Results 81 to 90 of about 680,951 (211)
British Journal of Pharmacology, EarlyView.Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro +14 more
wiley +1 more source
Chemotherapy-Induced Peripheral Neuropathy Impairs Tertiary Dentine Formation: An In Vivo Study
International Dental JournalIntroduction and aims: Chemotherapy-induced peripheral neuropathy (CIPN) is a common and well-documented adverse effect of chemotherapy, primarily targeting sensory nerves. Sensory nerves play a crucial role in the repair of dentine-pulp complex injuries.
Jun He +5 more
doaj +1 more source
Neural Regeneration Research, 2015 The morphological changes that occur in the taste buds after denervation are not well understood in rats, especially in the contralateral tongue epithelium.
Yi-ke Li +4 more
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, 2015 In general, trigeminal nerve injury is known as a potential risk of many surgical procedures in the oral cavity. Recent literature demonstrated that the risk of nerve injury is correlated with the experience of the surgeon. Therefore, the purpose of this
Deppe, Herbert;Mücke, Thomas;Wagenpfeil, Stefan;Kesting, Marco;Linsenmeyer, Eva;Tölle, Thomas
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Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Neuralgia do trigêmio: estudo de mecanismos e avaliação da participação das endotelinas em um modelo experimental [PDF]
, 2006 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Este estudo avaliou as respostas nociceptivas evocadas por estímulos de diferentes modalidades em ratos submetidos à ...
Chichorro, Juliana Geremias
core
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley +1 more source
D1 and D2 neurons in medial nucleus accumbens participate in chronic orofacial pain phenotypes
PAIN Reports. Introduction:. Trigeminal nerve injuries can lead to different outcomes, such as chronic neuropathic pain. Nevertheless, it is still elusive why different phenotypes of chronic pain development are shown among individuals. Nucleus accumbens (NAc) might
Claudia Daniela Montes-Ángeles, MSc +5 more
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British Journal of Pharmacology, EarlyView.Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman +4 more
wiley +1 more source
Frontiers in PhysiologyMesenchymal stem cells endow various functions, including proliferation, multipotency, migration, etc. Craniofacial bones originate from the cranial neural crest and are developed mainly through intramembranous ossification, which are different from long
Huai-Jin Pi +3 more
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