Cl bonds are summarised in this second part of a two-part review published back-to-back on both sodium ...
Hélène Chachignon, Hélène Guyon, Dominique Cahard   +2 more
doaj   +1 more source

1,2-Oxidative Trifluoromethylation of Olefin with Ag(O₂CCF₂SO₂F) and O₂: Synthesis of α-Trifluoromethyl Ketones

Molecules
A novel and efficient 1,2-oxidative trifluoromethylation of olefins employing Ag(O2CCF2SO2F) as a trifluoromethyl source is described with O2 as the oxidant, which provides access to a variety of valuable α-trifluoromethyl-substituted ketones.
Shengxue Zhang, Wangchuan Xiao, Jingjing Wu, Fanhong Wu, Houjin Huang, Xiaoyu Ma, Yafei Shi, Chao Liu   +7 more
doaj   +1 more source

Visible-light-induced radical cascade cyclization: a catalyst-free synthetic approach to trifluoromethylated heterocycles

Beilstein Journal of Organic Chemistry
A visible-light-promoted research protocol for constructing dihydropyrido[1,2-a]indolone skeletons is herein described proceeding through a cascade cyclization mediated by trifluoromethyl radicals.
Chuan Yang, Wei Shi, Jian Tian, Lin Guo, Yating Zhao, Wujiong Xia   +5 more
doaj   +1 more source

Langlois Reagent: An Efficient Trifluoromethylation Reagent

SynOpen, 2023
K. Anusha, Megha Mahesh, Shikha Shikha, T. M. Rangarajan, Sharda Pasricha   +4 more
doaj   +1 more source

Trifluoromethylation of pyridines through skeletal rearrangement. [PDF]

Chem Sci
Wang H, Bhaduri N, Greaney MF.
europepmc   +1 more source