Results 21 to 30 of about 737 (161)
Photoredox-Mediated, Nickel-Catalyzed Trifluoromethylthiolation of Aryl and Heteroaryl Iodides
, 2022 While trifluoromethylthiolation of aryl halides has been extensively explored, the current methods require complex and/or air-sensitive catalysts. Reported here is a method employing a bench-stable Ni(II) salt and an iridium photocatalyst that can ...
Eric R. King (9136767) +3 more
core +2 more sources
Late-stage trifluoromethylthiolation of benzylic C-H bonds
Nature Communications, 2019 Fluoroalkylation of C-H bonds is a class of reaction highly sought after in medicinal chemistry. Here, the authors report a regioselective organophotoredox-catalyzed, trifluoromethylthiolation of benzylic C-H bonds for a wide variety of alkyl (hetero ...
Wentao Xu +4 more
doaj +1 more source
Recent Synthetic Advances in C-H/N-H Functionalization of 1H-Pyrazoles: Diverse Strategies Across Variously Substituted Scaffolds. [PDF]
Chem RecSystematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Dzedulionytė Müldür K +3 more
europepmc +2 more sources
Beilstein Journal of Organic Chemistry, 2018 Cyclic benziodoxole systems have become a premier scaffold for the design of electrophilic transfer reagents. A particularly intriguing aspect is the fundamental II–IIII tautomerism about the hypervalent bond, which has led in certain cases to a ...
Nico Santschi +3 more
doaj +1 more source
Remote Trifluoromethylthiolation Enabled by Organophotocatalytic C–C Bond Cleavage
, 2020 The first metal-free ring opening/trifluoromethylthiolation of cycloalkanols for the formation of remote C(sp3)–SCF3 bonds has been developed. A variety of trifluoromethylthiolated carbonyl compounds that are otherwise difficult to achieve were ...
Xiang-Yu Chen (2226904) +7 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2013 In the last few years, transition metal-mediated reactions have joined the toolbox of chemists working in the field of fluorination for Life-Science oriented research.
Grégory Landelle +4 more
doaj +1 more source
Photocatalytic Trifluoromethylthiolation of NAcyl Amines
, 2023 A photocatalytic approach for the C(sp3)–H trifluoromethylthiolation of amides under mild reaction conditions is reported. We have developed a protocol that tolerates a large range of functional groups and allows the functionalization of aromatic and ...
Tatiana Besset +5 more
core +1 more source
The Chemical Record, EarlyView.Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider +6 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 20, 27 May 2026.Bridging the gap. Beyond deck functionalization, the ethylene bridges of [2.2]paracyclophanes offer a largely unexploited reactivity landscape. This review showcases strategies to functionalize these bridges and leverage them to build novel cyclophane architectures.
Rongyu Sun +3 more
wiley +1 more source
Ru(II)-catalyzed C7 trifluoromethylthiolation and thioaryla-tion of indolines using bench-stable reagents [PDF]
A Ru(II)-catalyzed C(sp2)-H trifluoromethylthiolation and thioarylation of indolines using bench-stable reagents have been explored. Diversely substituted indolines were successfully functionalized at C7 position in good to excellent yields.
Sumit, - +2 more
core +1 more source